Collagen, Type VII, alpha 1 (COL7A1) ELISA Kits

COL7A1 encodes the alpha chain of type VII collagen. Additionally we are shipping COL7A1 Antibodies (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
COL7A1 1294 Q02388
COL7A1 12836 Q63870
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Top COL7A1 ELISA Kits at antibodies-online.com

Showing 2 out of 8 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

More ELISA Kits for COL7A1 Interaction Partners

Cow (Bovine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. Study provides evidence that a nonsense mutation in the COL7A1 gene causes recessive epidermolysis bullosa in Vorderwald and Rotes Hohenvieh cattle.

  2. The identified mutation causes a premature stop codon which leads to a truncated protein representing a complete loss of COL7A1 function (p.R1586*). We thus have identified a candidate causative

Human Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. High chimeric COL7A1-UCN2 (show UTS2 ELISA Kits) recurrence is associated with cancer stem cell transition, promoted epithelial-mesenchymal transition in laryngeal cancer.

  2. three unrelated patients with two identical pathogenic compound heterozygous mutations in the COL7A1 gene developed different clinical forms of dystrophic epidermolysis bullosa-epidermolysis bullosa pruriginosa and mild recessive non-Hallopeau-Siemens.

  3. Type VII (show TH ELISA Kits) collagen is distributed particularly at the strained parts of the accommodation system. Type VII (show TH ELISA Kits) collagen was associated with various basement membranes and with ciliary zonules.

  4. specifically binds and sequesters the innate immune activator cochlin (show COCH ELISA Kits) in the lumen of lymphoid conduits

  5. COL7A1 editing via CRISPR/Cas9 in recessive dystrophic epidermolysis bullosa patients' keratinocytes in vitro has been reported.

  6. Patients with RDEB carry mutations in the COL7A1 gene encoding for type VII (show TH ELISA Kits) collagen, the main component of anchoring fibrils, microstructures responsible for the anchorage of the epidermis to the underlying dermis. [review]

  7. we have identified a novel glycine substitution mutation of the COL7A1 gene in two unrelated Scottish families with a DDEB phenotype. This mutation abolishes the donor splice site and results in in-frame exon skipping. This leads to dominant negative interference between the wild-type and truncated-type collagen proteins resulting in a mild phenotype.

  8. Case Report: glycine substitution specific to COL7A1, exon 110, was identified in a Chinese family with epidermolysis bullosa pruriginosa.

  9. COL7A1 harbored mutations in the overwhelming majority of patients with dystrophic epidermolysis bullosa, and most of them in this Iranian cohort were consistent with autosomal recessive inheritance. Ninety percent of these mutations were homozygous recessive, reflecting consanguinity in these families.

  10. miR (show MLXIP ELISA Kits)-29 Regulates COL7A1 in Recessive Dystrophic Epidermolysis Bullosa, directly through targeting its 3' untranslated region at two distinct seed regions and indirectly through targeting an essential transcription factor required for basal COL7A1 expression, SP1 (show PSG1 ELISA Kits).

Mouse (Murine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. specifically binds and sequesters the innate immune activator cochlin (show COCH ELISA Kits) in the lumen of lymphoid conduits

  2. miR (show MLXIP ELISA Kits)-29 Regulates COL7A1 in Recessive Dystrophic Epidermolysis Bullosa, directly through targeting its 3' untranslated region at two distinct seed regions and indirectly through targeting an essential transcription factor required for basal COL7A1 expression, SP1 (show SP1 ELISA Kits)

  3. The cystine knot is N-terminal to the collagen triple helix in in collagen type VII (show TH ELISA Kits) and IX and therefore probably impedes unfolding of the collagen triple helix from the N terminus.

  4. COL7A1 is required for re-epithelialization through organization of laminin-332 at the dermal-epidermal junction during wound healing.

  5. Tissue-bound, but not circulating, complement-fixing COL7-specific autoantibodies are associated with T helper type (Th)1 (show TH1L ELISA Kits) cell type cytokine expression and response in mice seusceptible to epidermolysis bullosa acquisita.

  6. An interaction of mvWFA2 with its neighboring domain mFNIII-9 was characterized with NMR spectroscopy and SPR

  7. transforming growth factor beta1 stimulation of Col7a1 transcription is dependent on a putative interaction between Smads and AP1 (show JUN ELISA Kits).

  8. single amino acid substitutions in procollagen VII (show TH ELISA Kits) alter its self-assembly

  9. All mice developed circulating IgG autoantibodies that recognized type VII (show TH ELISA Kits) collagen and bound to the lamina densa of the dermal-epidermal junction[type VII (show TH ELISA Kits) collagen]

  10. Results describe the generation of a collagen VII (show TH ELISA Kits) alpha 1 hypomorphic mouse that serves as an immunocompetent animal model for dystrophic epidermolysis bullosa.

COL7A1 Antigen Profile

Antigen Summary

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Gene names and symbols associated with COL7A1

  • collagen type VII alpha 1 chain (COL7A1) antibody
  • collagen, type VII, alpha 1 (COL7A1) antibody
  • collagen type VII alpha 1 chain (col7a1) antibody
  • collagen, type VII, alpha 1 (Col7a1) antibody
  • AW209154 antibody
  • COL7A1 antibody
  • EBD1 antibody
  • EBDCT antibody
  • EBR1 antibody

Protein level used designations for COL7A1

collagen alpha-1(VII) chain , collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) , collagen, type VII, alpha 1 , alpha 1 type VII collagen , collagen alpha-1(VII) chain-like , LC collagen , collagen VII, alpha-1 polypeptide , long-chain collagen , procollagen, type VII, alpha 1

GENE ID SPECIES
403467 Canis lupus familiaris
460347 Pan troglodytes
507133 Bos taurus
709354 Macaca mulatta
100454508 Pongo abelii
100489404 Xenopus (Silurana) tropicalis
100523209 Sus scrofa
1294 Homo sapiens
12836 Mus musculus
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