anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) Antibodies

CR2 encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Additionally we are shipping Complement Component (3d/Epstein Barr Virus) Receptor 2 Kits (38) and Complement Component (3d/Epstein Barr Virus) Receptor 2 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CR2 1380 P20023
CR2 289395  
CR2 12902  
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Top anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 Antibodies at antibodies-online.com

Showing 10 out of 487 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat Un-conjugated BR, IHC (fro), FACS, IP, WB Expression of CD21/CD35 on splenic B lymphocytes. BALB/c splenocytes were stained with PE-conjugated anti-mouse CD45R/B220 mAb RA3-6B2 and either purified rat IgG2b, kappa isotype control mAb A95-1 (first panel) or purified mAb 7G6 (second panel), followed by FITC-conjugated anti-rat IgG2b mAb RG7/11.1. Flow cytometry was performed on a BD FACScan™ flow cytometry system. Expression of CD21/CD35 on splenic B lymphocytes. BALB/c splenocytes were stained with PE-conjugated anti-mouse CD45R/B220 mAb RA3-6B2 and either purified rat IgG2b, kappa isotype control mAb A95-1 (first panel) or purified mAb 7G6 (second panel), followed by FITC-conjugated anti-rat IgG2b mAb RG7/11.1. Flow cytometry was performed on a BD FACScan™ flow cytometry system. 0.5 mg Log in to see 15 to 18 Days
$337.24
Details
Mouse Rat Biotin FACS   0.1 mg Log in to see 15 to 18 Days
$280.33
Details
Cow Mouse Un-conjugated FACS, IHC (fro) 0.1 mg Log in to see 6 to 8 Days
$253.00
Details
Cow Mouse PE FACS 100 Tests Log in to see 6 to 8 Days
$357.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of CD21 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the a Western blot analysis of CD21 expression in Raji (A), KB (B), NIH3T3 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated IHC (fro), IHC (p) 1 mL Log in to see 6 to 8 Days
$962.50
Details
Horse Mouse Un-conjugated FACS Flow Cytometry: CD21 Antibody (Bu33)  - Using the Allophycocyanin direct conjugate A cell surface stain was performed on Daudi cells with CD21 Antibody (Bu33) 4APC (blue) and a matched isotype control NBP2-27287APC (orange). Cells were incubated in an antibody dilution of 0.5 ug/mL for 20 minutes at room temperature. Both antibodies were conjugated to allophycocyanin. Flow Cytometry: CD21 Antibody (Bu33)  - Using the Alexa Fluor 488 direct conjugate A surface stain was performed on human peripheral blood lymphocytes with CD21 (Bu33) antibody 4AF488 and a matched isotype control. Cells were incubated in an antibody dilution of 5 ug/mL for 20 minutes at room temperature. A co-stain was performed with NBP2-25196AF647. 0.1 mg Log in to see 7 to 9 Days
$446.35
Details
Cow Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$819.50
Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining Read the data in MicroplateReader by 450nm. Mouse splenocyte probed with Rabbit Anti-CD21/EBV receptor Polyclonal Antibody, FITC Conjugated . 100 μL Log in to see 3 to 7 Days
$317.90
Details

Top referenced anti-Complement Component (3d/Epstein Barr Virus) Receptor 2 Antibodies

  1. Mouse (Murine) Monoclonal CR2 Primary Antibody for FACS - ABIN2689089 : Ahearn, Fischer, Croix, Goerg, Ma, Xia, Zhou, Howard, Rothstein, Carroll: Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen. in Immunity 1996 (PubMed)
    Show all 20 Pubmed References

  2. Mouse (Murine) Monoclonal CR2 Primary Antibody for BR, IHC (fro) - ABIN1177262 : Masuda, Makino, Kasajima: Contribution of Thy-1-CD4+ T cells to the disorganization of lymphoid follicles in retrovirus-induced immunodeficiency syndrome, MAIDS. in Clinical immunology and immunopathology 1997 (PubMed)
    Show all 20 Pubmed References

  3. Mouse (Murine) Monoclonal CR2 Primary Antibody for BR, IHC (fro) - ABIN967384 : Axcrona, Gray, Leanderson: Regulation of B cell growth and differentiation via CD21 and CD40. in European journal of immunology 1996 (PubMed)
    Show all 21 Pubmed References

  4. Cat (Feline) Monoclonal CR2 Primary Antibody for FACS - ABIN2479266 : Ottgen: Campaign of misinformation about new nursing technician rules. in The Washington nurse 1992 (PubMed)
    Show all 4 Pubmed References

  5. African buffalo (Syncerus caffer) Monoclonal CR2 Primary Antibody for FACS - ABIN2479248 : Denham, Shimizu, Bianchi, Zwart, Carr, Parkhouse: Monoclonal antibodies recognising differentiation antigens on porcine B cells. in Veterinary immunology and immunopathology 1995 (PubMed)
    Show all 4 Pubmed References

  6. African buffalo (Syncerus caffer) Monoclonal CR2 Primary Antibody for FACS - ABIN2479250 : Tenaya, Heel, Stumbles, Wilcox: Flow cytometric analysis of lymphocyte subset kinetics in Bali cattle experimentally infected with Jembrana disease virus. in Veterinary immunology and immunopathology 2012 (PubMed)
    Show all 4 Pubmed References

  7. Cat (Feline) Monoclonal CR2 Primary Antibody for IHC (fro), FACS - ABIN2479256 : Furukawa, Bangham, Taylor, Weber, Osame: Frequent reversible membrane damage in peripheral blood B cells in human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). in Clinical and experimental immunology 2000 (PubMed)
    Show all 4 Pubmed References

  8. African buffalo (Syncerus caffer) Monoclonal CR2 Primary Antibody for FACS - ABIN2479252 : Sinkora, Stepanova, Sinkorova: Different anti-CD21 antibodies can be used to discriminate developmentally and functionally different subsets of B lymphocytes in circulation of pigs. in Developmental and comparative immunology 2013 (PubMed)
    Show all 4 Pubmed References

  9. Cat (Feline) Monoclonal CR2 Primary Antibody for FACS - ABIN2479263 : Griebel, Entrican, Rocchi, Beskorwayne, Davis: Cross-reactivity of mAbs to human CD antigens with sheep leukocytes. in Veterinary immunology and immunopathology 2007 (PubMed)
    Show all 4 Pubmed References

  10. Baboon Monoclonal CR2 Primary Antibody for FM, IHC (fro) - ABIN2689088 : Paterson, Kelleher, Amankonah, Streib, Xu, Jones, Gelfand: Model of Epstein-Barr virus infection of human thymocytes: expression of viral genome and impact on cellular receptor expression in the T-lymphoblastic cell line, HPB-ALL. in Blood 1995 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Complement Component (3d/Epstein Barr Virus) Receptor 2 Interaction Partners

Human Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) interaction partners

  1. This study shown the C3d+ microglial clusters were found in chronic but not acute multiple sclerosis.

  2. This study uncovers the origin of the effect of ionic strength on C3d-CR2 interaction and deepens the understanding of the molecular mechanism of their interaction, which is valuable for the design of vaccines and small molecule inhibitors.

  3. Binding of PF4/heparin complexes to B cells is mediated through the interaction between complement and complement receptor 2.

  4. high pERK expression and accelerated apoptosis revert within 4 weeks after beginning therapy, whereas clonal B cells unresponsive to TLR9 stimulation persist for at least 24 weeks, although they may partially rescue normal CD21 expression.

  5. Cerebrospinal fluid (CSF) soluble complement receptor 2 (sCR2) levels correlated significantly both with CSF complements C3 and C1q as well as to a disease severity measure.

  6. CR2 contributes to human Osteonecrosis of the femoral head susceptibility in Korean systemic lupus erythematosus patients.

  7. In this study, we have shown that the CR2 +24T>C polymorphism is not a risk marker for nasopharyngeal carcinoma development in the North region of Portugal.

  8. In mature B cells, CD21 transcription proceeds from a focused transcriptional start site regulated by a non-consensus TATA box, an initiator element and a downstream promoter element.

  9. Reduced expression of CD21 on CLL B-cells appears functionally relevant and was associated with poor clinical outcomes.

  10. These data suggest that rs1876453 in CR2 has long-range effects on gene regulation that decrease susceptibility to systemic lupus erythematosus.

  11. repression of the CR2/CD21 promoter can occur through one of the E-box motifs via recruitment of RP58.

  12. found that the protective CR2 genotype is correlated with lower levels CR2 mRNA as well as differences in the ratio of the long and short CR2 isoforms

  13. The paradoxical enhancement of immune responses by C3d in the absence of CD21 is due to internalization and processing of C3d into peptides that activate autoreactive CD4(+) T-helper cells.

  14. THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES

  15. Higher C3d/C3 ratios were found for current smoker, higher age, age-related macular degeneration phenotype, and the two SNPs in the C3 gene, rs6795735 and rs2230199.

  16. Authors show that expression of the Epstein-Barr virus B-cell attachment receptor, CD21, in B cells that lack this receptor results in significant changes in gene expression, both before and rapidly following EBV-CD21 interaction.

  17. Our findings implicate CR2 as a susceptibility gene for nasopharyngeal carcinoma and suggest that enhanced CR2 expression may be involved in the oncogenesis and development of nasopharyngeal carcinoma.

  18. To eradicate this virus, targeting CD21 on these EBV-infected B cells is hypothesized here.

  19. Patients with primary Sjogren's Syndrome who display high frequencies of autoreactive and unresponsive CD21-/low B cells are susceptible to developing lymphoproliferation.

  20. plasma sCD21 levels are higher, while B-cell surface CD21 expression levels are lower in B-cell chronic lymphocytic leukemia (B-CLL) patients, but not in multiple myeloma (MM) patients.

Cow (Bovine) Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) interaction partners

  1. Cattle express two major variants of the Cr2 gene representing homologues of murine CR1 and CR2, each of which is expressed in both a long and a short form.

Mouse (Murine) Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) interaction partners

  1. These results demonstrate that local expression of Cr2 in the central nervous system is part of the axotomy reaction and is suggested to modulate subsequent complement mediated effects.

  2. Immunization of Cr1KO mice with a T cell-dependent antigen resulted in the normal initial expansion of B cells with a germinal center phenotype however these cells were preferentially lost in the Cr1KO animal over time (days).

  3. This study demonistrated that receptors for complement C3 fragments (CR2/CR1) may represent a promising future approach for therapeutic immunomodulation after traumatic brain injury.

  4. Data suggest that the Cr2KO mouse thus provides a new model system for the analysis of Cr1 and Cr2 functions in the immune response of the mouse.

  5. Murine B cells predominantly express the Cr2 product from the Cr2 gene, whereas follicular dendritic cells (FDCs) almost exclusively express the Cr1 isoform generated from the Cr2 gene.

  6. Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization

  7. immune system uses three different CR1/2-mediated effector functions to generate optimal antibody responses

  8. Absence of CD21/35 protects mice from chronic wasting disease.

  9. We conclude that Cr2 regulates hippocampal neurogenesis

  10. There is a significant reduction in the numbers of both neutrophils and macrophages in cardiac isografts isolated from mice treated with either complement receptor 2-Crry or CR2-factor H.

  11. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.

  12. functionally significant phenotype for the NZM2410 Cr2 allele and strongly support its role as a lupus susceptibility gene

  13. Within the CD21 intronic control region, the formation of repeating, overlapping regulatory modules is required to coordinately control the B cell-specific expression of CD21.

  14. mouse bone marrow-derived mast cells express CD21

  15. CR2/CR1 play an unanticipated but critical role in the development of a subset of the natural Ab repertoire that has particular importance in the pathogenesis of IR injury.

  16. role of stromal cell complement receptors (CD21/CD35) and FcgammaRIIB receptors

  17. An in vivo system of intestinal ischemia-reperfusion injury reveals that mice deficient in Cr2 fail to mount an inflammatory response, as assessed by permeability index, survival, and histopathology.

  18. CD21/35 expression is critical for early protective antibody responses to lethal pathogens

  19. These results demonstrate a new B cell receptor-dependent pathway that is sufficient and perhaps necessary to provide a complement receptor 1/2 ligand that promotes efficient B cell activation.

  20. Mice deficient in CD35/CD21 showed a 67% decrease in survival compared with normal mice, suggesting that CD35/CD21 is of major importance in the control of S aureus-induced bacteremia.

Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) Antigen Profile

Protein Summary

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CR2

  • complement C3d receptor 2 (CR2) antibody
  • complement C3d receptor 2 (Cr2) antibody
  • complement receptor 2 (Cr2) antibody
  • C3DR antibody
  • Cd21 antibody
  • CD35 antibody
  • CR antibody
  • Cr-1 antibody
  • Cr-2 antibody
  • Cr1 antibody
  • CVID7 antibody
  • SLEB9 antibody

Protein level used designations for CR2

EBV receptor , complement C3d receptor , complement receptor type 2 , epstein-Barr virus receptor , complement component receptor 2 , complement receptor 1 long isoform , complement receptor 2 , complement receptor type 1 , expressed in B lymphocytes

GENE ID SPECIES
1380 Homo sapiens
407126 Bos taurus
289395 Rattus norvegicus
12902 Mus musculus
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