anti-Contactin 1 (CNTN1) Antibodies

The protein encoded by CNTN1 is a member of the immunoglobulin superfamily. Additionally we are shipping Contactin 1 Kits (34) and Contactin 1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNTN1 1272 Q12860
CNTN1 12805 P12960
CNTN1 117258 Q63198
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Top anti-Contactin 1 Antibodies at

Showing 10 out of 93 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CNTN1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: Human brain 100 μL 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-CNTN1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human brain 100 μL 2 to 3 Days
Human Goat Un-conjugated ELISA, IHC, WB   100 μg 6 to 7 Days
Human Goat Un-conjugated ELISA, IHC, WB   100 μg 6 to 7 Days
Human Rabbit Un-conjugated IHC, WB IHC on rat spinal cord (free floating section) using Rabbit antibody to contactin-1 (contactin 1, CNTN1): whole serum  at 1 : 300 dilution incubated overnight at room temperature (21C) developed with DAB/Ni. IHC on rat spinal cord (free floating section) using Rabbit antibody to contactin-1 (contactin 1, CNTN1): whole serum  at 1 : 300 dilution incubated overnight at room temperature (21C) developed with DAB/Ni. 100 μL 7 to 8 Days
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CNTN1 Antibody (Center) in A2058 cell line lysates (35µg/lane). CNTN1 (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Available
Guinea Pig Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CNTN1 / gp135 / Contactin 1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
Guinea Pig Rabbit Un-conjugated WB 100 μL 11 to 14 Days
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days

Top referenced anti-Contactin 1 Antibodies

  1. Human Polyclonal Contactin 1 Primary Antibody for IHC, WB - ABIN238957 : Chen, Nguyen, Copenhagen, Badurek, Minichiello, Ranscht, Reichardt: TrkB (tropomyosin-related kinase B) controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 (PubMed)

More Antibodies against Contactin 1 Interaction Partners

Human Contactin 1 (CNTN1) interaction partners

  1. Findings suggest that PLP1 and CNTN1 gene variations modulate specific aspects of callosal microstructure that are in line with their gene function.

  2. CNTN1 promotes growth, metastasis and invasion of Hs578T breast cancer cell line.

  3. Proteolipid protein 1 and contactin 1 gene variation modulates interhemispheric integration

  4. CNTN-1 promotes cisplatin resistance in human cisplatin-resistant lung adenocarcinoma through inducing the Epithelial-Mesenchymal Transition process by activating the PI3K/Akt signaling pathway.

  5. CNTN1 is a new gene which can be regulated by RET/PTC3 (Ret proto-oncogene and Ret-activating protein ELE1) rearrangement gene and the protein level of CNTN1 is increasing in thyroid cancer.

  6. Structurally, CASPR2 is highly glycosylated and has an overall compact architecture. CASPR2 associates with micromolar affinity with CNTN1 but, under the same conditions, it does not interact with any of the other members of the contactin family.

  7. CNTN1 promotes prostate cancer progression.

  8. High CNTN-1 expression is associated with metastasis in gastric cancer.

  9. CNTN-1 is closely related with multidrug resistance of lung adenocarcinoma.

  10. anti-CNTN1 IgG4 antibodies are associated with subacute onset of chronic inflammatory demyelinating polyneuropathy symptoms, sensory ataxia, and good response to corticosteroids.

  11. under hypoxia conditions, elevated HIF-1alpha seems to up-regulate contactin-1 expression and by this activate RhoA and facilitate migration of cancer cells.

  12. activation of AKT plays a role in contactin-1-mediated downregulation of E-cadherin.

  13. a completely novel function for F3/Contactin - modulator of neurogenesis

  14. A high expression of CNTN1 was markedly associated with the regional lymph node metastasis of patients with oral squamous cell carcinoma.

  15. The expression of CNTN-1 is upregulated in esophageal squamous cell carcinoma tissue and is related to stage and lymphatic invasion. Thus, it may be involved in the pathogenesis & progression of esophageal squamous cell carcinoma.

  16. Data revealed that knockdown of VEGFR-3 with the shRNA lentiviral vector resulted in down-regulation of the downstream neural cell adhesion molecule contactin-1 (CNTN-1).

  17. report the cocrystal structure of the carbonic anhydrase-like domain of PTPRZ bound to tandem Ig repeats of CNTN1 and binding assays to show that PTPRZ binds specifically to CNTN1 expressed at the surface of oligodendrocyte precursor cells

  18. VEGF-C mediated biological function through transcription of CNTN-1, which is implicated in tumor invasion and metastasis.

  19. F3 acts as a functional ligand for Notch during oligodendrocyte maturation.

  20. The repulsive properties of contactin may be a key factor in glioma disaggregation, and may contribute to the diffuse infiltration pattern characteristic of glioma cells in human brain.

Mouse (Murine) Contactin 1 (CNTN1) interaction partners

  1. Study confirmed that the HNK-1 epitope was primarily expressed on TNC in the embryonic day 16 mouse brain and promoted neurite outgrowth. That this signal was mediated by CNTN, which is an HNK-1-expressing neuronal receptor. These results suggest that the HNK-1 epitope is a key modifier of TNC and CNTN in the regulation of embryonic brain development.

  2. Data indicate that Contactin-1 expression is dependent upon EBF factors; Cntn1 gene belongs to the expanding regulatory cascade driven by these transcriptional regulators so that changes in its activation may contribute to the Ebf2 null mutant phenotype

  3. It plays a role in hippocampal synaptic plasticity and memory also in aged mice, suggesting that it acts on molecular pathways related to apoptosis and amyloid-beta production.

  4. The F3/contactin plays a role in promoting adult hippocampal neurogenesis and that this effect correlates with improved synaptic function and memory.

  5. Contactin-1 has roles in regulating myelination and nodal/paranodal domain organization in the central nervous system

  6. In developing cerebral cortex and basal ganglia the F3/Contactin gene is mostly activated during early commitment of neuronal precursors.

  7. The phenotype of the Cntn1 mice arises from dysfunction in the brain, spinal cord or peripheral nervous system.

  8. Data show that TAG1 and F3 act antagonistically to control SHH-induced proliferation: F3 suppresses SHH-induced GNP proliferation and induces differentiation, whereas TAG1 antagonises F3.

  9. The structural and functional properties, the mechanisms driving the regulated expression and on the developmental role of mouse F3/Contactin is reviewed.

  10. these findings indicate that precise spatio-temporal regulation of TAG-1 and F3/contactin expression is critical for normal cerebellar morphogenesis

  11. F3/contactin and caspr/paranodin traffic to the cell surface via a non-conventional pathway

  12. Deficits in sensorimotor function, homing behavior, and motor activity in transgenic F3/contactin mice indicate that the finely coordinated expression of F3/contactin is key to the functional, as well as morphological maturation of the cerebellum.

  13. These data provide evidence of a role for contactin in selectively regulating the cell surface expression and current densities of TTX-R but not TTX-S Na+ channel isoforms in nociceptive DRG neurons.

  14. Contactin-1 is a functional receptor for neuroregulatory chondroitin sulfate-E.

  15. Thus, our results suggest a contribution by DRG Na(v)1.6, and possibly Contactin to neuropathic pain in the neuroma model in mice.

Zebrafish Contactin 1 (CNTN1) interaction partners

  1. The complex regulation patterns suggest roles for Cntn1a in myelinating cells and neurons particularly in successful CNS regeneration.

Contactin 1 (CNTN1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Contactin 1 (CNTN1) Antibodies

  • contactin 1 (CNTN1) antibody
  • contactin 1 (Cntn1) antibody
  • contactin 1 L homeolog (cntn1.L) antibody
  • contactin 1a (cntn1a) antibody
  • AW495098 antibody
  • CNTN antibody
  • cntn-A antibody
  • cntn1 antibody
  • F3 antibody
  • F3/F11 antibody
  • F3cam antibody
  • F11 antibody
  • GP135 antibody

Protein level used designations for anti-Contactin 1 (CNTN1) Antibodies

contactin-1 , glycoprotein gP135 , neural cell surface protein F3 , contactin/F3/F11 , neural cell recognition molecule F11 , neural cell recognition protein , contactin 1 , Neural cell surface protein F3 , contactin-1-like , F3/F11/contactin , contactin-1a

1272 Homo sapiens
12805 Mus musculus
117258 Rattus norvegicus
281705 Bos taurus
378666 Xenopus laevis
417786 Gallus gallus
451836 Pan troglodytes
477641 Canis lupus familiaris
574365 Macaca mulatta
100049925 Equus caballus
100171863 Pongo abelii
100342120 Oryctolagus cuniculus
100386201 Callithrix jacchus
100599154 Nomascus leucogenys
100521555 Sus scrofa
100731131 Cavia porcellus
101118005 Ovis aries
353150 Danio rerio
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