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Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. Additionally we are shipping CPNE1 Proteins (15) and many more products for this protein.
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Human Polyclonal CPNE1 Primary Antibody for ELISA, WB - ABIN4300257
Zhang, Gao, Duan, He, Sun, Jiang, Duan, Zhong, Ge: Upregulation of Copine1 in trabecular meshwork cells of POAG patients: a membrane proteomics approach. in Molecular vision 2008
Human Polyclonal CPNE1 Primary Antibody for WB - ABIN2668817
Ramsey, Yeung, Stoddard, Li, Creutz, Mayo: Copine-I represses NF-kappaB transcription by endoproteolysis of p65. in Oncogene 2008
Copine I regulates tumour necrosis factor-alpha (show TNF Antibodies) receptor signaling pathways.
Copine1 is upregulated in plasma membranes of TM cells in individuals with primary open-angle glaucoma.
CPNE1 shares a promoter and 5'UTR (show UTS2R Antibodies) exons with RBM12 (show RBM12 Antibodies). This genomic structure is conserved among multiple species.
These data demonstrate that CPNE1 plays a key role in the regulation of neural stem cell functions through the activation of AKT (show AKT1 Antibodies)-mTOR (show FRAP1 Antibodies) signaling pathway during brain development.
Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins.
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