Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 Proteins (CBFA2T2)

In acute myeloid leukemia, especially in the M2 subtype, the t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities. Additionally we are shipping Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 Antibodies (91) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CBFA2T2 CBFA2T2 296293  
CBFA2T2 12396 O70374
CBFA2T2 9139 O43439
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Top Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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CBFA2T2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) Interaction Partners

Mouse (Murine) Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) interaction partners

Human Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) interaction partners

Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2) Protein Profile

Protein Summary

In acute myeloid leukemia, especially in the M2 subtype, the t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.

Gene names and symbols associated with CBFA2T2

  • CBFA2/RUNX1 translocation partner 2 (Cbfa2t2)
  • CBFA2/RUNX1 translocation partner 2 (CBFA2T2)
  • core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human) (Cbfa2t2)
  • CBFA2/RUNX1 translocation partner 2 L homeolog (cbfa2t2.L)
  • A430091M07 protein
  • C330013D05Rik protein
  • cbfa2t2-a protein
  • Cbfa2t2h protein
  • EHT protein
  • MTGR1 protein
  • p85 protein
  • XETOR protein
  • ZMYND3 protein

Protein level used designations for CBFA2T2

translocated to, 2 , myeloid translocation gene-related protein 1 , protein CBFA2T2 , CBFA2T2 identified gene homolog , MTG8-like protein , MTG8-related protein 1 , core-binding factor runt domain alpha subunit 2 translocated to 2 homolog , core-binding factor, runt domain, alpha subunit 2, translocated to, 2 homolog , ETO homolog on chromosome 20 , ETO homologous on chromosome 20 , myeloid translocation-related protein 1 , a subunit 2; translocated to, 2 , expressed during neurogenesis

GENE ID SPECIES
296293 Rattus norvegicus
419155 Gallus gallus
12396 Mus musculus
9139 Homo sapiens
379213 Xenopus laevis
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