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The protein encoded by CKM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. Additionally we are shipping Creatine Kinase, Muscle Antibodies (343) and Creatine Kinase, Muscle Proteins (42) and many more products for this protein.
Showing 10 out of 139 products:
Rat (Rattus) CKM ELISA Kit for Sandwich ELISA - ABIN578464
Jain, Suryakumar, Prasad, Ganju: Upregulation of cytoprotective defense mechanisms and hypoxia-responsive proteins imparts tolerance to acute hypobaric hypoxia. in High altitude medicine & biology 2013
Show all 4 Pubmed References
Rat (Rattus) CKM ELISA Kit for Sandwich ELISA - ABIN416341
Liu, Xu, Wang, Li, Gou, Zhang, Miao, Li: Extraocular muscle characteristics related to myasthenia gravis susceptibility. in PLoS ONE 2013
Show all 2 Pubmed References
Human CKM ELISA Kit for Sandwich ELISA - ABIN454851
Bu, Zhao, Ma, Han, Yang, Shi, Liu, Fang, Wang, Ma, Hu, Yang, Li, Liu, Nie, Zhou: Protective role of statins in patients with acute coronary syndrome aged ≥ 75 years with low LDL-C who underwent percutaneous coronary intervention. in Angiology 2015
Human CKM ELISA Kit for Sandwich ELISA - ABIN414641
Kamat, Juon, Jossen, Gajanayake, Rieben, Vögelin: Assessment of endothelium and inflammatory response at the onset of reperfusion injury in hand surgery. in Journal of inflammation (London, England) 2012
Mouse (Murine) CKM ELISA Kit for Sandwich ELISA - ABIN415530
Roncal Jimenez, Ishimoto, Lanaspa, Rivard, Nakagawa, Ejaz, Cicerchi, Inaba, Le, Miyazaki, Glaser, Correa-Rotter, González, Aragón, Wesseling, Sánchez-Lozada, Johnson: Fructokinase activity mediates dehydration-induced renal injury. in Kidney international 2014
These findings support increased CK activity as protection against ischaemia-reperfusion injury, in particular, protection via CKMT2 (show CKMT2 ELISA Kits) in a cardiac-relevant cell line, which merits further investigation in vivo.
Marathoners with a lower CKMM response after the race had a more favorable polygenic profile than runners with high serum CKMM concentrations. This might suggest a significant role of genetic polymorphisms in the levels of exertional muscle damage and rhabdomyolysis.
A positive association was found between PANSS-total and sCK [serum creatine kinase] in SzA [schizoaffective disorder] and BP-I; however, PANSS-positive scores correlated with sCK only in SzA. Serum CK may serve as a biomarker for affective exacerbation rather than psychosis.
These results demonstrate an association between physical performance measures and genetic variation in the muscle-specific creatine kinase gene (rs8111989).
troponin T and creatinine kinase isoenzyme (CK-MB) have roles in combined renal and myocardial injuries in asphyxiated infants
The serum expression levels of myocardial creatine kinase and of galectin-3 (show LGALS3 ELISA Kits) reflect the physiopathology state of children with congenital heart defects after surgical correction.
The variant rs11559024 in the CKM gene (Glu83Gly) was significantly associated with CK levels of statin users.
Based on the obtained results, it may be speculated that the CKM A/G polymorphism is not an important determinant of endurance performance level in Polish and Russian rowers.
We conclude that ILK (show ILK ELISA Kits) negatively and independently of PI3K regulated MEF2C (show MEF2C ELISA Kits) phosphorylation activity and MCK mRNA expression in C2C12 cells
The Fxn (show FXN ELISA Kits) KO/Mck mice tested from one to two months of age showed abnormal gait patterns accompanied by a loss in motor skills.
PI3K and AKT (show AKT1 ELISA Kits) regulated skeletal muscle differentiation by regulating the expression of Myogenin (show MYOG ELISA Kits) and MCK.
strong down-regulation of MCK activity contributes to F-actin instability and induces post-translational modification of alphaB-crystallin (show CRYAB ELISA Kits) and desmin (show DES ELISA Kits)
These studies indicate that the age-associated oxidative and nitrative modification of CKm results in a decrease in its activity and may cause structural changes that promote oligomerization and aggregation.
one of the consequences of M-CK and AK1 (show AK1 ELISA Kits) deficiency is hampered phosphoryl delivery to the actomyosin ATPase (show DNAH8 ELISA Kits), resulting in a loss of contractile performance.
Data show that Six4 is transcriptional regulatory element X (TrexBF) in skeletal myocytes and transactivates the muscle creatine kinase enhancer
the expression of muscle creatine kinase (MCK) gene in the heart and skeletal muscle of mice during aging
Dec proteins repressed a MyoD (show MYOD1 ELISA Kits)-activated promoter activity of muscle creatine kinase gene through class A E-box in an HDAC1 (show HDAC1 ELISA Kits)-independent manner.
Creatine kinase (CK) and adenylate kinase (AK) are especially important in facilitating energy metabolism during very high energy demands.
These data demonstrate that initial phosphocreatine hydrolysis in single skeletal muscle fibers is crucial for maintenance of sarcoplasmic reticulum Ca2 (show CA2 ELISA Kits)+ release and peak tension during a bout of repetitive tetanic contractions.
role of linker on the isolated C-terminal domain of rabbit muscle creatine kinase
when gly(268) in rabbit muscle-specific creatine kinase was substituted with asn(268), the rabbit muscle-specific CK G286N mutant specific activity at pH 8.0 and 10 degrees C was more than 2-fold higher than that in the wild-type rabbit enzyme
In addition to its role in the in vivo functions, the linker also played a crucial role in the stability and folding of CKM.
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
creatine kinase M chain
, creatine kinase M-type
, Creatine kinase, muscle form
, muscle creatine kinase
, B-creatine kinase
, Creatine kinase M chain
, Creatine kinase M-type
, creatine kinase, muscle
, creatine kinase M-type-like
, muscle creatine kinase a