Crystallin, alpha B (CRYAB) ELISA Kits

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. Additionally we are shipping CRYAB Antibodies (514) and CRYAB Proteins (30) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CRYAB 1410 P02511
CRYAB 12955 P23927
CRYAB 25420 P23928
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Top CRYAB ELISA Kits at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.12 pg/mL 12.5-800 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Chicken 5.86 pg/mL 23.44-1500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Mouse 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$606.32
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL 96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rat 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Cow 78-5000 pg/mL   96 Tests Log in to see 2 to 3 Days
$867.90
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Human
  96 Tests Log in to see 2 to 3 Days
$480.00
Details

Top referenced CRYAB ELISA Kits

  1. Human CRYAB ELISA Kit for Sandwich ELISA - ABIN2964835 : Baba, Oshitari, Yamamoto: Level of vitreous alpha-B crystallin in eyes with rhegmatogenous retinal detachment. in Graefe's archive for clinical and experimental ophthalmology 2015 (PubMed)

More ELISA Kits for CRYAB Interaction Partners

Human Crystallin, alpha B (CRYAB) interaction partners

  1. Using a combination of co-sedimentation centrifugation, viscometric assays and electron microscopy of negatively stained filaments to analyse the in vitro assembly of desmin (show DES ELISA Kits) filaments, this study shows that the binding of CRYAB to desmin (show DES ELISA Kits) is subject to its assembly status, to the subunit organization within filaments formed and to the integrity of the C-terminal tail domain of desmin (show DES ELISA Kits).

  2. Overexpression of both HSPB5 and Hsp27 significantly reduced the intracellular aggregation of alpha-synuclein.

  3. Glutathione-S-transferase (show GSTa2 ELISA Kits) - HspB1 (show HSPB1 ELISA Kits) fusion protein prevents more aggregation of malate dehydrogenase compared to glutathione-S-transferase (show GSTa2 ELISA Kits) -HspB5 fusion protein and wild type HspB1 (show HSPB1 ELISA Kits).

  4. Mechanistic studies revealed KLF4 (show KLF4 ELISA Kits) specifically bound the promoter of CRYAB and upregulated CRYAB expression in human osteosarcoma cells.

  5. mRNA levels of HSP family members (HSP70B', HSP72 (show HSPA1A ELISA Kits), HSP40/DNAJ (show DNAJB1 ELISA Kits), and HSP20 (show HSPB6 ELISA Kits)/CRYAB) are upregulated by the intracellular MMP3 (show MMP3 ELISA Kits) overload.

  6. HspB5 maybe trigger the epithelial-mesenchymal transition in colorectal cancer (CRC (show CALR ELISA Kits)) by activating the ERK (show EPHB2 ELISA Kits) signaling pathway. It is a potential tumor biomarker for CRC (show CALR ELISA Kits) diagnosis and prognosis.

  7. The CLN6 is not only a molecular entity of the anti-aggregate activity conferred by the ER manipulation using TMalphaBC, but also serves as a potential target of therapeutic interventions.

  8. Results demonstrated that CRYAA (show CRYAA ELISA Kits) rs7278468 and CRYAB rs370803064/rs387907338 are correlated with the risk and clinicopathological features of children suffering from congenital cataract.

  9. A missense mutation in alpha B-crystallin that changes proline 20 to an arginine leads to diminished anti-apoptotic activity compared with the native protein.

  10. phosphorylation finely regulates the chaperone activity of CRYAB with multipass TMPs and suggest a pivotal role for S59 in this process

Mouse (Murine) Crystallin, alpha B (CRYAB) interaction partners

  1. findings offer additional insight into the early transcriptional changes caused by Cryaa (show CRYAA ELISA Kits) and Cryab mutations associated with autosomal dominant cataracts, and indicate that the transcript levels of certain genes are affected by the expression of mutant alpha-crystallin in vivo

  2. desmin and alphaBeta-crystallin are localized at sarcoplasmic reticulum (SR)-mitochondria-associated membranes (MAMs), where they interact with VDAC, Mic60 - the core component of mitochondrial contact site and cristae organizing system (MICOS) complex - and ATP synthase, suggesting that these associations could be crucial in mitoprotection at different levels.

  3. This study demonstrated that HspB5 mRNA localization in myelin-enriched white and gray matter

  4. alphaB-crystallin is an important regulator of epithelial-mesenchymal transition, acting as a molecular chaperone (show HSP90AA1 ELISA Kits) for SMAD4 (show SMAD4 ELISA Kits) and as its potential therapeutic target for preventing subretinal fibrosis development in neovascular age-related macular degeneration

  5. It is a non-Hsp gene, which is essential for HSF1 (show HSF1 ELISA Kits)-mediated maintenance of whole body homeostasis.

  6. A previously unrecognized link between c-Jun (show JUN ELISA Kits) and Nrf2 (show NFE2L2 ELISA Kits) transcription factors and redox-induced CRYAB expression in muscle cells.

  7. CryAB protects decidualization against stress conditions.

  8. TNF-alpha (show TNF ELISA Kits)-induced endothelial adhesion molecule (show NCAM1 ELISA Kits) expression is reduced in inflamed vessels of alphaB-crystallin deficient mice, and leukocyte rolling velocity and IkappaB levels are increased.

  9. Study shows that overexpression of Bcl-2 (show BCL2 ELISA Kits) is sufficient to reduce the levels and overall architecture of protein deposition in the transgenic CryABR120G/Bcl-2 (show BCL2 ELISA Kits) hearts.

  10. alphaB-crystallin is over-expressed in fibrotic lung tissue and favors TGF-beta1 (show TGFB1 ELISA Kits) pathway via its role in modulating the cellular localization of Smad4 (show SMAD4 ELISA Kits).

Cow (Bovine) Crystallin, alpha B (CRYAB) interaction partners

  1. The alphaB-crystallin content of bovine type I muscle fibers is quantitatively similar to that in the predominantly type I fibers of rat soleus muscle.

  2. In the presence of alpha-crystallin or GroEL the kinetic of GAPDH (show GAPDH ELISA Kits) aggregation is changed from the diffusion-limited cluster-cluster aggregation to the reaction-limited cluster-cluster aggregation.

  3. one of the functions of alphaB-crystallin is to bind microtubules via microtubule binding proteins and to give the MTs (show NEU2 ELISA Kits) resistance to disassembly

  4. The study provides evidence for the regulation of the chaperone activity of alphaB-crystallin by phosphorylation and indicates that this may play an important role in alleviating the pathogenic effects associated with protein conformational diseases.

Pig (Porcine) Crystallin, alpha B (CRYAB) interaction partners

  1. This study clearly demonstrated that both the length and electrostatic charge of the COOH-terminal segment play crucial roles in governing the structural stability and chaperone activity of alphaB-crystallin.

CRYAB Antigen Profile

Antigen Summary

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases\; a missense mutation cosegregated in a family with a desmin-related myopathy.

Gene names and symbols associated with Crystallin, alpha B (CRYAB) ELISA Kits

  • crystallin alpha B (CRYAB) antibody
  • crystallin, alpha B (Cryab) antibody
  • hypothetical protein (ZK1128.7) antibody
  • crystallin alpha B (Cryab) antibody
  • AACRYA antibody
  • CMD1II antibody
  • Crya-2 antibody
  • Crya2 antibody
  • CRYAB antibody
  • CTPP2 antibody
  • CTRCT16 antibody
  • HspB5 antibody
  • MFM2 antibody

Protein level used designations for Crystallin, alpha B (CRYAB) ELISA Kits

alpha-crystallin B chain , heat shock protein beta-5 , heat-shock 20 kD like-protein , renal carcinoma antigen NY-REN-27 , rosenthal fiber component , P23 , alpha B-crystallin , alpha(B)-crystallin , crystallin, alpha 2 , Crystallin, alpha polypeptide 2 , hypothetical protein , crystallin, alpha B , alpha B crystallin , alpha-B-crystallin , alphaB-crystallin , crystallin, alpha polypeptide 2 , Alpha(B)-crystallin , Alpha-crystallin B chain

GENE ID SPECIES
1410 Homo sapiens
12955 Mus musculus
25420 Rattus norvegicus
191528 Caenorhabditis elegans
396089 Gallus gallus
451543 Pan troglodytes
479441 Canis lupus familiaris
497274 Ovis aries
100009295 Oryctolagus cuniculus
100172850 Pongo abelii
100306972 Cavia porcellus
281719 Bos taurus
100519789 Sus scrofa
710747 Macaca mulatta
791109 Ornithorhynchus anatinus
101827485 Mesocricetus auratus
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