anti-Cyclic Nucleotide Gated Channel alpha 2 (CNGA2) Antibodies

The protein encoded by CNGA2 represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. Additionally we are shipping Cyclic Nucleotide Gated Channel alpha 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNGA2 25411 Q00195
CNGA2 1260 Q16280
CNGA2 12789 Q62398
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Top anti-Cyclic Nucleotide Gated Channel alpha 2 Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of CNGA2 expression in HepG2 (A), A431 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using CNGA2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated IHC (p), WB CNGA2 Antibody (N-term) (ABIN658407) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the CNGA2 antibody detected the CNGA2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ELISA, IF, WB Western Blot (WB) analysis of specific cells using CNG-2 Polyclonal Antibody. 100 μL Log in to see Available
$363.46
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of CNGA2 Antibody (N-term) (ABIN651051) in K562 cell line lysates (35 µg/lane). CNGA2 (arrow) was detected using the purified polyclonal antibody. CNGA2 Antibody (N-term) (ABIN651051) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-CNGA2 Polyclonal Antibody, Unconjugated (ABIN677258) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 200 μL Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$416.90
Details
Human Rabbit Un-conjugated ICC, IHC, IHC (p), WB   100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: 293T B: A431 , C: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded SG xenograft , using CNGA2, antibody at 1:500 dilution. 100 μL Log in to see 3 to 4 Days
$466.18
Details

Top referenced anti-Cyclic Nucleotide Gated Channel alpha 2 Antibodies

  1. Mouse (Murine) Polyclonal CNGA2 Primary Antibody for IHC (p), WB - ABIN658407 : Matsuo, Hattori, Asaba, Inoue, Kanomata, Kikusui, Kobayakawa, Kobayakawa: Genetic dissection of pheromone processing reveals main olfactory system-mediated social behaviors in mice. in Proceedings of the National Academy of Sciences of the United States of America 2015 (PubMed)

More Antibodies against Cyclic Nucleotide Gated Channel alpha 2 Interaction Partners

Human Cyclic Nucleotide Gated Channel alpha 2 (CNGA2) interaction partners

  1. The studies findings provides strong support for role of CNGA2 gene with pathogenicity of isolated congenital anosmia in humans. Together, these results indicate that mutations in key olfactory signaling pathway genes are responsible for human disease.

  2. Identification of a novel X-linked stop mutation in CNGA2 (c.634C>T, p.R212*) in two brothers with isolated congenital anosmia.

  3. The results showed that it is predominantly the charge of the E342 residue in the P-loop, rather than the pore helix dipoles, which controls the cation-anion selectivity of the CNGA2 channel.

Cow (Bovine) Cyclic Nucleotide Gated Channel alpha 2 (CNGA2) interaction partners

  1. CNGA2 channels play a key role in adenosine-induced endothelial Ca(2+) influx and vasorelaxation

  2. Mediates epinephrine-induced endothelial calcium influx and subsequent vascular dilation.

Mouse (Murine) Cyclic Nucleotide Gated Channel alpha 2 (CNGA2) interaction partners

  1. In Cnga2 knock-out mice there was an overproduction of Amyloid beta protein, tau hyper-phosphorylation, and behavioral abnormalities.

  2. This study found that Cnga2 mice showed increased anxiety- and depressive-like behaviors than their wide type siblings.

  3. Retinoic acid receptor and CNGA2 channel signaling are part of a regulatory feedback loop controlling axonal convergence and survival of olfactory sensory neurons.

  4. CNGA2 channels contribute to ATP-induced non-capacitative calcium influx in vascular endothelial cells. It is likely that ATP acts through P2Y(1)receptors and adenylyl cyclases to stimulate CNGA2.

  5. important for odor discrimination and adaptation in behaving mice

  6. Several odorants including putative pheromones can be detected and discriminated by CNGA2 knock-out mice behaviorally. These odors elicit responses in the olfactory epithelium, main olfactory bulb, and olfactory (piriform) cortex

  7. Mice lacking functional CNGA2, which is required for odor-evoked MOE signaling, fail to mate or fight, suggesting a broad and essential role for the MOE in regulating these behaviors.

  8. Function in the nose is unique to the main population of olfactory sensory neurons.

  9. CNGA2 channels are not necessary for either the response of GnRH-1 neurons to cAMP increases or the basal rhythmic activity of GnRH-1 neurons.

  10. CNGA2 channels play a key role in adenosine-induced endothelial Ca(2+) influx and vasorelaxation

  11. Mediates epinephrine-induced endothelial calcium influx and subsequent vascular dilation.

Cyclic Nucleotide Gated Channel alpha 2 (CNGA2) Antigen Profile

Protein Summary

The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation.

Gene names and symbols associated with CNGA2

  • cyclic nucleotide gated channel alpha 2 (Cnga2) antibody
  • cyclic nucleotide gated channel alpha 2 (CNGA2) antibody
  • cyclic nucleotide gated channel alpha 2 (cnga2) antibody
  • Cnca antibody
  • CNCA1 antibody
  • CNCG2 antibody
  • Cncg4 antibody
  • CNG2 antibody
  • CNGA2 antibody
  • OCNC1 antibody
  • OCNCa antibody
  • OCNCALPHA antibody
  • OLFCH antibody

Protein level used designations for CNGA2

CNG channel alpha-2 , CNG-2 , CNG2 , cyclic nucleotide gated channel 4 , cyclic nucleotide-gated cation channel 2 , cyclic nucleotide-gated channel alpha-2 , cyclic nucleotide-gated olfactory channel , cyclic nucleotide-gated olfactory channel subunit OCNC1 , cyclic-nucleotide-gated cation channel 2 , cyclic-nucleotide-gated olfactory channel , cAMP-gated channel , cyclic nucleotide gated channel alpha 2

GENE ID SPECIES
25411 Rattus norvegicus
1260 Homo sapiens
100009269 Oryctolagus cuniculus
407172 Bos taurus
473822 Pan troglodytes
503867 Danio rerio
612414 Canis lupus familiaris
771609 Gallus gallus
12789 Mus musculus
100543783 Meleagris gallopavo
100590103 Nomascus leucogenys
100069276 Equus caballus
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