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The protein encoded by CCNL2 belongs to the cyclin family. Additionally we are shipping Cyclin L2 Kits (12) and Cyclin L2 Proteins (4) and many more products for this protein.
Showing 10 out of 48 products:
Human Polyclonal Cyclin L2 Primary Antibody for ELISA, IP - ABIN6655712
Kren, Unger, Abedin, Vogel, Henzler, Ahmed, Trembley: Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy. in Breast cancer research : BCR 2015
Show all 2 Pubmed References
Human Polyclonal Cyclin L2 Primary Antibody for IP, WB - ABIN257743
Kyei, Cheng, Ramani, Ratner: Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance. in Cell host & microbe 2015
Therefore, cyclin L2-mediated control of SAMHD1 levels in macrophages supports HIV-1 replication.
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome.
characterize cyclin L2 as a highly mobile component of nuclear speckles and suggest that DYRK1A may regulate splicing by phosphorylation of cyclin L2
represents a new member of the cyclin family, which might regulate the transcription and RNA processing of certain apoptosis-related factors
Data show that a green fluorescent protein (GFP) fusion protein of cyclin L1, in contrast to cyclin L2, was not mobile within the nucleus of living COS7 cells.
CDK11(p110) interacts physically and functionally with cyclin Lalpha and -beta isoforms and SR proteins to regulate splicing.
These data suggest that overexpression of CCNL2 inhibited proliferation and differentiation of mouse embryonic carcinoma P19 cells and induced them to undergo apoptosis, possibly through the Wnt signal transduction pathway.
The protein encoded by this gene belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, cyclin M
, paneth cell-enhanced expression protein
, cyclin S
, cyclin Ania-6b
, paneth cell enhanced expression