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The protein encoded by CDK20 contains a kinase domain most closely related to the cyclin-dependent protein kinases. Additionally we are shipping Cyclin-Dependent Kinase 20 Antibodies (104) and Cyclin-Dependent Kinase 20 Proteins (12) and many more products for this protein.
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Results delineate an immunosuppressive mechanism of the hepatoma-intrinsic CCRK signalling and highlight an overexpressed kinase target whose inhibition might empower hepatocellular carcinoma immunotherapy
A CCRK-EZH2 (show EZH2 ELISA Kits) epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patient.
In glioblastoma cells with deregulated high levels of CCRK, its depletion restores cilia through ICK (show ICK ELISA Kits) and an ICK (show ICK ELISA Kits)-related kinase MAK (show MAK ELISA Kits), thereby inhibiting glioblastoma cell proliferation.
Data indicate that expression of ERAS, LHX1 (show LHX1 ELISA Kits), and CCRK is increased in aggressive subgroups of medulloblastomas.
Cell cycle-related kinase is a direct androgen receptor (show AR ELISA Kits)-regulated gene that drives beta-catenin (show CTNNB1 ELISA Kits)/T cell factor-dependent hepatocarcinogenesis
results suggest for the first time that CCRK is involved in colorectal cancer carcinogenesis and G1/S cell cycle transition by regulating Cdk2 (show CDK2 ELISA Kits), cyclin E (show CCNE1 ELISA Kits) and Rb.
identification of p42 (show EPB42 ELISA Kits), a novel cyclin-dependent kinase (show CDK1 ELISA Kits)-activating kinase (CAK (show CCNH ELISA Kits)) activity in human cells; p42 (show EPB42 ELISA Kits) is essential for the phosphorylation of Thr (show TRH ELISA Kits)-160 and activation of CDK2 (show CDK2 ELISA Kits) and is indispensable for cell growth
Depletion of PNQALRE by >80% due to RNA interference (RNAi) impairs cell proliferation, but fails to arrest the cell cycle at a discrete point.
Overexpression of CCRK is associated with ovarian carcinoma.
heart expresses a splice variant of CCRK, which promotes cardiac cell growth and survival; differs from the generic isoform in protein-protein interactions, substrate specificity and regulation of cell cycle; and is down-regulated in heart failure
The protein encoded by this gene contains a kinase domain most closely related to the cyclin-dependent protein kinases. The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
, CDK-activating kinase p42
, cell cycle-related kinase
, cell division protein kinase 20
, cyclin-dependent protein kinase H
, cyclin-kinase-activating kinase p42
, cell cycle related kinase
, cell cycle-related kinase cardiac
, CDK-related protein kinase PNQLARE
, cyclin-dependent kinase 20
, LOW QUALITY PROTEIN: cyclin-dependent kinase 20