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CCBL1 encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. Additionally we are shipping CCBL1 Kits (14) and CCBL1 Proteins (10) and many more products for this protein.
Showing 10 out of 76 products:
Human Polyclonal CCBL1 Primary Antibody for ELISA - ABIN548068
Cooper: The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. in Neurochemistry international 2004
Human Polyclonal CCBL1 Primary Antibody for ICC, IF - ABIN4301915
van Steenbeek, Van den Bossche, Grinwis, Kummeling, van Gils, Koerkamp, van Leenen, Holstege, Penning, Rothuizen, Leegwater, Spee: Aberrant gene expression in dogs with portosystemic shunts. in PLoS ONE 2013
One is the native structure with the cofactor in the PLP form bound to Lys247 with the highest resolution yet available for KAT-I at 1.28 A resolution, and the other with the general PLP-dependent aminotransferase inhibitor, aminooxyacetate (AOAA) covalently bound to the cofactor at 1.54 A.
KAT I inhibited by equimolar tryptophan and half-life is 69.7 minutes at 65 degree C.
Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections.
CH(3)Hg-S-Cys and Cys-S-Hg-S-Cys are substrates and reversible inhibitors of GTK.
major biological roles of glutamine transaminase K are to maintain low levels of phenylpyruvate and to close the methionine salvage pathway--REVIEW
We found elevated cerebellar KAT-1 activities in post-mortem brain samples from schizophrenic versus normal individuals.
alpha-keto acids generated by transamination/l-amino acid oxidase activity of the two catechol cysteine S-conjugates are unstable
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
, cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)
, glutamine transaminase K
, glutamine--phenylpyruvate transaminase
, kynurenine aminotransferase I
, kynurenine--oxoglutarate transaminase 1
, kynurenine--oxoglutarate transaminase I
, beta-lysase, kidney
, cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)
, glutamine-phenylpyruvate aminotransferase
, kyneurenine aminotransferase
, cysteine conjugate-beta lyase 1
, kynurenine aminotransferase/glutamine transaminase K
, kynurenine--oxoglutarate transaminase 1, mitochondrial