Cysteinyl-tRNA Synthetase Proteins (CARS)

CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Additionally we are shipping Cysteinyl-tRNA Synthetase Antibodies (68) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CARS 833 P49589
CARS 27267 Q9ER72
Rat CARS CARS 293638  
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Top Cysteinyl-tRNA Synthetase Proteins at

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days

CARS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Cysteinyl-tRNA Synthetase (CARS) Interaction Partners

Human Cysteinyl-tRNA Synthetase (CARS) interaction partners

  1. Four single nucleotide polymorphisms (SNPs) of CARS were significantly associated with gastric cancer risk in both the discovery stage and the validation stage

  2. The risk (G and C) and non-risk (C and T) allele frequencies of the SNPs at the rs1888747 and rs739401 loci of FRMD3 and CARS, respectively, did not differ significantly between the diabetics with (case) and without (control) nephropathy (P > 0.05).

  3. Loss of CARS, the cysteinyl-tRNA synthetase, suppresses ferroptosis induced by erastin, which inhibits the cystine-glutamate antiporter known as system xc(-).

  4. CARS is a novel fusion partner of anaplastic lymphoma kinase in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor cases.

  5. Specificity of anticodon recognition by human CysRS is higher than that of its bacterial counterparts.

Cysteinyl-tRNA Synthetase (CARS) Protein Profile

Protein Summary

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with CARS

  • cysteinyl-tRNA synthetase (CARS)
  • cysteinyl-tRNA synthetase (cars)
  • Cysteinyl-tRNA synthetase (CysRS)
  • cysteine--tRNA ligase (cysS)
  • cysteinyl-tRNA synthetase (cysS)
  • cysteine--tRNA ligase (APH_RS02395)
  • cysteine-tRNA ligase (mcysS)
  • cysteine-tRNA ligase (cysS)
  • Cysteinyl-tRNA synthetase, class Ia family protein (SYCO ARATH)
  • Cysteinyl-tRNA synthetase, class Ia family protein (AT3G56300)
  • Cysteinyl-tRNA synthetase, class Ia family protein (AT5G38830)
  • cysteinyl-tRNA synthetase CysS (cysS)
  • cysteinyl-tRNA synthetase S homeolog (cars.S)
  • cysteinyl-tRNA synthetase (Cars)
  • BA0089 protein
  • BcDNA:LD21177 protein
  • CA3 protein
  • CARS protein
  • CARS1 protein
  • CG8431 protein
  • CRS protein
  • CYSRS protein
  • DDBDRAFT_0187313 protein
  • DDBDRAFT_0215191 protein
  • DDBDRAFT_0231318 protein
  • DDBDRAFT_0231320 protein
  • DDB_0187313 protein
  • DDB_0215191 protein
  • DDB_0231318 protein
  • DDB_0231320 protein
  • Dmel\\CG8431 protein
  • K15E6.3 protein
  • K15E6_3 protein
  • MGC:11246 protein
  • sb:cb71 protein
  • T16B12.16 protein

Protein level used designations for CARS

cysteinyl-tRNA synthetase, cytoplasmic , cysteinyl-tRNA synthetase , cysRS , cysteine--tRNA ligase, cytoplasmic , Aats-cys-PA , CG8431-PA , cysteine-tRNA ligase , cysteine tRNA ligase 1, cytoplasmic , cysteine translase

515715 Bos taurus
368284 Danio rerio
450962 Pan troglodytes
475998 Canis lupus familiaris
496832 Xenopus (Silurana) tropicalis
706502 Macaca mulatta
36784 Drosophila melanogaster
1085927 Bacillus anthracis str. Ames
1209397 Coxiella burnetii RSA 493
2799423 Listeria monocytogenes serotype 4b str. F2365
3229029 Dehalococcoides ethenogenes 195
3728054 Carboxydothermus hydrogenoformans Z-2901
3930041 Anaplasma phagocytophilum str. HZ
8620927 Dictyostelium discoideum AX4
8625991 Dictyostelium discoideum AX4
817673 Arabidopsis thaliana
824797 Arabidopsis thaliana
833874 Arabidopsis thaliana
1169564 Shewanella oneidensis MR-1
3171872 Anaplasma marginale str. St. Maries
3231406 Campylobacter jejuni RM1221
380479 Xenopus laevis
423086 Gallus gallus
833 Homo sapiens
27267 Mus musculus
293638 Rattus norvegicus
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