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CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Additionally we are shipping Cysteinyl-tRNA Synthetase Antibodies (58) and and many more products for this protein.
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Four single nucleotide polymorphisms (SNPs) of CARS were significantly associated with gastric cancer risk in both the discovery stage and the validation stage
The risk (G and C) and non-risk (C and T) allele frequencies of the SNPs at the rs1888747 and rs739401 loci of FRMD3 and CARS, respectively, did not differ significantly between the diabetics with (case) and without (control) nephropathy (P > 0.05).
Loss of CARS, the cysteinyl-tRNA synthetase, suppresses ferroptosis induced by erastin, which inhibits the cystine-glutamate antiporter known as system xc(-).
CARS is a novel fusion partner of anaplastic lymphoma kinase in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor cases.
Specificity of anticodon recognition by human CysRS is higher than that of its bacterial counterparts.
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.
cysteinyl-tRNA synthetase, cytoplasmic
, cysteinyl-tRNA synthetase
, cysteine--tRNA ligase, cytoplasmic
, cysteine-tRNA ligase
, cysteine tRNA ligase 1, cytoplasmic
, cysteine translase