Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) ELISA Kits

CFTR encodes a member of the ATP-binding cassette (ABC) transporter superfamily. Additionally we are shipping CFTR Antibodies (357) and CFTR Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CFTR 1080 P13569
CFTR 12638 P26361
CFTR 24255 P34158
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Top CFTR ELISA Kits at antibodies-online.com

Showing 10 out of 43 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 7 pg/mL 28-1800 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Dog 4.69 pg/mL 18.75-1200 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Rabbit 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rat 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Mouse 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

More ELISA Kits for CFTR Interaction Partners

Human Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. In this report we target premature termination codons (PTCs) in messages encoding both a fluorescent reporter protein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein transiently transfected into human epithelial cells. We demonstrate that while on-target editing is efficient, off-target editing is extensive, both within the targeted message and across the entire transcriptome of the transfected

  2. Studies indicate that the most common mutation in cystic fibrosis (show S100A8 ELISA Kits) (CF), the deletion of a phenylalanine at position 508, involves dramatic alterations of the cystic fibrosis transmembrane conductance regulator (CFTR) traffic, processing and folding.

  3. CFTR silencing results in lipid homeostasis disruption and mitochondrial dysfunction in intestinal epithelial cells.

  4. Roles of CFTR in fundamental cellular processes including transformation, survival, proliferation, migration, invasion and epithelial-mesenchymal transition in cancer cells, highlighting the signaling pathways involved. Finally, the association of CFTR expression levels with patient prognosis, and the potential of CFTR as a cancer prognosis indicator in human malignancies will be discussed. [review]

  5. CFTR exhibited an inhibitory role in the malignancy of lung adenocarcinoma A549 cells

  6. in Caco-2 CFTR-shRNA cells, the EGFR (show EGFR ELISA Kits) ligand EREG (show EREG ELISA Kits) is overexpressed due to an active IL-1beta (show IL1B ELISA Kits) autocrine loop that indirectly activates EGFR (show EGFR ELISA Kits), constituting new signaling effectors for the CFTR signaling pathway, downstream of CFTR, Cl(-) , and IL-1beta (show IL1B ELISA Kits).

  7. The reduced CFTR expression and the mitochondrial damage induced by Cigarette Smoke Extract (CSE) could not be normalized by N-acetylcysteine (NAC (show NLRP1 ELISA Kits)) treatment, evidencing the need for a more specific reagent. In conclusion, CSE causes a sterile proinflammatory state and mitochondrial damage in Calu (show CALU ELISA Kits)-3 cells that was partially recovered by NAC (show NLRP1 ELISA Kits) treatment.

  8. Study found a significant association of CFTR gene c.1210-34TG [12]/c.1210-34TG [13] - c.1210-12[5] -V470 allele with congenital bilateral absence of the vas (show AVP ELISA Kits) deferens in Indian men.

  9. CFTR expression level is relevant to fecundity of healthy couples and shows potential predictive capacity of fecundity.

  10. To expand the computational strategy designed when studying XIAP (show XIAP ELISA Kits), we have applied the molecular modeling tools to a list of 140 variants seen in CFTR associated with cystic fibrosis (show S100A8 ELISA Kits), and a list of undiagnosed variants in 17 different genes. Graphical abstract XIAP (show XIAP ELISA Kits) in Caspase 3 (show CASP3 ELISA Kits) and NOD2 (show NOD2 ELISA Kits) signaling pathways.

Xenopus laevis Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Study conclude that when both CFTR and NPT2a are expressed in X. laevis oocytes, CFTR confers to NPT2a a cAMPi-dependent trafficking to the membrane.

  2. NDPK-A (show NME1 ELISA Kits) exists in a functional cellular complex with AMPK (show PRKAA2 ELISA Kits) and CFTR in airway epithelia, and NDPK-A (show NME1 ELISA Kits) catalytic function is required for the AMPK (show PRKAA2 ELISA Kits)-dependent regulation of CFTR

  3. This study discovers an essential role of CFTR in mediating the retinoic acid-dependent signaling for stem cell differentiation and embryonic development (show PLCG1 ELISA Kits).

  4. wild-type CFTR channel gating cycle is essentially irreversible and tightly coupled to the ATPase (show DNAH8 ELISA Kits) cycle, and that this coupling is completely destroyed by the NBD2 Walker B mutation D1370N but only partially disrupted by the NBD1 Walker A mutation K464A.

  5. The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that belongs to the superfamily of ATP binding cassette (ABC (show ABCB6 ELISA Kits)) transporters.

  6. These data suggest that the Xenopus P2Y1 receptor (show P2RY1 ELISA Kits) can increase both cyclic AMP/protein kinase A and calcium/protein kinase C (show PKC ELISA Kits) levels and that the PKC (show PKC ELISA Kits) pathway is involved in CFTR activation via potentiation of the PKA pathway.

Mouse (Murine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Results show that CFTR channels are present in alpha cells and act as important negative regulators of cAMP-enhanced glucagon (show GCG ELISA Kits) secretion through effects on alpha cell membrane potential. These data support that loss-of-function mutations in CFTR contributes to dysregulated glucagon (show GCG ELISA Kits) secretion in Cystic Fibrosis (show S100A8 ELISA Kits)-related diabetes.

  2. these results demonstrate that CFTR prevents inflammation and atherogenesis via inhibition of NFkappaB and MAPKs activation

  3. CFTR physically interacts with beta-catenin (show CTNNB1 ELISA Kits), defect of which leads to premature degradation of beta-catenin (show CTNNB1 ELISA Kits) and suppressed activation of beta-catenin (show CTNNB1 ELISA Kits) signaling.

  4. CFTR attaches tumor suppressor PTEN to the membrane and promotes anti Pseudomonas aeruginosa immunity.

  5. Our studies reveal a novel function for CFTR in antiviral immunity and demonstrate that the DeltaF508 mutation in cftr is coupled to an impaired adaptive immune response. This important insight could open up new approaches for patient care and treatment.

  6. a new and more convenient approach, based on in vivo imaging analysis, has been set up to evaluate the inflammatory response in the lung of CFTR-deficient (CF) mice, a murine model of cystic fibrosis (show S100A8 ELISA Kits).

  7. results reveal that by potentiating adenosine triphosphate-sensitive K+ (KATP) channel, cystic fibrosis transmembrane conductance regulator CFTR acts as a glucose-sensing negative regulator of glucagon (show GCG ELISA Kits) secretion in alpha cells

  8. This study demonstrates that CFTR plays an important role in tenogenic differentiation and tendon regeneration by inhibiting the beta-catinin/pERK1/2 signaling pathway.

  9. CFTR is a tumor suppressor gene in murine and human colorectal cancer

  10. Insulin (show INS ELISA Kits) stimulation of Akt1 (show AKT1 ELISA Kits) and Akt2 (show AKT2 ELISA Kits) signaling in Cystic fibrosis (show S100A8 ELISA Kits) airway cells was diminished compared with that observed in airway cells expressing wild-type CFTR.

Pig (Porcine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Results suggest that acetylcholine does not regulate the activity of the CFTR in tracheal epithelia of pigs which opposes observation from studies using mice airway epithelium.

  2. Expression of CFTR-F508del interferes with smooth muscle cell calcium handling and decreases aortic responsiveness.

  3. Pseudomonas aeruginosa and other bacteria into the lumen of intact isolated swine tracheas triggers CFTR-dependent airway surface liquid secretion by the submucosal glands.

  4. TGF-beta1 (show TGFB1 ELISA Kits), via TGF-beta1 (show TGFB1 ELISA Kits) receptor I and p38 MAPK (show MAPK14 ELISA Kits) signaling, reduces CFTR expression to impair CFTR-mediated anion secretion, which would likely compound the effects associated with mild CFTR mutations and ultimately would compromise male fertility.

  5. The esophageal submucosal glands (SMG) secrete HCO(3)(-) and mucus into the esophageal lumen, where they contribute to acid clearance and epithelial protection. We investigated the presence of CFTR, its involvement in the secretion process, and the effect of cAMP on HCO3 secretion in this tissue. This is the first report on the presence of CFTR channels in the esophagus.

  6. data suggest that loss of CFTR directly alters Schwann cell function and that some nervous system defects in people with cystic fibrosis (show S100A8 ELISA Kits) are likely primary

  7. The data suggest, that during bacterial infections and resulting release of proinflammatory cytokines, the glands are stimulated to secrete fluid, and this response is mediated by cAMP-activated CFTR.

  8. CFTR is required for maximal liquid absorption by lung alveoli under cAMP stimulation

  9. These findings reveal differences between nasal and tracheal glands, show defective fluid secretion in nasal glands of cystic fibrosis (show S100A8 ELISA Kits) pigs, reveal some spared function in the DeltaF508 vs. null piglets.

  10. causal link between CFTR mutations and partial or total vas (show AVP ELISA Kits) deferens and/or epididymis atresia at birth

Cow (Bovine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. conserved CFTR sequences between species are examined for potential regulatory elements. Regions of introns 2, 3, 10, 17a, 18, and 21 and 3' flanking sequence corresponding to human CFTR DNase I (show DNASE1 ELISA Kits) hypersensitive sites showed high homology in cow and pig.

Guinea Pig Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Results demonstrate functional coupling between Cftr and Slc26a6-like Cl(-)/HCO(3)(-) exchange activity in apical membrane of guinea pig pancreatic interlobular duct.

Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Molecular dynamics of the cryo-EM CFTR structure

  2. Study presents the structure of zebrafish CFTR in the phosphorylated, ATP-bound conformation, determined by cryoelectron microscopy to 3.4 A resolution. Comparison of the two conformations shows major structural rearrangements leading to channel opening.

  3. Study determined the structure of the zebrafish CFTR by electron cryo-microscopy to 3.7 A resolution; shares 55% sequence identity with human CFTR, and 42 of the 46 cystic-fibrosis (show S100A8 ELISA Kits)-causing missense mutational sites are identical.

  4. Cftr mutant zebrafish develops pancreatic destruction similar to cystic fibrosis (show S100A8 ELISA Kits) of the human pancreas.

CFTR Antigen Profile

Antigen Summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.

Gene names and symbols associated with CFTR

  • cystic fibrosis transmembrane conductance regulator (CFTR) antibody
  • cystic fibrosis transmembrane conductance regulator (cftr-A) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (CFTR) antibody
  • cystic fibrosis transmembrane conductance regulator (Cftr) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (cftr) antibody
  • abc35 antibody
  • abcc7 antibody
  • AW495489 antibody
  • CF antibody
  • CFTR antibody
  • cftr/mrp antibody
  • dJ760C5.1 antibody
  • mrp7 antibody
  • RGD1561193 antibody
  • si:dkey-270i2.2 antibody
  • tnr-cftr antibody
  • xcftr antibody

Protein level used designations for CFTR

cAMP-dependent chloride channel , channel conductance-controlling ATPase , cystic fibrosis transmembrane conductance regulator , cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) , cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) , ATP-binding cassette sub-family C member 7 , ATP-binding cassette transporter sub-family C member 7 , ATP-binding cassette, subfamily c, member 7 , cystic fibrosis transmembrane conductance regulator homolog , cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7 , CFTR chloride channel , chloride channel , CFTR cAMP-dependent chloride channel protein , Channel conductance-controlling ATPase , abcc7

GENE ID SPECIES
1080 Homo sapiens
373725 Xenopus laevis
780954 Monodelphis domestica
100137161 Nomascus leucogenys
12638 Mus musculus
24255 Rattus norvegicus
100049619 Gallus gallus
492302 Canis lupus familiaris
100071259 Equus caballus
403154 Sus scrofa
281067 Bos taurus
443347 Ovis aries
100009471 Oryctolagus cuniculus
463674 Pan troglodytes
100137035 Pongo abelii
100719898 Cavia porcellus
100381094 Xenopus laevis
100126675 Papio anubis
559080 Danio rerio
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