anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) Antibodies

CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2B6 Kits (15) and CYP2B6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP2B6 1555 P20813
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Top anti-CYP2B6 Antibodies at

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYP2B6 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate Host:  Mouse  Target Name:  CYP2B10  Sample Tissue:  Mouse Pancreas  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2B6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cytochrome P450 2B6 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytochrome P450 2B6 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of CYP2B6 Antibody (Center) (ABIN655056) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabilized MCF-7 (human breast cancer cell line) cells labeling Pdx1 with ABIN2844685 at 1/25 dilution, followed by Dylight® 488-conjugated goat anti-rabbit IgG (NK179883) secondary antibody at 1/200 dilution (green). Immunofluorescence image showing endosomes staining on MCF-7 cell line. Cytoplasmic actin is detected with Dylight® 554 Phalloidin (PD18466410) at 1/100 dilution (red). The nuclear counter stain is DAPI (blue). Dilution: 1:25 400 μL Log in to see 10 to 11 Days
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using CYP2B6 antibody (ABIN5997556) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human lung using CYP2B6 antibody (ABIN5997556) at dilution of 1/100 (40x lens). 100 μL Log in to see 11 to 18 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-CYP2B6 mouse monoclonal antibody (ABIN2455580) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2B6 (RC217236). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2B6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2B6. 0.1 mL Log in to see Available
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 16 Days

Top referenced anti-CYP2B6 Antibodies

  1. Human Monoclonal CYP2B6 Primary Antibody for FACS, IF - ABIN2718982 : Sim, Nam, Lee, Lee, O, Joo, Liu, Han, Ki, Jeong, Lee, Lee: Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer. in Archives of pharmacal research 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CYP2B6 Primary Antibody for IF, IHC (p) - ABIN655056 : Bunten, Liang, Pounder, Seneviratne, Osselton: OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. in Clinical pharmacology and therapeutics 2010 (PubMed)
    Show all 3 Pubmed References

More Antibodies against CYP2B6 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) interaction partners

  1. Case Reports: CYP2B6-deficient alleles may be responsible for an increased conversion of ifosfamide into neurotoxic metabolites, leading to encephalopathy.

  2. The concentration-time curve (AUC(0(R)96)), maximum plasma concentration (Cmax), and terminal half-life (t1/2) values of Bupropion in CYP2B6*1/*4 were lower than those of CYP2B6*1/*1. The hydroxybupropion (HBUP) Cmax values in CYP2B6*4/*6 and CYP2B6*1/*4 increased by 1.12-fold and 1.97-fold, whereas the HBUP Cmax value in CYP2B6*1/*6 decreased to a value 1.64-fold lower than that in CYP2B6*1/*1

  3. CYP2B6-efavirenz analog complex provides a useful platform to investigate computationally as well as biophysically the effect of genetic polymorphisms on binding of the widely studied efavirenz.

  4. results indicate that the amino acid substitutions in the CYP2B6 variants suppressed the metabolic activation of CPS. CYP2B6 variants have altered capacity to bioactivate CPF (show NR5A2 Antibodies) and may affect individual susceptibility of CPF (show NR5A2 Antibodies)

  5. The findings of this study indicate that CYP2B6 contribute to the metabolism of MDMA to MDA in humans

  6. The first data of several CYP2B6 polymorphisms in Roma population.

  7. With consensus recommendations on downregulation, CYP2C (show CYP2C19 Antibodies) induction, and CYP2B6 positive control.

  8. Genotyping of CYP2B6 may therefore be of value when assessing dose requirements in methadone maintenance treatment.

  9. Genomic variation in CYP2B6 may explain, at least in part, severity of Neonatal Abstinence Syndrome

  10. CYP2B6 haplotype predicts efavirenz plasma concentration in black South African HIV-1-Infected children.

CYP2B6 Antigen Profile

Protein Summary

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene names and symbols associated with CYP2B6

  • cytochrome P450 family 2 subfamily B member 6 (CYP2B6) antibody
  • cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6) antibody
  • cytochrome P450 family 2 subfamily B member 6 L homeolog (cyp2b6.L) antibody
  • cytochrome P450 2B11 (CYP2B6) antibody
  • cytochrome P450 subfamily 2B (CYP2B6) antibody
  • cytochrome P450 2B11-like (LOC100068603) antibody
  • CPB6 antibody
  • CYP2B antibody
  • CYP2B6 antibody
  • CYP2B7 antibody
  • CYP2B7P antibody
  • CYP2B11 antibody
  • CYP2B30 antibody
  • CYPIIB6 antibody
  • CYPIIB11 antibody
  • EFVM antibody
  • IIB1 antibody
  • P450 antibody

Protein level used designations for CYP2B6

1,4-cineole 2-exo-monooxygenase , cytochrome P450 2B6 , cytochrome P450 IIB1 , cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 , cytochrome P450 CYP2B30 , cytochrome P450, family 2, subfamily B, polypeptide 6 , cytochrome P450 PBD-2 , cytochrome P450, family 2, subfamily B, polypeptide 11 , cytochrome P450 subfamily 2B , Cytochrome P450 2B6 , LOW QUALITY PROTEIN: cytochrome P450 2B11-like , cytochrome P450 2B11-like

1555 Homo sapiens
678687 Macaca mulatta
494798 Xenopus laevis
474177 Canis lupus familiaris
504769 Bos taurus
100068603 Equus caballus
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