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CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2B6 Kits (14) and CYP2B6 Proteins (3) and many more products for this protein.
Showing 10 out of 63 products:
Human Monoclonal CYP2B6 Primary Antibody for FACS, IF - ABIN2455580
Sim, Nam, Lee, Lee, O, Joo, Liu, Han, Ki, Jeong, Lee, Lee: Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer. in Archives of pharmacal research 2015
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Human Polyclonal CYP2B6 Primary Antibody for IF, IHC (p) - ABIN655056
Bunten, Liang, Pounder, Seneviratne, Osselton: OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. in Clinical pharmacology and therapeutics 2010
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G(516)T CYP2B6 polymorphisms was associated with Bronchopulmonary Dysplasia susceptibility in Preterm Neonates.
The deficient CYP2B6 516 T allele is associated with higher efavirenz plasma drug levels and more frequent central nervous system-related symptoms.
Males with the CYP2B6 *6/*6 genotype may be less susceptible to the development of anti-tuberculosis drug-induced hepatotoxicity.
CYP2B6 interindividual variability was not significantly associated with genetic variation in CYP2B6, nor was it associated with differences in gender or ethnicity, suggesting that factors other than these are largely responsible for the wide range of variability in CYP2B6 expression and activity observed among a large group of individuals/samples.
Established the regression models for CYP3A4 (show CYP3A4 Antibodies) and CYP2B6 inductions in human hepatocytes using azole compounds.
Phe206 plays a crucial role in determining the specificity of CYP2B6.
Homozygous carriers of CYP2B6*6 allele may be at increased risk for EFV-induced QT interval prolongation via inhibition of hERG (show KCNH2 Antibodies).
Genetic variations in CYP2B6 affect induction of Bupropion hydroxylation by sodium ferulate.
Genetic polymorphisms in CYP2B6 and CYP2A6 (show CYP2A6 Antibodies) explained a significant proportion of variability in EFV plasma concentration in HIV-infected children in a multi-ethnic outpatient clinic.
CYP2B6/CYP2A6 (show CYP2A6 Antibodies) genotypes were associated with increased reported suicidality among AIDS patients who had been randomly assigned to receive efavirenz-containing regimens in clinical trials. Strength of association varied by race/ethnicity.
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
cytochrome P450 2B6
, cytochrome P450 CYP2B30
, cytochrome P450, family 2, subfamily B, polypeptide 6
, cytochrome P450 PBD-2
, cytochrome P450, family 2, subfamily B, polypeptide 11
, cytochrome P450 2B3
, cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
, cytochrome P450IIB3
, 1,4-cineole 2-exo-monooxygenase
, cytochrome P450 IIB1