anti-Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) Antibodies

CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes.

list all antibodies Gene Name GeneID UniProt
Anti-Rat CYP2B6 CYP2B6 286953 P13107
Anti-Human CYP2B6 CYP2B6 1555 P20813
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Top anti-CYP2B6 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CYP2B6 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  THP-1 cell lysate Host:  Mouse  Target Name:  CYP2B10  Sample Tissue:  Mouse Pancreas  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-CYP2B6 mouse monoclonal antibody (ABIN2455580) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2B6 (RC217236). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2B6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2B6. 0.1 mL Log in to see Available
$482.90
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2B6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cytochrome P450 2B6 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytochrome P450 2B6 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of CYP2B6 Antibody (Center) (ABIN655056) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.4 mL Log in to see 8 to 11 Days
$517.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of P450R antibody in K562 cell line lysates (35ug/lane) P450R Antibody IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details

Top referenced anti-CYP2B6 Antibodies

  1. Human Monoclonal CYP2B6 Primary Antibody for FACS, IF - ABIN2718982 : Sim, Nam, Lee, Lee, O, Joo, Liu, Han, Ki, Jeong, Lee, Lee: Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer. in Archives of pharmacal research 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CYP2B6 Primary Antibody for IF, IHC (p) - ABIN655056 : Bunten, Liang, Pounder, Seneviratne, Osselton: OPRM1 and CYP2B6 gene variants as risk factors in methadone-related deaths. in Clinical pharmacology and therapeutics 2010 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CYP2B6 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) interaction partners

  1. The first data of several CYP2B6 polymorphisms in Roma population.

  2. With consensus recommendations on downregulation, CYP2C (show CYP2C19 Antibodies) induction, and CYP2B6 positive control.

  3. Genotyping of CYP2B6 may therefore be of value when assessing dose requirements in methadone maintenance treatment.

  4. Genomic variation in CYP2B6 may explain, at least in part, severity of Neonatal Abstinence Syndrome

  5. CYP2B6 haplotype predicts efavirenz plasma concentration in black South African HIV-1-Infected children.

  6. This is the first study that investigated the impact of the 516 G>T polymorphism of the CYP2B6 gene among HIV-positive individuals from southern Brazil. Its clinical significance indicates the need for prospective studies in this population.

  7. G(516)T CYP2B6 polymorphisms was associated with Bronchopulmonary Dysplasia susceptibility in Preterm Neonates.

  8. The deficient CYP2B6 516 T allele is associated with higher efavirenz plasma drug levels and more frequent central nervous system-related symptoms.

  9. Males with the CYP2B6 *6/*6 genotype may be less susceptible to the development of anti-tuberculosis drug-induced hepatotoxicity.

  10. CYP2B6 interindividual variability was not significantly associated with genetic variation in CYP2B6, nor was it associated with differences in gender or ethnicity, suggesting that factors other than these are largely responsible for the wide range of variability in CYP2B6 expression and activity observed among a large group of individuals/samples.

CYP2B6 Antigen Profile

Protein Summary

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene names and symbols associated with CYP2B6

  • cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6) antibody
  • cytochrome P450 family 2 subfamily B member 6 L homeolog (cyp2b6.L) antibody
  • cytochrome P450 2B11 (CYP2B6) antibody
  • cytochrome P450, family 2, subfamily b, polypeptide 3 (Cyp2b3) antibody
  • cytochrome P450 family 2 subfamily B member 6 (CYP2B6) antibody
  • CPB6 antibody
  • CYP2B antibody
  • Cyp2b6 antibody
  • CYP2B7 antibody
  • CYP2B7P antibody
  • CYP2B11 antibody
  • CYP2B30 antibody
  • CYPIIB6 antibody
  • CYPIIB11 antibody
  • EFVM antibody
  • IIB1 antibody
  • P450 antibody

Protein level used designations for CYP2B6

cytochrome P450 2B6 , cytochrome P450 CYP2B30 , cytochrome P450, family 2, subfamily B, polypeptide 6 , cytochrome P450 PBD-2 , cytochrome P450, family 2, subfamily B, polypeptide 11 , CYPIIB3 , cytochrome P450 2B3 , cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 , cytochrome P450IIB3 , 1,4-cineole 2-exo-monooxygenase , cytochrome P450 IIB1

GENE ID SPECIES
678687 Macaca mulatta
494798 Xenopus laevis
474177 Canis lupus familiaris
286953 Rattus norvegicus
1555 Homo sapiens
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