CYP2C8 Proteins
CYP2C8 encodes a member of the cytochrome P450 superfamily of enzymes.
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Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 1-490) protein (His tag) Protein
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) (AA 1-490) protein (GST tag) Protein
Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8) protein (Myc-DYKDDDDK Tag) Protein
CYP2C8 Protein Profile
Protein Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene names and symbols associated with CYP2C8
- cytochrome P450 family 2 subfamily C member 8 (CYP2C8) antibody
- Cytochrome P450 2C8 (CTN_0597) antibody
- cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8) antibody
- cytochrome P450 family 2 subfamily C member 8 S homeolog (cyp2c8.1.S) antibody
- cytochrome P450 family 2 subfamily C member 8 (cyp2c8.1) antibody
- cpc8 antibody
- cyp2c8 antibody
- CYP2C74 antibody
- cypiic8 antibody
- mp-12/mp-20 antibody
Protein level used designations for CYP2C8
P450 form 1 , cytochrome P450 2C8 , cytochrome P450 IIC2 , cytochrome P450 MP-12 , cytochrome P450 MP-20 , cytochrome P450 form 1 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8 , flavoprotein-linked monooxygenase , microsomal monooxygenase , s-mephenytoin 4-hydroxylase , xenobiotic monooxygenase , Cytochrome P450 2C8 , cytochrome P450 CYP2C74 , cytochrome P450, family 2, subfamily C, polypeptide 8
GENE ID | SPECIES |
---|---|
1558 | Homo sapiens |
7378980 | Thermotoga neapolitana DSM 4359 |
678683 | Macaca mulatta |
379297 | Xenopus laevis |
450909 | Pan troglodytes |
100127852 | Xenopus (Silurana) tropicalis |
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- Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 Proteins
- Cytochrome P450, Family 2, Subfamily C, Polypeptide 18 Proteins
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