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May be involved in the metabolism of various pneumotoxicants including naphthalene. Additionally we are shipping Cytochrome P450, Family 2, Subfamily F, Polypeptide 1 Antibodies (21) and many more products for this protein.
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Tissue distribution of transgenic mRNA expression agrees well with the known respiratory tract-selective expression of CYP2A13 (show CYP2A13 Proteins) and CYP2F1 and hepatic expression of CYP2B6 (show CYP2B6 Proteins) in humans.
Patients with occupational chronic bronchitis and healthy workers significantly differed from each other in the frequency distribution of the genotypes ofthe CYP2F1 (rs11399890, c.14_15insC
Association analysis of CYP2F1 gene insertion variant with chronic obstructive pulmonary disease have shown high frequency (87.5%) of normal allele in Tatars patients with very severe stage and manifestation of chronic obstructive pulmonary disease.
a novel LSF (show TFCP2 Proteins)(lung-specific factor) and its consensus sequence that may control tissue-specific expression of CYP2F1.
A lot of genetic polymorphism of CYP2F1 gene is found in Guangdong population of China, however, no single genetic polymorphism associated with the individual susceptibility to nasopharyngeal carcinoma can be identified.
24 novel mutations distributed in the promoter region of the gene, as well as in the coding regions and their flanking intronic sequences;the CYP2F1 genetic polymorphism has no implications in the pathogenesis of lung cancer
May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine.
, cytochrome P450 2F1
, cytochrome P450, subfamily IIF, polypeptide 1
, flavoprotein-linked monooxygenase
, microsomal monooxygenase
, xenobiotic monooxygenase
, cytochrome P450, family 2, subfamily F, polypeptide 1
, novel cytochrome P450 cyp2 family protein