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CYP2W1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 Antibodies (62) and many more products for this protein.
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showed that the genetic pattern of CYP2W1 is interethnically different among the three Chinese populations, and this finding can extend our understanding of population genetics of CYP2W1 in the Chinese population
summarizes the history, distribution, polymorphism, membrane topology, function and possible role in cancer therapy of CYP2W1.
Normal adrenal tissue lacks CYP2W1 enzyme expression; adrenocortical carcinomas generally do not express the enzyme as well.
Report novel SNPs of CYP2W1 gene in Chinese Uygur and Han populations.
Data suggest that canonical cytochrome P-450 reductants (cytochrome P450 reductase (show POR Proteins); cytochrome b5 (show CYB5A Proteins)) cannot serve as electron donors for CYP2W1, a colon tumor-specific enzyme; glycosylation of CYP2W1 at Asn177 is required for full catalytic activity.
Results show the developmental expression of CYP2W1 in the GI tract mediated by epigenetic modifications, its specific location, and regulation by anticancer drugs which can be considered as an adjuvant therapy of colon and hepatic cancers.
Low KRT13 (show KRT13 Proteins) mRNA expression is associated with oral squamous cell carcinoma.
CYP2W1 is highly expressed in both normal and neoplastic adrenal glands making it a promising tool for targeted therapy in ACC
High CYP2W1 expression is seen in 26% of primary colorectal tumors and in 48% of corresponding liver metastases.
CYP2W1 could play an important role in hepatocellular carcinoma (HCC (show FAM126A Proteins)) and might serve as a valuable prognostic marker and potential target for gene therapy in the treatment of HCC (show FAM126A Proteins).
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
cytochrome P450, family 2, subfamily W, polypeptide 1
, cytochrome P450 2W1