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CYP4Z1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP4Z1 Antibodies (42) and many more products for this protein.
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This study reports on the creation of a new homology model of CYP4Z1 and performed molecular docking experiments, which indicate that all active substrates show a highly similar binding geometry compared to the endogenous substrates.
CYP4Z1 3'UTR could inhibit the migration and Epithelial-mesenchymal transition of breast cancer cells.
Data show that downregulation of cytochrome P450 family 4 CYP4Z1 or the pseudogene CYP4Z2P 3'-UTR promotes cell apoptosis.
CYP4Z1 and CYP4Z2P were downregulated in MCF-7 cells compared with tamoxifen-resistant MCF-7-TamR cells
Our findings suggest that the CYP4Z2P- and CYP4Z1-3'UTR promote breast cancer angiogenesis collectively by activating the PI3K and ERK1/2 pathways through binding multiple miRNAs.
CYP4Z1 overexpression promotes tumor angiogenesis and growth in breast cancer partly via PI3K/Akt and ERK1/2 activation
CYP4Z1, KIR (show GEM Proteins) and RDH10 (show RDH10 Proteins) could play a role in non-small-cell lung cancer progression
Human cytochrome P450 (CYP), termed CYP4Z1,was identified, and the cDNA was cloned from a breast carcinoma line .
PPARalpha (show PPARA Proteins) has a role in CYP4X1 (show CYP4X1 Proteins) regulation, and the glucocorticoid and progesterone receptors have roles in CYP4Z1 gene activation
CYP4Z1-dependent in-chain hydroxylation of lauric and myristic acid, which in both cases leads to the formation of four different monohydroxylated products at positions omega-2, omega-3, omega-4, and omega-5, respectively
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 1p33.
, cytochrome P450 4Z1