Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 Proteins

CYP46A1 encodes a member of the cytochrome P450 superfamily of enzymes.

Data Quality
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Type
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    Protein
Antigen
  • 4
Reactivity
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  • 1
Application
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  • 2
  • 2
  • 1
Host
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  • 1
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Binding Specificity
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Conjugate
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Protein Type
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Format
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4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityMouse (Murine)
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3120164
$5,122.60
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3078091
$7,294.44
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 50 to 55 Business Days
ReactivityHuman
Application AA, AP, ELISA, WB
Order details Cat. No. ABIN1351000
$414.29
Plus shipping costs $45.00 and $22.00 dry ice
Delivery in 11 to 12 Business Days
Recombinant Protein, HEK-293 Cells (Source), Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivityHuman
Application AbP, Func, PI, STD
Order details Cat. No. ABIN2712777
$888.80
20 μg
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 11 Business Days
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Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Gene names and symbols associated with CYP46A1

  • cytochrome P450 family 46 subfamily A member 1 (CYP46A1) antibody
  • cytochrome P450 family 46 subfamily A member 1 L homeolog (cyp46a1.L) antibody
  • cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 (cyp46a1.1) antibody
  • cytochrome P450, family 46 (cyp46a1) antibody
  • cytochrome P450 46A1 (PTRG_08343) antibody
  • cytochrome P450 46A1 (PTRG_09667) antibody
  • cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1) antibody
  • cholesterol 24-hydroxylase (Sgly_1093) antibody
  • cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1) antibody
  • CP46 antibody
  • Cyp46 antibody
  • CYP46A1 antibody
  • MGC147389 antibody
  • zgc:109896 antibody

Protein level used designations for CYP46A1

CH24H , cholesterol 24-hydroxylase , cytochrome P450 46A1 , cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase) , cytochrome P450, family 46, subfamily A, polypeptide 1 , cytochrome P450, family 46 , cholestrol 24-hydroxylase , cytochrome P450, 46 (cholesterol 24-hydroxylase) , cytochrome P450, 46a1 (cholesterol 24-hydroxylase) , cholesterol-24S-hydroxylase

GENE ID SPECIES
10858 Homo sapiens
379470 Xenopus laevis
423450 Gallus gallus
453154 Pan troglodytes
553543 Danio rerio
780005 Xenopus (Silurana) tropicalis
6346625 Pyrenophora tritici-repentis Pt-1C-BFP
6347960 Pyrenophora tritici-repentis Pt-1C-BFP
13116 Mus musculus
362782 Rattus norvegicus
10248273 Syntrophobotulus glycolicus DSM 8271
506438 Bos taurus
480432 Canis lupus familiaris