anti-DEK Oncogene (DEK) Antibodies

DEK encodes a protein with one SAP domain. Additionally we are shipping DEK Kits (7) and DEK Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DEK 7913 P35659
DEK 306817 Q6AXS3
DEK 110052 Q7TNV0
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-DEK Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DEK Antibody Titration:  1.25ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DEK Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB DEK Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of DEK Antibody (C-term) (Cat#AP51234PU-N) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of DEK Antibody (C-term) (ABIN653133) in WiDr cell line lysates (35 µg/lane). DEK (arrow) was detected using the purified polyclonal antibody. DEK Antibody (C-term) (ABIN653133) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$385.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, WB ABIN6272941 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of HeLa cells, using DEK antibody. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IHC Immunohistochemistry: DEK Antibody [NBP2-49135] - Staining of human stomach shows moderate nuclear positivity in glandular cells. Immunohistochemistry-Paraffin: DEK Antibody  - Staining of human pancreas shows low expression as expected. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC, WB Western Blot and Immunoprecipitation: DEK Antibody [ABIN253197] - Detection of Human DEK by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-DEK antibody ABIN253197 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B). DEK was immunoprecipitated by another rabbit anti-DEK antibodies and ABIN253196, which recognize upstream epitopes. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 Immunohistochemistry-Paraffin: DEK Antibody [ABIN2531978] - Human stomach carcinoma. Antibody used at a dilution of 1:200 (1ug/ml). 0.1 mL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IP, IHC Western Blot: DEK Antibody [ABIN253196] - Detection of Human DEK by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-DEK antibody ABIN253196 used for IP at 3 mcg/mg lysate. DEK was also immunoprecipitated by another rabbit anti-DEK antibody, which recognizes an upstream epitope.  Detection: Chemiluminescence with an exposure time of 3 Immunohistochemistry-Paraffin: DEK Antibody [ABIN2531967] - Human prostate carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of PC3 cell lines, using DEK antibody. Western blot analysis of extracts of various cell lines, using DEK antibody (ABIN4903467) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s. 100 μL Log in to see 11 to 13 Days
$366.77
Details

Top referenced anti-DEK Antibodies

  1. Human Polyclonal DEK Primary Antibody for IF (p), IHC (p) - ABIN729268 : Yang, Wu, Geng, Liu, Yang, Chen, Ding, He, Wang, Xie: Roles of DEK in the endometrium of mice in early pregnancy. in Gene 2017 (PubMed)

  2. Human Polyclonal DEK Primary Antibody for IF, IHC - ABIN1085125 : Matrka, Cimperman, Haas, Guasch, Ehrman, Waclaw, Komurov, Lane, Wikenheiser-Brokamp, Wells: Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. in PLoS genetics 2018 (PubMed)

  3. Human Polyclonal DEK Primary Antibody for IHC (p), IP - ABIN253197 : Datta, Adelson, Mogilevkin, Mordechai, Sidi, Trama: Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer. in BMC cancer 2011 (PubMed)

  4. Cow (Bovine) Polyclonal DEK Primary Antibody for WB - ABIN2792543 : Orlic, Spencer, Wang, Gallie: Expression analysis of 6p22 genomic gain in retinoblastoma. in Genes, chromosomes & cancer 2005 (PubMed)
    Show all 2 Pubmed References

  5. Cow (Bovine) Polyclonal DEK Primary Antibody for WB - ABIN2792529 : Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 Pubmed References

More Antibodies against DEK Interaction Partners

Human DEK Oncogene (DEK) interaction partners

  1. DEK is overexpressed in HGSOCs, and decreasing DEK levels significantly reduces cell viability and tumor growth, resulting in apoptotic cell death.

  2. These findings define DEK as an important and multifunctional mediator of homologous recombination.

  3. DEK is detected in spontaneously forming neutrophil extracellular traps (NETs) from juvenile idiopathic arthritis patient synovial neutrophils, and DEK-targeted aptamers reduce NETs formation.

  4. High DEK proto-oncogene protein (DEK) expression associated with complete response to neoadjuvant chemoradiotherapy.

  5. High DEK expression is associated with cervical cancer tumorigenesis and metastasis.

  6. The results of the present study demonstrated that EMT of colorectal carcinoma cells was partially mediated by DEK, which likely affected the invasive ability of colorectal carcinoma cells. In addition, cell proliferation and apoptosis were susceptible to DEK silencing.

  7. RNA-sequencing proved to be a valuable tool for the detection of a fusion of genes DEK and NUP214 in a leukemia that showed cryptic cytogenetic rearrangement of chromosome band 9q34.

  8. DEK overexpression enhanced carcinogenesis, including field cancerization, in OSCC by stimulating the G1 /S phase transition and promoting DNA replication.

  9. DEK and LCMR1 were demonstrated to cooperate in the inhibition of apoptosis in lung cancer cells.

  10. High DEK expression is associated with breast cancer angiogenesis .

  11. our study indicates that DEK expression is required for tumorigenesis and metastasis of hepatocellular carcinoma

  12. High DEK expression is associated with melanoma progression.

  13. DEK correlates with IL6 expression in HPV16+/p16+ oropharyngeal squamous cell carcinomas (OPSCC).

  14. data support a scenario whereby overexpression of the human DEK oncogene reprograms keratinocyte metabolism to fulfill energy and macromolecule demands required to enable and sustain cancer cell growth

  15. Decreased DEK expression in plasma cells suggests a potential role of this gene in plasma cell development and lack of detectable DEK protein by IHC could be used as a biomarker for normal and malignant plasma cells

  16. Our data indicated DEK plays multiple roles to facilitate tumor growth and maintenance. It can be used as a potential target for astrocytic tumor diagnosis and gene therapy.

  17. High DEK expression is associated with pancreatic ductal adenocarcinoma.

  18. AP-2a is an important transcription factor of DEK expression, which is correlated with the methylation level of the DEK core promoter in hepatocellular carcinoma .

  19. miR-592 targets DEK transcript and suppresses hepatocellular carcinoma cell growth

  20. Results find that DEK binds to transcription start sites with a dual role in activation and repression of highly and ubiquitously expressed genes.

Mouse (Murine) DEK Oncogene (DEK) interaction partners

  1. These findings define DEK as an important and multifunctional mediator of homologous recombination.

  2. DEK is crucial to the development of arthritis in mouse models, thus making it an appropriate target for aptamer-based therapy.

  3. DEK was expressed throughout the brain in both sexes, including the medial prefrontal cortex (prelimbic, infralimbic and dorsal peduncular). DEK was also abundant in all amygdalar subdivisions (basolateral, central and medial) and in the hippocampus including the CA1, CA2, CA3, dentate gyrus (DG), ventral subiculum and entorhinal cortex.

  4. Dek contributes to esophageal squamous cell carcinoma tumorigenesis at least partially through keratinocyte intrinsic pathways which promote cellular and tumor growth.

  5. Data suggests that DEK participates in the process of embryo implantation and might play a role in influencing stromal cell decidualization through mediating cell proliferation, apoptosis and DNA damage.

  6. DEK expression during normal hematopoiesis did reveal a relationship with specific cell types implicating a distinct function during myeloid differentiation

  7. Studies demonstrate that DEK overexpression, due in part to Ron receptor activation, drives breast cancer progression through the induction of Wnt/beta-catenin signaling.

  8. Results highlight a novel function of DEK as a guardian of chromatin by restricting widespread histone access, and in particular by modulating differential H3.3 loading in specific chromatin areas.

  9. data demonstrate that DEK stimulates HNSCC cellular growth and identify DeltaNp63 as a novel DEK effector

  10. DEK has potent effects on HSCs, HPCs, and hematopoiesis, information of biological and potential clinical interest.

  11. The hallmark of translocation in acutte myeloid leukemiaa is the expression of the DEK/CAN fusion protein.

  12. DEK is a neuroblastoma tumor antigen.

  13. Our conclusion is that DEK could serve as an architectural protein at the promoter or enhancer sites of a subfraction of human genes.

  14. Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo.

DEK Antigen Profile

Protein Summary

This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-DEK Oncogene (DEK) Antibodies

  • DEK proto-oncogene (DEK) antibody
  • DEK proto-oncogene (Dek) antibody
  • DEK proto-oncogene L homeolog (dek.L) antibody
  • DEK oncogene (DNA binding) (Dek) antibody
  • DEK oncogene (LOC398543) antibody
  • 1810019E15Rik antibody
  • D6S231E antibody
  • D13H6S231E antibody
  • DEK antibody

Protein level used designations for anti-DEK Oncogene (DEK) Antibodies

DEK oncogene (DNA binding) , protein DEK , DEK oncogene

GENE ID SPECIES
7913 Homo sapiens
306817 Rattus norvegicus
462460 Pan troglodytes
540945 Bos taurus
610538 Canis lupus familiaris
100340537 Oryctolagus cuniculus
100380963 Xenopus laevis
110052 Mus musculus
420828 Gallus gallus
101090769 Felis catus
100731281 Cavia porcellus
100156871 Sus scrofa
Selected quality suppliers for anti-DEK (DEK) Antibodies
Did you look for something else?