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DEK encodes a protein with one SAP domain. Additionally we are shipping DEK Kits (7) and DEK Proteins (4) and many more products for this protein.
Showing 10 out of 63 products:
Human Polyclonal DEK Primary Antibody for IF (p), IHC (p) - ABIN729268
Yang, Wu, Geng, Liu, Yang, Chen, Ding, He, Wang, Xie: Roles of DEK in the endometrium of mice in early pregnancy. in Gene 2017
Cow (Bovine) Polyclonal DEK Primary Antibody for WB - ABIN2792529
Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer. in Biochemical and biophysical research communications 2008
Show all 2 Pubmed References
Cow (Bovine) Polyclonal DEK Primary Antibody for WB - ABIN2792543
Orlic, Spencer, Wang, Gallie: Expression analysis of 6p22 genomic gain in retinoblastoma. in Genes, chromosomes & cancer 2005
Show all 2 Pubmed References
Human Polyclonal DEK Primary Antibody for IHC (p), IP - ABIN253197
Datta, Adelson, Mogilevkin, Mordechai, Sidi, Trama: Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer. in BMC cancer 2011
Human Polyclonal DEK Primary Antibody for IF, IHC - ABIN1085125
Matrka, Cimperman, Haas, Guasch, Ehrman, Waclaw, Komurov, Lane, Wikenheiser-Brokamp, Wells: Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. in PLoS genetics 2018
These findings define DEK as an important and multifunctional mediator of homologous recombination.
DEK is detected in spontaneously forming neutrophil extracellular traps (NETs) from juvenile idiopathic arthritis patient synovial neutrophils, and DEK-targeted aptamers reduce NETs formation.
High DEK proto-oncogene (show RAB1A Antibodies) protein (DEK) expression associated with complete response to neoadjuvant chemoradiotherapy.
High DEK expression is associated with cervical cancer tumorigenesis and metastasis.
The results of the present study demonstrated that EMT (show ITK Antibodies) of colorectal carcinoma cells was partially mediated by DEK, which likely affected the invasive ability of colorectal carcinoma cells. In addition, cell proliferation and apoptosis were susceptible to DEK silencing.
RNA-sequencing proved to be a valuable tool for the detection of a fusion of genes DEK and NUP214 (show NUP214 Antibodies) in a leukemia that showed cryptic cytogenetic rearrangement of chromosome band 9q34.
DEK overexpression enhanced carcinogenesis, including field cancerization, in OSCC by stimulating the G1 /S phase transition and promoting DNA replication.
DEK and LCMR1 (show MED19 Antibodies) were demonstrated to cooperate in the inhibition of apoptosis in lung cancer cells.
High DEK expression is associated with breast cancer angiogenesis .
our study indicates that DEK expression is required for tumorigenesis and metastasis of hepatocellular carcinoma
DEK is crucial to the development of arthritis in mouse models, thus making it an appropriate target for aptamer-based therapy.
DEK was expressed throughout the brain in both sexes, including the medial prefrontal cortex (prelimbic, infralimbic and dorsal peduncular). DEK was also abundant in all amygdalar subdivisions (basolateral, central and medial) and in the hippocampus including the CA1 (show CA1 Antibodies), CA2 (show CA2 Antibodies), CA3 (show CA3 Antibodies), dentate gyrus (DG), ventral subiculum and entorhinal cortex.
Dek contributes to esophageal squamous cell carcinoma tumorigenesis at least partially through keratinocyte intrinsic pathways which promote cellular and tumor growth.
Data suggests that DEK participates in the process of embryo implantation and might play a role in influencing stromal cell decidualization through mediating cell proliferation, apoptosis and DNA damage.
DEK expression during normal hematopoiesis did reveal a relationship with specific cell types implicating a distinct function during myeloid differentiation
Studies demonstrate that DEK overexpression, due in part to Ron (show MST1R Antibodies) receptor activation, drives breast cancer progression through the induction of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.
Results highlight a novel function of DEK as a guardian of chromatin by restricting widespread histone access, and in particular by modulating differential H3.3 loading in specific chromatin areas.
data demonstrate that DEK stimulates HNSCC cellular growth and identify DeltaNp63 as a novel DEK effector
DEK has potent effects on HSCs, HPCs, and hematopoiesis, information of biological and potential clinical interest.
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
DEK oncogene (DNA binding)
, protein DEK
, DEK oncogene