DEK antibody (Middle Region)

Catalog No. ABIN2792529

Cited in 1 publication. The Rabbit Polyclonal anti-DEK antibody (ABIN2792529) specifically detects DEK in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse and Pig samples.

Quick Overview for DEK antibody (Middle Region) (ABIN2792529)

Target: DEK (DEK Oncogene (DEK))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DEK Antibody

Binding Specificity: Middle Region

Purpose: DEK Antibody - middle region

Sequence: ELKETIKKLL ASANLEEVTM KQICKKVYEN YPTYDLTERK DFIKTTVKEL

Cross-Reactivity: Cow (Bovine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DEK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DEK antibody (ABIN2792529)

Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

Target Details for DEK

Target: DEK (DEK Oncogene (DEK))

Alternative Name: DEK

Background:

Background Information: DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: DEK oncogene

Alternative Symbols: D6S231E

Protein Name: Protein DEK

Molecular Weight: 43kDa

Gene ID: 7913

NCBI Accession: NP_003463

UniProt: P35659