anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antibodies

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Additionally we are shipping DNA (Cytosine-5)-Methyltransferase 1 Kits (20) and DNA (Cytosine-5)-Methyltransferase 1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top anti-DNA (Cytosine-5)-Methyltransferase 1 Antibodies at antibodies-online.com

Showing 10 out of 547 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Mouse Rabbit Un-conjugated WB Researcher: AnonymousApplication: Western BlottingSpecies+tissue/cell type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 WB Suggested Anti-Dnmt1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Mouse Lung 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN308397 (0.5µg/ml) staining of Jurkat cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Fish Mouse Un-conjugated ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg 3 to 4 Days
$453.70
Details
Fish Mouse Un-conjugated ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg 3 to 4 Days
$453.70
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Human Rabbit Un-conjugated EIA, WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-Dnmt1 Polyclonal Antibody, Unconjugated (ABIN671796) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Dnmt1 Polyclonal Antibody, Unconjugated (ABIN671796) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$329.45
Details
Human Mouse FITC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DNMT1 Monoclonal Antibody, Clone 11H8 . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-DNMT1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Nucleus. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) DNMT1. (D) Composite. 100 μg 3 to 4 Days
$492.70
Details
Human Mouse PerCP ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DNMT1 Monoclonal Antibody, Clone 11H8 . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-DNMT1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Nucleus. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) DNMT1. (D) Composite. 100 μg 3 to 4 Days
$501.80
Details
Human Mouse APC ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DNMT1 Monoclonal Antibody, Clone 11H8 . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-DNMT1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Nucleus. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) DNMT1. (D) Composite. 100 μg 3 to 4 Days
$501.80
Details
Human Mouse Atto 565 ICC, IF, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-DNMT1 Monoclonal Antibody, Clone 11H8 . Tissue: Colon carcinoma cell line (RKO). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-DNMT1 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60 min at RT, 5 min at RT. Localization: Nucleus. Magnification: 60X. (A) DAPI nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) DNMT1. (D) Composite. 100 μg 3 to 4 Days
$503.10
Details

Top referenced anti-DNA (Cytosine-5)-Methyltransferase 1 Antibodies

  1. Human Monoclonal DNMT1 Primary Antibody for ChIP, CyTOF - ABIN252481 : Dennis, Fan, Geiman, Yan, Muegge: Lsh, a member of the SNF2 family, is required for genome-wide methylation. in Genes & development 2001 (PubMed)
    Show all 112 Pubmed References

  2. Human Monoclonal DNMT1 Primary Antibody for ChIP, IHC (p) - ABIN531980 : Du, Zhou, Liu, Jiang, Wang, Hu, Qi, Zhong, Wang, Li: Arsenic induces functional re-expression of estrogen receptor ? by demethylation of DNA in estrogen receptor-negative human breast cancer. in PLoS ONE 2012 (PubMed)
    Show all 11 Pubmed References

  3. Polyclonal DNMT1 Primary Antibody for IP, WB - ABIN540875 : Robert, Morin, Beaulieu, Gauthier, Chute, Barsalou, MacLeod: DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. in Nature genetics 2003 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal DNMT1 Primary Antibody for ChIP, IP - ABIN2668504 : Schnekenburger, Talaska, Puga: Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. in Molecular and cellular biology 2007 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal DNMT1 Primary Antibody for WB - ABIN6679357 : Xie, Zhang, Wang, Zhao, Zhang, Yao, Hur, Yeh, Pang, Zheng, Fan, Kong, Wang, Chiu, Zhou: Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1. in Biomaterials 2018 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal DNMT1 Primary Antibody for DB, ELISA - ABIN4369817 : Saito, Kanai, Nakagawa, Sakamoto, Saito, Ishii, Hirohashi: Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal DNMT1 Primary Antibody for DB, ELISA - ABIN545846 : Leng, Stidley, Bernauer, Picchi, Sheng, Frasco, Van Den Berg, Gilliland, Crowell, Belinsky: Haplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokers. in Carcinogenesis 2008 (PubMed)
    Show all 3 Pubmed References

  8. Human Polyclonal DNMT1 Primary Antibody for WB - ABIN6139745 : Wang, Li, Zhu, Lin, Luo, Zhao, Zhang, Li, Gao, Liang, Liu, Tsun, Yuan, Wu, Li: DNMT1 cooperates with MBD4 to inhibit the expression of Glucocorticoid-induced TNFR-related protein in human T cells. in FEBS letters 2017 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal DNMT1 Primary Antibody for FACS, ICC - ABIN6670861 : Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model. in Clinical epigenetics 2016 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal DNMT1 Primary Antibody for IHC (p), IHC - ABIN314281 : Nanduri, Makarenko, Reddy, Yuan, Pawar, Wang, Khan, Zhang, Kinsman, Peng, Kumar, Fox, Godley, Semenza, Prabhakar: Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 2 Pubmed References

More Antibodies against DNA (Cytosine-5)-Methyltransferase 1 Interaction Partners

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. DNMT1 as a potential new small ubiquitin-related modifier-targeted ubiquitin E3 ligase substrate of RNF4, with knockdown of dnmt1 largely restoring primitive and definitive granulopoiesis in rnf4-deficient zebrafish

  2. Dnmt1 stability requires UHRF1 phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  3. Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  4. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa regulation during definitive hematopoiesis in zebrafish

  5. These data provide the first evidence that Uhrf1 and Dnmt1 function is required for vertebrate lens development and maintenance.

  6. Spatial and temporal regulation of this gene suggests specific functions for the enzyme during oogenesis and early development of zebrafish.

  7. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 and that, together, Dnmt1 and Suv39h1 help guide the terminal differentiation of particular tissues.

  8. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  9. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. DNMT1 polymorphism rs2228611 AA genotype was a risk factor for idiopathic sudden sensorineural hearing loss (ISSHL) patients and rs2228612 GG genotype could be a protective factor in Turkish population.

  2. The chemotherapeutic effect might be due to the epigenetic modification particularly DNA hypomethylation through downregulation of DNMT1.

  3. Loss of PPARalpha from the intestine promotes colon carcinogenesis by increasing DNMT1/PRMT6-mediated DNA methylation.

  4. In vitro experiments confirmed that UVA irradiation reduced p53 promoter methylation, and DNMT1 up-regulation could reverse this effect.

  5. BACE1 expression in retinal epithelium pigment cells is competitively regulated by Sp1 and DNMT1 after photo-oxidation.

  6. The methylation level is reduced in the villi of women with unexplained recurrent spontaneous abortion, which may be correlated with up-regulated expression of DNMT1 and DNMT3b and down-regulated expression of TET1 and TET2.

  7. these results demonstrated that DNMT1 depletion caused hypomethylation and upregulation of MyD88, which resulted in activation of the NF-kappaB pathway and the subsequent release of lipoteichoic acid -induced inflammatory cytokines in human odontoblast-like cells.

  8. SRSF1 expression levels were significantly lower in T cells from systemic lupus erythematosus (SLE) patients compared to healthy subjects, and correlated inversely with disease activity and positively with levels of RasGRP1-WT and DNMT1. AS to RasGRP1-WT and decreased levels of RasGRP1 protein, whereas overexpression of SRSF1 in SLE T-cells caused recovery of RasGRP1, which in turn induced DNMT1/interleukin-2 expression.

  9. DNMT1 was identified to be a downstream target of miR148a, and was negatively regulated by miR148a in AML cell lines, suggesting that miR148a and DNMT1 form a mutual negative feedback loop.

  10. Study identifies rare DNMT1 missense variants in individuals affected with Beckwith-Wiedemann syndrome (BWS). The data suggests that reduced DNMT1 activity could affect maintenance of methylation at KCNQ1OT1 TSS-DMR in some cases of BWS, possibly via a maternal effect in the early embryo.

  11. Molecular dynamics simulations revealed that DNMT1 forms an unproductive complex with DNA duplexes containing oxidized forms of mC as a consequence of altered interactions of the target recognition domain of the protein with the C-5 substituent on cytosine.

  12. in hISMC from resected Crohn's strictures, we observed a significantly reduced contractile phenotype compared with patient-matched intrinsic controls that was associated with increased patient-specific expression of DNA methyltransferase 1, HDAC2, and HDAC5.

  13. Latent autoimmune diabetes of adults (LADA) patients showed stronger binding of p-STAT3, HDAC5 and DNMT1 than controls.

  14. Results show that DNMT1 converts hemimethylated DNA to fully methylated DNA during DNA replication and binds to SAHH.

  15. The expression of Kindlin-2 positively correlated with DNA methyltransferase 1(DNMT1) in breast cancer patients. Mechanistically, Kindlin-2 increased the stability of DNA methyltransferase DNMT1 through interaction with DNMT1 and methylated CpG islands in the E-cadherin promoter.

  16. The authors demonstrated a significantly increased risk of idiopathic infertility with abnormal semen parameters in association with the heterozygous genotype of variant rs4804490. Moreover, the AA genotype of variant rs4804490 was associated with significantly decreased risk for male infertility with abnormal semen parameters.

  17. The active nucleotide of RX-3117 is incorporated into DNA leading to downregulation of DNMT1, the maintenance DNA methylation enzyme.

  18. in metastatic breast cancer, tumoral DNMT1 expression was low in bone metastasis and highest in brain metastasis

  19. DNMT1 upregulation could partially rescue the properties of CD133+/CD44+ shOPN cells. Both in vitro and in vivo assays showed that CD133+/CD44+ cells with high OPN levels were more sensitive to DNA methylation inhibitor, 5 Azacytidine (5 Aza).

  20. CRISPR-Cas9-targeted DNMT1 manipulation may be a potential therapeutic regimen for ovarian cancer, and lipid-mediated delivery systems represent promising delivery vectors of CRISPR-Cas9 technology for precise genome editing therapeutics.

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a, Hdac1, Kdm3a and Uhrf1 were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. DNMT1 silencing significantly decreased the methylation levels of miR-29b promoter, up-regulated miR-29b expression and inhibited bovine viral diarrhea virus replication.

  2. Through down-regulating the expression of DNMT1, miR-152 reduced Global DNA methylation and the activity of DNMT to reactivate the lactation signal transduction genes Akt and Ppar gamma.

  3. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 mRNA was present at highest levels in transgenic SCNT embryos.

  4. Our results indicate an essential role for Dnmt1 during bovine preimplantation development, and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  5. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  6. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  7. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. The findings reveal that MET1-mediated shoot regeneration is regulated by the cytokinin-induced cell cycle, and provide new insights into the regulation of DNA methylation in shoot regeneration.

  2. Long-term stability and epigenetic features differ for individual loci. Our data show that over-expression of MET1, and potentially of other genes encoding epigenetic factors, offers an alternative strategy to identify epigenetic target genes and to create novel epi-alleles

  3. MET1 confines ARID1 to the vegetative cell of male gametes, but ARID1 conversely represses MET1 in the central cell of female gametes.

  4. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  5. Met1 gene expression throughout normal development, particularly in the flower

  6. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  7. VIM proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation and histone modification status in collaboration with MET1

  8. VIM proteins function in transcriptional regulation via their roles in the MET1 DNA methylation pathway.

  9. Genetic studies indicate that the Polycomb Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  10. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

  11. There is a mechanistic link between two major epigenetic pathways involved in histone and DNA methylation in plants by physical interaction of MET1 with the FIS-PRC2 core component MEA.

  12. Our results bear interesting similarities with cancer cells, which show global losses of DNA methylation but ectopic hypermethylation of genes previously marked by H3K27m3.

  13. An intergenic nucleosome-free crossover hotspot 3a undergoes increased recombination activity in met1.

  14. HDA6 and MET1 interact directly and act together to silence transposable elements by modulating DNA methylation, histone acetylation, and histone methylation status.

  15. functional loss of key epigenetic genes-including METHYLTRANSFERASE1 (MET1) encoding for DNA methyltransferase, in Arabidopsis

  16. The methylation patterns of the MET1 gene in organs of Arabidopsis thaliana were studied.

  17. Maternal and paternal genomes play distinct roles in the regulation of seed size in Arabidopsis, as determined by mutation status of DDM1 and MET1.

  18. control DNA methylation in Arabidopsis thaliana.[review]

  19. Three methyltransferases MET1, CMT3 and DRM1/2 are all required cooperatively for RPS methylation both at CG and non-CG sites.

  20. Continuous MET1 activity in dividing cells is essential for proper patterns of CG DNA methylation & development.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) interaction partners

  1. Loss of PPARalpha from the intestine promotes colon carcinogenesis by increasing DNMT1/PRMT6-mediated DNA methylation.

  2. these results highlight the role of DNMT1 in regulating epithelial bud formation by maintaining cell cycle progression and survival of rapidly dividing urethral epithelial cells, which can be extended to the study of other developing epithelial organs.

  3. Data indicate the regulatory mechanism of DNA methyltransferase (cytosine-5) 1 (DNMT1) activation by UHRF1 and supports that individual domains of ubiquitin-like-containing PHD and RING finger domains protein 1 (UHRF1) participate and act in concert to maintain DNA methylation patterns.

  4. Stella safeguards the unique oocyte epigenome by preventing aberrant de novo DNA methylation mediated by DNMT1 and UHRF1

  5. Upregulation of Dnmt1 as a consequence of BCR-ABLp210 DNA induces methylation changes and thus myeloid malignancies.

  6. DNMT1 responds to multiple regulatory inputs that control its localization as well as its activity

  7. DNA methyltransferases 1 (DNMT1) inhibits high-mobility group box 1(HMGB1) expression in hypoxia-induced apoptosis in cardiac progenitor cells (CPCs).

  8. DNMT1 regulates Pak6 transcription through crosstalk with histone modifications in developing interneurons.

  9. we found that the effect of genipin on PRS mice occurs through DNA demethylation by inhibiting DNA methyltransferase 1 (DNMT1), normalizing the expression of reduced brain-derived neurotrophic factor (BDNF) in the hippocampus

  10. L3MBTL3 binds the K142-methylated DNMT1 and recruits a novel CRL4(DCAF5) ubiquitin ligase to degrade DNMT1.

  11. MiR-139-5p reduces the osteosarcoma cell migration and invasion by regulating DNMT1 and suppresses osteosarcoma tumor growth in vivo.

  12. Oct4 is involved in DNA methylation through the regulation of Dnmt1 transcription, especially during the early stages of mouse pre-implantation embryo development.

  13. knockdown of DNMT1 in cerebellar granule neurons caused upregulation of some, but not all subtypes of MHC-I genes.

  14. Findings indicate that the steady-state level of DNMT1 protein in cycling cell populations is controlled at the level of transcription and that the interaction of DNMT1 and USP7 is unlikely to play a major role in DNMT1 homeostasis.

  15. Increased shear stress without a change in flow direction initiates arteriogenic growth; however, it also elicits DNMT1-dependent endothelial cells DNA hypermethylation. In turn, this diminishes mechanosensing, augments shear stress set point, and constrains the ultimate arteriogenic capacity of the vessel.

  16. Single-cell transcriptome analysis detected Dnmt1 expression in murine migratory GABAergic embryonic preoptic area (POA)-derived cells. Deletion of Dnmt1 in postmitotic immature cells of the POA caused defective migration and severely diminished adult cortical interneuron numbers. DNMT1 preserves the migratory shape in part through negative regulation of Pak6, which stimulates neuritogenesis postmigration.

  17. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1, DNMT3A, and DNMT3B proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  18. DNMT1 ablation from kidney proximal tubules enhanced cisplatin-induced acute kidney injury in mice, suggesting a renoprotective role of DNA methylation.

  19. Epigenetic enhancement of the post-replicative DNA mismatch repair of mammalian genomes by a Hemi-(m)CpG-Np95-Dnmt1 axis has been demonstrated for humans and mice.

  20. We show that expression of Id-1, a negative regulator of myogenesis, is enhanced in Dnmt1-deficient cultures, leading to enhanced transdifferentiation of myoblasts toward the osteogenic lineage. Thus, these studies demonstrate that Dnmt1 influences cellular identity and determines lineage fidelity.

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antigen Profile

Protein Summary

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DNMT1

  • DNA methyltransferase 1 (DNMT1) antibody
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) antibody
  • DNA methyltransferase 1 (Dnmt1) antibody
  • methyltransferase 1 (MET1) antibody
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) antibody
  • ADCADN antibody
  • AIM antibody
  • cb983 antibody
  • cb1075 antibody
  • Cxxc9 antibody
  • DDM2 antibody
  • DECREASED DNA METHYLATION 2 antibody
  • dmnt1 antibody
  • DMT01 antibody
  • DMT1 antibody
  • DNA METHYLTRANSFERASE antibody
  • DNA METHYLTRANSFERASE 01 antibody
  • DNA METHYLTRANSFERASE 1 antibody
  • Dnmt antibody
  • Dnmt1o antibody
  • fb05h01 antibody
  • HSN1E antibody
  • m.MmuI antibody
  • MCMT antibody
  • Met-1 antibody
  • Met1 antibody
  • MET2 antibody
  • methyltransferase 1 antibody
  • METHYLTRANSFERASE 2 antibody
  • METHYLTRANSFERASE I antibody
  • METI antibody
  • MommeD2 antibody
  • mta antibody
  • MTase antibody
  • wu:fb05h01 antibody

Protein level used designations for DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

GENE ID SPECIES
443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
Selected quality suppliers for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antibodies
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