DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody

Details for Product No. ABIN1724879
Antigen
Epitope
AA 1448-1594
56
49
28
25
21
18
17
16
15
15
15
15
8
7
7
7
6
5
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Monkey
404
160
71
54
49
3
2
2
2
1
1
1
1
1
1
Host
Mouse
301
98
8
7
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
27
21
21
16
16
16
10
10
10
10
10
10
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
244
144
97
73
71
60
53
47
33
30
28
6
4
4
3
2
2
2
1
1
1
Options
Immunogen Purified recombinant fragment of human DNMT1 (AA 1448-1594) expressed in E. Coli.
Clone 7C11A2
Isotype IgG1
Purification Purified
Antigen
Alternative Name DNMT1 (DNMT1 Antibody Abstract)
Background DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. , ,
Molecular Weight 183.2 kDa
Gene ID 1786
HGNC 1786
Pathways SARS-CoV-2 Protein Interactome
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (ABIN1724879) anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (Image 1)
Image no. 2 for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (ABIN1724879) anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (Image 2)
Image no. 3 for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (ABIN1724879) anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (Image 3)
Image no. 4 for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (ABIN1724879) anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (Image 4)
Image no. 5 for anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (ABIN1724879) anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody (Image 5)
Product cited in: He, Wang, Yang, Guo, Wan, Ke, Xu, Hu, Xu, Shen, Wang: "Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer." in: PLoS ONE, Vol. 6, Issue 11, pp. e27684, 2011 (PubMed).