anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) Antibodies

DRAM1 is regulated as part of the p53 tumor suppressor pathway. Additionally we are shipping DNA-Damage Regulated Autophagy Modulator 1 Kits (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DRAM1 55332 Q8N682
DRAM1 71712 Q9DC58
DRAM1 679937  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-DNA-Damage Regulated Autophagy Modulator 1 Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-DRAM Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>A549 cell lysate WB Suggested Anti-DRAM <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: A549 cell lysate <br /> DRAM1 is supported by BioGPS gene expression data to be expressed in A549 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Dram1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Small Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: DRAM Antibody [NBP1-76759] - Human liver tissue with DRAM antibody at 2.5 ug/ml. Western Blot: DRAM Antibody [NBP1-76759] - K562 cell lysate with DRAM antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. 0.1 mg Log in to see 8 to 11 Days
$485.88
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 2 to 3 Days
$325.00
Details
Human Rabbit Un-conjugated IHC, WB WB on PC12 cell lysate using Rabbit antibody to DRAM (Damage-regulated autophagy modulator): whole serum (ABIN350296) at 1 : 300 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band. IHC-P on human stomach-4 150 μL Log in to see 7 to 8 Days
$454.67
Details
Dog Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IHC (p), WB 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IHC (p), WB 50 μg Log in to see 6 to 8 Days
$390.50
Details

Top referenced anti-DNA-Damage Regulated Autophagy Modulator 1 Antibodies

  1. Human Polyclonal DRAM1 Primary Antibody for IHC (p), WB - ABIN2473364 : Watanabe, Abe, Tanaka, Takeuchi, Yasuura, Hikosaka, Suenaga, Hosokawa, Iwasa, Yamori: [Closure of ventricular septal defect of interrupted aortic arch with left ventricular outflow obstruction]. in Kyobu geka. The Japanese journal of thoracic surgery 1992 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal DRAM1 Primary Antibody for IHC, ELISA - ABIN1002228 : Crighton, Wilkinson, OPrey, Syed, Smith, Harrison, Gasco, Garrone, Crook, Ryan: DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. in Cell 2006 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal DRAM1 Primary Antibody for IHC, ELISA - ABIN1002229 : Gozuacik, Kimchi: Autophagy as a cell death and tumor suppressor mechanism. in Oncogene 2004 (PubMed)
    Show all 3 Pubmed References

More Antibodies against DNA-Damage Regulated Autophagy Modulator 1 Interaction Partners

Human DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) interaction partners

  1. Altogether, these findings suggest that in normal/high glucose condition a mutual unbalance between p53 (show TP53 Antibodies)-dependent apoptosis (PUMA (show BBC3 Antibodies)) and autophagy (DRAM) gene occurred, modifying the ADR (show AKR1B1 Antibodies)-induced cancer cell death in HG both in vitro and in vivo.

  2. Overexpression of full-length AIFM1 (show AIFM1 Antibodies) suppresses proliferation and induces apoptosis of HepG2 and Hep3B cells. Caspase 3 (show CASP3 Antibodies) and DRAM are involved in full-length AIFM1 (show AIFM1 Antibodies)-induced apoptosis in HepG2 and Hep3B cells.

  3. DRAM1 regulates apoptosis by inhibiting BAX (show BAX Antibodies) degradation.

  4. DRAM1 mediates autophagic defense against a broader range of intracellular pathogens, since DRAM1 expression was also induced by the common bacterial endotoxin lipopolysaccharide.

  5. Suggest that promoting DRAM-mediated autophagy together with PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) inhibition might be more effective for autophagy-based therapy in hepatoma.

  6. DRAM is an important gene for the enhancement of p53 (show TP53 Antibodies)-dependent apoptosis.

  7. DRAM1 affects autophagy through lysosomal acidification, fusion of lysosomes with autophagosomes and clearance of autophagosomes.

  8. DRAM gene expression is down regulated by oxidative stress through the mediation of reactive oxygen species

  9. DRAM triggers lysosomal membrane permeabilization and cell death in CD4 (show CD4 Antibodies)(+) T cells infected with HIV.

  10. these findings shed new light on the role of autophagy in GBM and reveal a novel function of the autophagy regulators DRAM1 and p62 in control of migration/invasion in cancer stem cells.

Mouse (Murine) DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) interaction partners

  1. DRAM1 knockdown aggravates OGD (show FGFR1 Antibodies)/R-induced cell injury.

  2. DRAM-1 encodes not just one mRNA, but a series of p53 (show TP53 Antibodies)-inducible splice variants which are expressed at varying levels in multiple human and mouse cell lines.

DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) Antigen Profile

Protein Summary

This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.

Gene names and symbols associated with DRAM1

  • DNA damage regulated autophagy modulator 1 (DRAM1) antibody
  • DNA-damage regulated autophagy modulator 1 (Dram1) antibody
  • DNA damage regulated autophagy modulator 1 L homeolog (dram1.L) antibody
  • 1200002N14Rik antibody
  • dram antibody
  • DRAM1 antibody

Protein level used designations for DRAM1

DNA-damage regulated autophagy modulator 1 , DNA damage-regulated autophagy modulator protein 1 , damage-regulated autophagy modulator , Damage-regulated autophagy modulator

GENE ID SPECIES
418095 Gallus gallus
612179 Canis lupus familiaris
100462750 Sus scrofa
55332 Homo sapiens
71712 Mus musculus
679937 Rattus norvegicus
533992 Bos taurus
431986 Xenopus laevis
Selected quality suppliers for anti-DNA-Damage Regulated Autophagy Modulator 1 (DRAM1) Antibodies
Did you look for something else?