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Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay.
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Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
decapping enzyme, scavenger
, decapping scavenger enzyme
, heat shock-like protein 1
, hint-related 7meGMP-directed hydrolase
, histidine triad nucleotide-binding protein 5
, histidine triad protein member 5
, homolog of C. elegans 7meGMP-directed hydrolase dcs-1
, m7GpppX diphosphatase
, mRNA decapping enzyme
, scavenger mRNA-decapping enzyme DcpS