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Potential guanine nucleotide exchange factor (GEF).
Showing 7 out of 9 products:
Human Polyclonal DOCK10 Primary Antibody for IP, WB - ABIN253140
Matsuda, Yanase, Takaoka, Maruyama: The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. in Immunity & ageing : I & A 2015
T cells and B cells exhibited inverse expression patterns of the DOCK10 isoforms
Dock10 could represent a point of convergence for interleukin 4 (show IL4 Antibodies) signalling and small Rho GTPase (show RACGAP1 Antibodies) function in B cells.
Silencing DOCK10 expression in melanoma promotes conversion to mesenchymal migration and is associated with decreased MLC2 phosphorylation and increased Rac1 activation.
Dock10 negatively regulates membrane CD23 (show FCER1G Antibodies) expression; negative regulation of CD23 (show FCER1G Antibodies) expression by Dock10 could play a role in B cell maturation (show TNFRSF17 Antibodies) and function
DOCK10 function in dendritic spine morphogenesis is mediated mainly by Cdc42 and its downstream effectors N-WASP and PAK3, although DOCK10 is also able to activate Rac1.
Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP.
dedicator of cytokinesis protein 10
, dedicator of cytokinesis 10
, dedicator of cytokinesis protein 10-like
, dopamine receptor interacting protein 2
, protein zizimin 3