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DCD encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. Additionally we are shipping Dermcidin Kits (15) and Dermcidin Proteins (8) and many more products for this protein.
Showing 10 out of 66 products:
Human Monoclonal DCD Primary Antibody for IA, IHC (p) - ABIN2191909
Sagawa, Kimura, Saito, Inoue, Yasuda, Nosaka, Tsuji: Production and characterization of a monoclonal antibody for sweat-specific protein and its application for sweat identification. in International journal of legal medicine 2003
Show all 2 Pubmed References
The results of this study suggest that these biomarker DCD can serve as a potential non-invasive early diagnosis platform reflecting PiB-PET imaging for Mild Cognitive Impairment and Alzheimer's Disease.
this study shows that PIF (show PIF1 Antibodies) regulates systemic immunity and targets protective regulatory and cytoskeleton proteins
This is the first report of the presence of DCD in nasal mucosa and demonstration of DCD in clinical samples of human nasal secretions at clinically relevant concentrations, which may represent a novel arm of sinonasal airway innate defense.
Identification of dermcidin in human sebaceous gland cells supports the concept that sebocytes play an important role in the innate immunity of the skin through the expression of antimicrobial peptides and specific lipids.
Reduced DCD concentration in sweat in patients with inflammatory acne may permit proliferation of P. acnes in pilosebaceous units, resulting in progression of inflammatory acne.
These findings imply that DCD promotes breast tumorigenesis via modulation of ERBB (show EGFR Antibodies) signaling pathways
Dermcidin binds platelets and may inhibit the therapeutic action of aspirin following acute myocardial infarction.
Data indicate that Y-P30 (show CENPV Antibodies)/dermcidin expressed in placentas of first trimester pregnancies.
Increased Dermcidin was also detected with immunoblotting.
major binding partners of LEKTI (show SPINK5 Antibodies) were found to be the antimicrobial peptide (show CAMP Antibodies) dermcidin and the serine protease (show F2 Antibodies) cathepsin G (show CTSG Antibodies) and no kallikreins.
This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
, diffusible survival/evasion peptide
, proteolysis inducing factor
, survival promoting peptide