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DFFB Antibodies

(DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB))
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined. [provided by RefSeq, Jul 2008].
anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (AA 1-30), (N-Term) antibody anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (AA 1-30), (N-Term) antibody anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (AA 1-30), (N-Term) antibody (ABIN653798)

DFFB Reactivity: Human FACS, IHC (p), WB Host: Rabbit Polyclonal RB24419 unconjugated

anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (N-Term) antibody anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (N-Term) antibody anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (N-Term) antibody (ABIN6655306)

DFFB Reactivity: Human ELISA, FM, IHC, WB Host: Rabbit Polyclonal unconjugated

anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (Middle Region) antibody anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (Middle Region) antibody anti-DNA Fragmentation Factor, 40kDa, beta Polypeptide (Caspase-Activated DNase) (DFFB) (Middle Region) antibody (ABIN1030918)

DFFB Reactivity: Human, Mouse, Rat ICC, ELISA, WB Host: Rabbit Polyclonal unconjugated

DFFB Antibodies by Reactivity

Find DFFB Antibodies for a variety of species such as anti-Human DFFB, anti-Mouse DFFB, anti-Rat DFFB. The species listed below are among those available. Click on a link to go to the corresponding products.

DFFB Antibodies by Application

Find DFFB Antibodies validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

DFFB Antibodies by Host

Find DFFB Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

DFFB Antibodies by Binding Specificity

Find DFFB Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

DFFB Antibodies by Clonality

Find available monoclonal or polyclonal DFFB Antibodies. Click on a link to go to the corresponding products.

DFFB Antibodies by Clone

Find DFFB Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

DFFB Antibodies by Conjugate

Find DFFB Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular DFFB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN560596
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN514957
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN307617
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application EIA, IF, WB
Validations
  • (2)
Cat. No. ABIN499738
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IF, WB
Validations
  • (2)
Cat. No. ABIN499740
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application EIA, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN499517
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, WB
Validations
  • (1)
Cat. No. ABIN1858217
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
Cat. No. ABIN724085
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
  • (1)
Cat. No. ABIN872776
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN2707475
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN208001
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ICC, WB
Validations
  • (1)
Cat. No. ABIN203319
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Mouse
Application IHC, WB
Validations
  • (1)
Cat. No. ABIN201898
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN187821
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN187738
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DFFB Antibodies

Yoon, Park, Han, Kang, Kim, Lee, Park, Shin, Kim, Yun, Chwae: "Caspase-dependent cell death-associated release of nucleosome and damage-associated molecular patterns." in: Cell death & disease, Vol. 5, pp. e1494, (2014) (PubMed).

Kumar, Kant, Singh et al.: "Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage ..." in: Toxicology and applied pharmacology, Vol. 273, Issue 1, pp. 196-208, (2013) (PubMed).

Nagata: "DNA degradation in development and programmed cell death." in: Annual review of immunology, Vol. 23, pp. 853-75, (2005) (PubMed).

Kanouchi, Nishizaki, Minatogawa, Toné: "Large complex formation of the inhibitor of caspase-activated DNase." in: Apoptosis : an international journal on programmed cell death, Vol. 10, Issue 3, pp. 651-6, (2005) (PubMed).

Nagata, Nagase, Kawane, Mukae, Fukuyama: "Degradation of chromosomal DNA during apoptosis." in: Cell death and differentiation, Vol. 10, Issue 1, pp. 108-16, (2003) (PubMed).

Yoshida, Urasaki, Waltham, Bergman, Pourquier, Rothwell, Inuzuka, Weinstein, Ueda, Appella, Hickson, Pommier: "Human apurinic/apyrimidinic endonuclease (Ape1) and its N-terminal truncated form (AN34) are involved in DNA fragmentation during apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37768-76, (2003) (PubMed).

Wid?ak: "The DFF40/CAD endonuclease and its role in apoptosis." in: Acta biochimica Polonica, Vol. 47, Issue 4, pp. 1037-44, (2002) (PubMed).

Liu, Zou, Widlak, Garrard, Wang: "Activation of the apoptotic endonuclease DFF40 (caspase-activated DNase or nuclease). Oligomerization and direct interaction with histone H1." in: The Journal of biological chemistry, Vol. 274, Issue 20, pp. 13836-40, (1999) (PubMed).

Enari, Sakahira, Yokoyama, Okawa, Iwamatsu, Nagata: "A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD." in: Nature, Vol. 391, Issue 6662, pp. 43-50, (1998) (PubMed).

Liu, Li, Widlak, Zou, Luo, Garrard, Wang: "The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 15, pp. 8461-6, (1998) (PubMed).

Aliases for DFFB Antibodies

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD) Antibodies
DNA fragmentation factor subunit beta (DFFB) Antibodies
DNA fragmentation factor, beta polypeptide (caspase-activated DNase) (dffb) Antibodies
DNA fragmentation factor subunit beta (LOC100223514) Antibodies
DNA fragmentation factor, beta subunit (Dffb) Antibodies
DNA fragmentation factor subunit beta (Dffb) Antibodies
40kDa Antibodies
5730477D02Rik Antibodies
CAD Antibodies
Cad Antibodies
CPAN Antibodies
DFF-40 Antibodies
DFF2 Antibodies
DFF40 Antibodies
Didff Antibodies
LOC100223514 Antibodies
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