Dihydrolipoyl Transacetylase Proteins (DLAT)

DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). Additionally we are shipping Dihydrolipoyl Transacetylase Antibodies (55) and Dihydrolipoyl Transacetylase Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DLAT 1737 P10515
DLAT 81654 P08461
DLAT 235339 Q8BMF4
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Top Dihydrolipoyl Transacetylase Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$640.00
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$736.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$554.07
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,589.67
Details

DLAT Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus)

Mouse (Murine) ,

More Proteins for Dihydrolipoyl Transacetylase (DLAT) Interaction Partners

Human Dihydrolipoyl Transacetylase (DLAT) interaction partners

Zebrafish Dihydrolipoyl Transacetylase (DLAT) interaction partners

Mouse (Murine) Dihydrolipoyl Transacetylase (DLAT) interaction partners

Dihydrolipoyl Transacetylase (DLAT) Protein Profile

Protein Summary

This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.

Gene names and symbols associated with DLAT

  • midline uncoordinated (muc)
  • dihydrolipoamide S-acetyltransferase L homeolog (dlat.L)
  • dihydrolipoamide S-acetyltransferase (DLAT)
  • dihydrolipoamide S-acetyltransferase (Dlat)
  • dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (dlat)
  • dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (Dlat)
  • 6332404G05Rik protein
  • anon-WO0118547.121 protein
  • DLAT protein
  • DLTA protein
  • Dmel\\CG5261 protein
  • EP(2)0816 protein
  • EP816 protein
  • PDC-E2 protein
  • PDCE2 protein
  • wu:fc14f10 protein
  • wu:fc21f08 protein
  • wu:fc86g11 protein
  • wu:fj57d06 protein

Protein level used designations for DLAT

CG5261-PA , CG5261-PB , CG5261-PC , CG5261-PD , CG5261-PE , CG5261-PF , Dihydrolipoyllysine-residue acetyltransferase , dihydrolipoamide acetyltransferase , dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) , 70 kDa mitochondrial autoantigen of primary biliary cirrhosis , E2 component of pyruvate dehydrogenase complex , M2 antigen complex 70 kDa subunit , PBC , dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex , dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial , dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial , pyruvate dehydrogenase complex component E2 , dihydrolipoyllysine-residue acetyltransferase , E2 , PDC-E2 , PDCE2 , fc86g11 , fj57d06 , no optokinetic nystagmus a , no optokinetic response b , noa , nrb

GENE ID SPECIES
34021 Drosophila melanogaster
398314 Xenopus laevis
419796 Gallus gallus
1737 Homo sapiens
489406 Canis lupus familiaris
397054 Sus scrofa
512723 Bos taurus
81654 Rattus norvegicus
100349212 Oryctolagus cuniculus
324201 Danio rerio
235339 Mus musculus
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