Dimethylarginine Dimethylaminohydrolase 2 Proteins (DDAH2)

DDAH2 belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. Additionally we are shipping DDAH2 Antibodies (60) and DDAH2 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDAH2 23564 O95865
DDAH2 51793 Q99LD8
DDAH2 294239 Q6MG60
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Top DDAH2 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days

DDAH2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) Interaction Partners

Human Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) interaction partners

  1. genetic variations in the DDAH2 gene may influence the ADMA concentration and erythropoietin (show EPO Proteins) resistance in MHD patients

  2. The main finding from this study was that it demonstrated that the C-allele of rs3087894 in DDAH1 is a risk factor for hypertension in the Kazakh group but a protective factor in the Uygur group. In addition, we did not find any genotype of DDAH1 and DDAH2 associated with hypertension in the Han group.

  3. Exogenous human DDAH2 gene promotes differentiation of rabbit bone marrow-derived endothelial progenitor cells into mature endothelial cells.

  4. expression of DDAH2 is associated with invasiveness of lung adenocarcinoma via tumor angiogenesis

  5. Inhibiting the expression of DDAH1 (show DDAH1 Proteins), but not DDAH2, resulted in a significant increase in the sensitivity of the EVT cell line SGHPL-4 to tumour necrosis factor (show TNF Proteins) related apoptosis inducing ligand (TRAIL) induced apoptosis

  6. increased ADMA levels in rheumatoid arthritis do not appear to relate to DDAH genetic polymorphisms

  7. The percentage of senescent endothelial progenitor cells increased while the expression of DDAH2 decreased concomitantly with an increase in the plasma levels of asymmetric dimethylarginine in patients with type 2 diabetes mellitus.

  8. DDAH-1 (show DDAH1 Proteins) is a specific molecular target for portal pressure reduction, through actions on ADMA-mediated regulation of eNOS (show NOS3 Proteins) activity.

  9. Our results suggest that the rs805304 C allele of the DDAH gene was associated with decreased risk of myocardial infarction and decreased risk of obesity.

  10. Homocysteine disrupts EPCs function via inducing the hypermethylation of DDAH2 promoter, suggesting a key role of epigenetic mechanism in the progression of atherosclerosis

Mouse (Murine) Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) interaction partners

  1. We conclude that pp60(Src (show SRC Proteins)) can directly inhibit DDAH II and this is involved in the increased ADMA levels that enhance eNOS (show NOS3 Proteins) uncoupling during the development of acute lung injury (ALI).

  2. In mild CKD, dysregulation of the ADMA/DDAH pathway in adipose tissue triggers lipodystrophy-like phenotype changes, including ectopic fat depositions.

  3. The Sirt1 (show SIRT1 Proteins)/DDAH2/secretagogin (show SCGN Proteins) pathway is a novel regulator of glucose-stimulated insulin (show INS Proteins) secretion.

  4. DDAH2/ADMA pathway can be a novel therapeutic target for vasculopathy in the ADMA or angiotensin II-induced pathophysiological conditions

  5. Report tissue-specific downregulation of DDAH2 in hyperhomocysteinemia.

  6. Results show that asymmetric methylarginine increases pulmonary endothelial permeability, and that its effects on permeability, Rac1 activation and VASP (show VASP Proteins) phosphorylation are prevented by overexpression of active DDAHI (show DDAH1 Proteins) and DDAHII.

  7. ADMA and nitrosative stress are related to increased expression of protein-arginine methyltransferase-2 (show PRMT2 Proteins), an ADMA-synthesizing enzyme, and reduced expression of dimethylarginine dimethylaminohydrolase-2, an ADMA-degrading enzyme, in bronchial epithelia

DDAH2 Protein Profile

Protein Summary

This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.

Gene names and symbols associated with DDAH2

  • dimethylarginine dimethylaminohydrolase 2 (ddah2)
  • dimethylarginine dimethylaminohydrolase 2 L homeolog (ddah2.L)
  • dimethylarginine dimethylaminohydrolase 2 (DDAH2)
  • dimethylarginine dimethylaminohydrolase 2 (Ddah2)
  • 1110003M04Rik protein
  • AU019324 protein
  • AW413173 protein
  • Ddah protein
  • DDAH-2 protein
  • DDAH2 protein
  • DDAHII protein
  • G6a protein
  • MGC84290 protein
  • MGC89103 protein
  • NG30 protein

Protein level used designations for DDAH2

NG,NG-dimethylarginine dimethylaminohydrolase 2 , dimethylarginine dimethylaminohydrolase 2 , DDAH-2 , N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 , NG-dimethylarginine dimethylamino hydrolase homolog , S-phase protein , alternative name: NG30, G6a , dimethylargininase-2 , dimethylarginine dimethylaminohydrolase II , protein G6a , Clone 7u , DDAHII

100194775 Salmo salar
447573 Xenopus laevis
448306 Xenopus (Silurana) tropicalis
716356 Macaca mulatta
745121 Pan troglodytes
23564 Homo sapiens
51793 Mus musculus
474846 Canis lupus familiaris
540386 Bos taurus
294239 Rattus norvegicus
100720724 Cavia porcellus
100352259 Oryctolagus cuniculus
101118391 Ovis aries
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