Dipeptidyl-Peptidase 6 Proteins (DPP6)

DPP6 encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. Additionally we are shipping DPP6 Antibodies (68) and DPP6 Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DPP6 1804 P42658
DPP6 13483 Q9Z218
DPP6 29272 P46101
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Top DPP6 Proteins at antibodies-online.com

Showing 7 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 60 to 65 Days
$7,639.51
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 60 to 65 Days
$10,888.92
Details
Yeast Rat His tag Dipeptidyl-Peptidase 6 (DPP6) (AA 111-859) protein (His tag) Protein expressed in E.coli. 500 μg Log in to see 60 to 71 Days
$1,155.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 2 to 3 Days
$814.00
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Yeast Rat His tag   100 μg Log in to see 8 to 11 Days
$578.60
Details
Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 11 Days
$581.90
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human DPP6 Protein. 100 μg Log in to see 11 to 18 Days
$611.18
Details

DPP6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)
,
Rat (Rattus) ,

More Proteins for Dipeptidyl-Peptidase 6 (DPP6) Interaction Partners

Human Dipeptidyl-Peptidase 6 (DPP6) interaction partners

  1. These data suggest that the proband's autism may be due to the inheritance of disruptions in both DPP6 and LRRC4C (show LRRC4C Proteins), and may highlight the importance of the netrin G family and potassium channel (show KCNAB2 Proteins) interacting molecules in neurodevelopmental disorders.

  2. we expanded our knowledge of familial IVF (show SCN5A Proteins) linked to the DPP6 gene and discuss its (extended) clinical characteristics. In addition, its relationship with the Purkinje network is further explored.

  3. This first familial case provides evidence for association between DPP6 haploinsufficiency and Gilles de la Tourette syndrome.

  4. the cysteine-rich domain of DPP6 plays an important role in protein folding of DPP6 that is required for transport of DPP6/Kv4.2 (show KCND2 Proteins) complexes out of the ER

  5. DPP6 is critical for synaptic integration and excitation.

  6. Two DPP6 de novo deletions and one missense mutation in familial microcephalic patients were identified.

  7. WT PrP(C (show PRNP Proteins)), in a DPP6-dependent manner, modulated Kv4.2 (show KCND2 Proteins) channel properties, causing an increase in peak amplitude

  8. Findings of this study indicate that an altered response of Kv4 (show KCNC1 Proteins)/DPP6 to long-term neuroleptic administration is involved in neuroleptic-induced TD.

  9. DPP6-mediated Purkinje fibers early-repolarization syndrome might be a novel molecular paradigm for some forms of idiopathic ventricular fibrillation.

  10. Antibodies to DPPX are associated with a protracted encephalitis characterized by central nervous system hyperexcitability.

Mouse (Murine) Dipeptidyl-Peptidase 6 (DPP6) interaction partners

  1. expression pattern of DPP6 suggests that it may be involved in mandible and tooth development.

  2. Dipeptidyl-peptidase 6 has an unexpected but important role in cell adhesion and motility, impacting the hippocampal synaptic development and function.

  3. WT PrP(C (show PRNP Proteins)), in a DPP6-dependent manner, modulated Kv4.2 (show KCND2 Proteins) channel properties, causing an increase in peak amplitude

  4. Findings of this study indicate that an altered response of Kv4 (show KCNC1 Proteins)/DPP6 to long-term neuroleptic administration is involved in neuroleptic-induced TD.

  5. DPP6 co-expression with TASK-3 (show KCNK9 Proteins) results in the formation of a protein complex that enhances resting membrane potassium conductance.

  6. the present study described epigenetic silencing of Dpp6 expression by DNA methylation and established that its ectopic expression can act as negative signal during RA induced neuronal differentiation of P19 cells.

  7. In the presence of DPP6 or DPP10, cell surface Kv4.2 (show KCND2 Proteins) protein expression is selectively increased.

  8. The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.

  9. The DPP6-E is selectively expressed in a few neuronal populations in brain including cerebellar granule neurons, hippocampal pyramidal cells and neurons in intermediary layers of the superior colliculus.

  10. DPP6 is necessary and sufficient to explain the larger unitary conductance of neuronal Kv4 (show KCNC1 Proteins) channels underlying the neuronal subthreshold-operating A-type potassium (K+) current.

DPP6 Protein Profile

Protein Summary

This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with Dipeptidyl-Peptidase 6 Proteins (DPP6)

  • dipeptidyl peptidase like 6 (DPP6)
  • dipeptidyl-peptidase 6 (dpp6)
  • dipeptidyl-peptidase 6 (BCAN_A2221)
  • dipeptidyl-peptidase 6 (BSUIS_A2016)
  • dipeptidyl-peptidase 6 (Bsph_2289)
  • dipeptidyl-peptidase 6 (BMEA_A2239)
  • dipeptidyl-peptidase 6b (dpp6b)
  • dipeptidylpeptidase 6 (Dpp6)
  • dipeptidyl peptidase like 6 (Dpp6)
  • B930011P16Rik protein
  • D5Buc3 protein
  • D5Buc4 protein
  • D5Buc5 protein
  • Dpp-6 protein
  • dpp6 protein
  • DPP VI protein
  • DPPX protein
  • Gm1377 protein
  • In(5)6H-p protein
  • Peplb protein
  • Rw protein
  • si:ch211-198f16.1 protein
  • VF2 protein

Protein level used designations for Dipeptidyl-Peptidase 6 Proteins (DPP6)

dipeptidyl-peptidase 6 , DPP VI , dipeptidyl aminopeptidase IV-related protein , dipeptidyl aminopeptidase-like protein 6 , dipeptidyl aminopeptidase-related protein , dipeptidyl peptidase 6 , dipeptidyl peptidase IV-like protein , dipeptidyl peptidase IV-related protein , dipeptidyl peptidase VI , dipeptidylpeptidase 6 , dipeptidylpeptidase VI , DPPX , inversion, Chr 5, Harwell 6, proximal

GENE ID SPECIES
475553 Canis lupus familiaris
420440 Gallus gallus
100016139 Monodelphis domestica
100125080 Xenopus (Silurana) tropicalis
100225294 Taeniopygia guttata
100344997 Oryctolagus cuniculus
5785486 Brucella canis ATCC 23365
5838315 Brucella suis ATCC 23445
6023942 Lysinibacillus sphaericus C3-41
7676721 Brucella melitensis ATCC 23457
1804 Homo sapiens
281123 Bos taurus
463835 Pan troglodytes
566832 Danio rerio
13483 Mus musculus
29272 Rattus norvegicus
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