anti-Discs, Large Homolog 5 (Drosophila) (DLG5) Antibodies

DLG5 encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. Additionally we are shipping DLG5 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DLG5 9231 Q8TDM6
DLG5 71228  
DLG5 305645  
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Top anti-DLG5 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Rabbit Un-conjugated IP, WB 100 μL Log in to see 7 to 9 Days
$556.31
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DLG5 is 3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.96 KDa) . 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.33 KDa) . 50 μL Log in to see 11 to 12 Days
$305.71
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
$837.83
Details
Human Rabbit Un-conjugated ICC, IF Immunocytochemistry/Immunofluorescence: DLG5 Antibody  - Staining of human cell line HaCaT shows localization to cell junctions. 100 μL Log in to see 10 to 13 Days
$491.63
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Used in DAB staining on fromalin fixed paraffin- embedded brain tissue 100 μg Log in to see 15 to 18 Days
$350.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human PC3 cell lysate; Primary Ab: 2µg/ml Rabbit Anti-Mouse DLG5 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg Log in to see 15 to 18 Days
$360.00
Details
Cow Rabbit Un-conjugated IP, WB   100 μL Log in to see 7 to 9 Days
$595.83
Details
Guinea Pig Rabbit Un-conjugated IP   100 μL Log in to see 7 to 9 Days
$595.83
Details

DLG5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against DLG5 Interaction Partners

Human Discs, Large Homolog 5 (Drosophila) (DLG5) interaction partners

  1. Low expression of DLG5 is associated with Crohn's disease.

  2. Data found that Dlg5 expression was significantly lower in human hepatocellular carcinoma (HCC (show FAM126A Antibodies)) tissues and indicate that Dlg5 acts as a novel regulator of invadopodium-associated invasion via Girdin (show CCDC88A Antibodies) and by interfering with the interaction between Girdin (show CCDC88A Antibodies) and Tks5 (show SH3PXD2A Antibodies), which might be important for Tks5 (show SH3PXD2A Antibodies) phosphorylation in HCC (show FAM126A Antibodies) cells.

  3. DLG5 inhibits the association between MST1 (show MST1 Antibodies)/2 and large tumor suppressor (show LATS1 Antibodies) homologs 1/2 (LATS1 (show LATS1 Antibodies)/2), uses its scaffolding function to link MST1 (show MST1 Antibodies)/2 with MARK3 (show MARK3 Antibodies), and inhibits MST1 (show MST1 Antibodies)/2 kinase activity

  4. study has identified several new proteins like RHOC (show RHOC Antibodies), DLG5, UGDH (show UGDH Antibodies), TMOD3 (show TMOD3 Antibodies) in addition to known chemoresistance associated proteins in non-small cell lung carcinoma.

  5. These data suggest that inhibition of Dlg5 by DNA hypermethylation contributes to provoke invasive phenotypes in bladder tumor.

  6. Findings demonstrate that Dlg5 interacts with and inhibits the activity of Girdin (show CCDC88A Antibodies), thereby suppressing the migration of prostate cancer cells.

  7. DLG5 plays a role in cell migration, cell adhesion, precursor cell division, cell proliferation, epithelial cell polarity maintenance, and transmission of extracellular signals to the membrane and cytoskeleton.

  8. Overexpression of Dlg5 enhances the degradation of TGFBRI.

  9. Polymorphisms in the DLG5 gene were found to be associated with Crohn's disease patients in Malaysia.

  10. Examined the genetic association of DLG5 SNP P1371Q with inflammatory bowel disease and its interaction with R30Q in disease susceptibility. P1371Q is complementary to R30Q, with R30Q exhibiting a dominant effect in IBD susceptibility.

Mouse (Murine) Discs, Large Homolog 5 (Drosophila) (DLG5) interaction partners

  1. Dlg5 is required for Hh-induced enrichment of Kif7 (show KIF7 Antibodies) and Gli2 (show GLI2 Antibodies) at the tip of the cilium but is dispensable for Gpr161 (show GPR161 Antibodies) exit from the cilium and the consequent suppression of Gli3 (show GLI3 Antibodies) processing into its repressor form

  2. DLG5 is a MAGUK protein that regulates spine formation, synaptogenesis, and synaptic transmission in cortical neurons.

  3. Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.

  4. Data report that Discs large (show DLG4 Antibodies) 5 (Dlg5), a member of the MAGUK family, is an interactor of CitK required for CitK polarization.

DLG5 Antigen Profile

Protein Summary

This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined.

Gene names and symbols associated with DLG5

  • discs large MAGUK scaffold protein 5 (DLG5) antibody
  • discs, large homolog 5 (Drosophila) (DLG5) antibody
  • discs, large homolog 5a (Drosophila) (dlg5a) antibody
  • discs, large homolog 5 (Drosophila) (Dlg5) antibody
  • discs large MAGUK scaffold protein 5 (Dlg5) antibody
  • 4933429D20Rik antibody
  • dlg5 antibody
  • LP-DLG antibody
  • mKIAA0583 antibody
  • P-DLG5 antibody
  • PDLG antibody
  • T25557 antibody
  • wu:fc28f03 antibody

Protein level used designations for DLG5

discs, large homolog 5 (Drosophila) , discs large homolog 5 , discs large protein , discs, large homolog 5 , disks large homolog 5 , discs large protein LP-DLG , discs large protein P-dlg , large type of P-DLG , placenta and prostate DLG

GENE ID SPECIES
703123 Macaca mulatta
423728 Gallus gallus
535699 Bos taurus
489061 Canis lupus familiaris
448848 Sus scrofa
569065 Danio rerio
100225167 Taeniopygia guttata
9231 Homo sapiens
71228 Mus musculus
305645 Rattus norvegicus
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