Dual Oxidase 1 (DUOX1) ELISA Kits

The protein encoded by DUOX1 is a glycoprotein and a member of the NADPH oxidase family. Additionally we are shipping DUOX1 Antibodies (43) and DUOX1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DUOX1 53905 Q9NRD9
Anti-Mouse DUOX1 DUOX1 99439  
DUOX1 266807 Q8CIY2
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Top DUOX1 ELISA Kits at antibodies-online.com

Showing 4 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rat < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Pig
  96 Tests Log in to see 15 to 18 Days
$1,029.60
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Dog
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

More ELISA Kits for DUOX1 Interaction Partners

Purple Sea Urchin (Strongylocentrotus purpuratus) Dual Oxidase 1 (DUOX1) interaction partners

  1. dual oxidase Udx1 has a role in the oxidative burst at fertilization

Zebrafish Dual Oxidase 1 (DUOX1) interaction partners

  1. The duox expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization.

  2. The results reveal a crucial role for TNFalpha/TNFR2 axis in the protection of the skin against DUOX1-mediated oxidative stress.

  3. extracellular ATP acting as an early danger signal is responsible for the activation of Duox1 via a P2YR/PLC/Ca(2+) signaling pathway and the production of H2O2

  4. Zebrafish duox is highly expressed in intestinal epithelial cells. Knockdown of Duox impaired larval capacity to control enteric Salmonella infection.

Human Dual Oxidase 1 (DUOX1) interaction partners

  1. Authors demonstrate here that DUOX1 is silenced in breast cancer, which seems to be involved in breast carcinogenesis.

  2. Silencing DUOX1 by siRNA attenuated IL-13-mediated increases in superoxide, but did not reduce autophagy activities.

  3. We analyzed the expression of NADPH oxidase isoforms and found both A431 and HaCaT cells to express the calcium-sensitive NADPH oxidase, Dual oxidase 1 (Duox1) and its protein partner Duox activator 1 (DuoxA1).Our observations provide evidence for a new signaling paradigm in which changes of intracellular calcium concentration are transformed into redox signals through the calcium-dependent activation of Duox1.

  4. DUOX1 missense mutation plays a role in congenital hypothyroidism.

  5. Our findings implicate epithelial DUOX1 as a pivotal mediator of IL-33-dependent activation of innate airway type 2 immune responses to common airborne allergens and indicate that enhanced DUOX1 expression and IL-33 secretion might present important contributing features of allergic asthma.

  6. Cox multivariate regression analysis demonstrated that DUOX1, GLS2, FBP1 and age were independent risk factors for the prognosis of HCC patients after surgery

  7. DUOX1 expression in liver tumors is a potential prognostic tool for patients.

  8. Nox4 and Duox1/Duox2 mediate redox activation of mesenchymal cell migration by PDGF.

  9. These data reveal a key role of DUOX1-dependent hydrogen peroxide production in long-term persistent radio-induced DNA damage.

  10. Studies demonstrate the importance of DUOX1 in epithelial redox signaling through reversible S-glutathionylation of a range of proteins, including proteins involved in cytoskeletal regulation and MAPK signaling pathways involved in cell migration.

  11. Duox2 proteins possessing the A-loops of Nox1 or Nox5 co-expressed with DuoxA2 showed enhanced O2 () release, and Duox1 proteins possessing the A-loops of Nox1 or Nox5 co-expressed with DuoxA1 acquired O2 () leakage

  12. DUOX1 is the major H2O2-producing source in NHKs stimulated with Ca(2+), and plays a significant role in regulating the expression of specific markers necessary for the normal differentiation of keratinocytes

  13. Further, ROS generated by Duox enzymes localized adjacent to nuclear speckles altered the splicing of viral genes

  14. Despite the high sequence similarity shared between DUOX1 and DUOX2, the two isoforms present distinct regulations, tissue expression and catalytic functions

  15. Duox1 activity is stimulated by testosterone through GPRC6A in skin keratinocytes

  16. Underscore the importance of DUOX1 and DUOX2 in vesicant-induced IL-6 secretion in human airway epithelial cells.

  17. upregulated in chronic rhinosinusitis as a part of inflammatory response

  18. PA-LPS-induced MUC5AC and Clca3 expression is partly through Duox1

  19. DUOX1 plays a central role in epithelial defense responses to infection or injury, by mediating oxidative activation of Src and ADAM17 in response to ATP-dependent P2Y(2)R activation as a proximal step in EGFR transactivation and downstream signaling.

  20. Report shows that ROS levels in PC3 cells are constitutively maintained by DUOX 1 and 2 enzymes, and these ROS positively regulate AKT signalling through inactivating phosphatases, leading to increased resistance to apoptosis.

Mouse (Murine) Dual Oxidase 1 (DUOX1) interaction partners

  1. Cigarette smoke impairs A2A adenosine receptor mediated wound repair through up-regulation of Duox-1 expression.

  2. Reactive Oxygen Species levels were elevated and DUOX1 expression was increased 70-fold in OVA-allergen challenged lungs.

  3. Data, including data from studies using transgenic mice, suggest that over-expression of IL4 (interleukin 4) in thyroid tissue/cells up-regulates expression of Duox1 (dual oxidase 1), Duoxa1 (dual oxidase maturation factor 1), and Slc26a4 (pendrin) in thyroid tissue/cells; expression of Slc5a5 (sodium-iodide symporter) is down-regulated.

  4. Redox-dependent regulation of EGFR activation in airway epithelial cells was found to strongly depend on activation of either DUOX1 or NOX2.

  5. Our findings implicate epithelial DUOX1 as a pivotal mediator of IL-33-dependent activation of innate airway type 2 immune responses to common airborne allergens and indicate that enhanced DUOX1 expression and IL-33 secretion might present important contributing features of allergic asthma.

  6. findings suggest that LPS-TLR-4-induced KC or MIP-2 cytokine induction and subsequent neutrophil recruitment in the airway does not require DUOX-derived hydrogen peroxide from airway epithelium

  7. These findings suggest that DUOX-derived H2O2 has an important role in signaling neutrophils into allergic airways

  8. Studies demonstrate the importance of DUOX1 in epithelial redox signaling through reversible S-glutathionylation of a range of proteins, including proteins involved in cytoskeletal regulation and MAPK signaling pathways involved in cell migration.

  9. PA-LPS-induced MUC5AC and Clca3 expression is partly through Duox1

  10. In vivo DUOX1 silencing significantly suppressed naphthalene-induced activation of STAT3.

  11. Urothelial cells produce hydrogen peroxide through the activation of Dual oxidase 1

  12. Duox1 is the main source of H(2)O(2) in the rat thyroid cell line PCCl3.

DUOX1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene names and symbols associated with Dual Oxidase 1 (DUOX1) ELISA Kits

  • dual oxidase 1 (duox1) antibody
  • dual oxidase 1 (DUOX1) antibody
  • dual oxidase (duox) antibody
  • dual oxidase (LOC5569378) antibody
  • dual oxidase 1 (Duox1) antibody
  • 9930101G15Rik antibody
  • AW987690 antibody
  • duox1 antibody
  • Duox2 antibody
  • LNOX1 antibody
  • LNOX2 antibody
  • NOXEF1 antibody
  • NOXEF2 antibody
  • P138-TOX antibody
  • THOX1 antibody
  • THOX2 antibody
  • Udx1 antibody

Protein level used designations for Dual Oxidase 1 (DUOX1) ELISA Kits

dual oxidase 1 , NADPH thyroid oxidase 1 , flavoprotein NADPH oxidase , large NOX 1 , long NOX 1 , nicotinamide adenine dinucleotide phosphate oxidase , thyroid oxidase 1 , dual oxidase 2

GENE ID SPECIES
588656 Strongylocentrotus purpuratus
100012836 Monodelphis domestica
467673 Pan troglodytes
565097 Danio rerio
5569378 Aedes aegypti
53905 Homo sapiens
99439 Mus musculus
266807 Rattus norvegicus
403720 Canis lupus familiaris
397177 Sus scrofa
510409 Bos taurus
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