anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) Antibodies

DYRK1B is a member of the DYRK family of protein kinases. Additionally we are shipping DYRK1B Proteins (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DYRK1B 9149 Q9Y463
DYRK1B 13549 Q9Z188
DYRK1B 308468  
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Top anti-DYRK1B Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-DYRKB Pab (ABIN391774) in mouse kidney tissue lysate. DYRKB (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of DYRK1B Antibody (Center) in 293 cell line lysates (35ug/lane). This demonstrates the DYRK1B antibody detected the DYRK1B protein (arrow 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of DYRK1B staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of DYRK1B expression in Hela (A), HT1080 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated WB Mouse Dyrk1b Antibody (Center) (ABIN658538) western blot analysis in mouse lung tissue lysates (35 µg/lane). This demonstrates the Dyrk1b antibody detected the Dyrk1b protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 WB Image Sample (50 ug of whole cell lysate) A: mouse liver 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated WB DYRK1B Antibody (Center)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the DYRK1B antibody detected the DYRK1B protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-DYRKB Pab in mouse kidney tissue lysate. DYRKB (Arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  DYRK1B  Sample Type:  Lung Tumor lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Western Blot: Dyrk1B Antibody [NBP1-82643] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: Dyrk1B Antibody [NBP1-82643] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli & vesicles. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details

Top referenced anti-DYRK1B Antibodies

  1. Human Polyclonal DYRK1B Primary Antibody for IHC (p), WB - ABIN391774 : Takahashi-Yanaga, Mori, Matsuzaki, Watanabe, Hirata, Miwa, Morimoto, Sasaguri: Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal DYRK1B Primary Antibody for IHC (p), ELISA - ABIN543895 : Lee, Deng, Friedman: Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells. in Cancer research 2000 (PubMed)
    Show all 3 Pubmed References

More Antibodies against DYRK1B Interaction Partners

Human Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) interaction partners

  1. DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B

  2. DYRK1B mutations associated with metabolic syndrome interfere with the maturation of DYRK1B by tyrosine autophosphorylation and compromise the conformational stability of the catalytic domain, which renders the kinase susceptible to misfolding.

  3. Through the activation of DYRK1B, Hedgehog signaling facilitates microtubule-dependent processes such as intracellular mitochondrial transport, mesenchymal cell polarization or directed cell migration.

  4. Dyrk1B was overexpressed in breast cancer tissues and cells and correlates with FoxO1 phosphorylation and cell proliferation.

  5. High DYRK1B expression is associated with pancreatic and skin cancers.

  6. The study shows that DYRK1B is a novel ERK2 substrate, uncovering new links between two kinases involved in cell fate decisions.

  7. Data reveal a novel role for miR-9 in regulation of the NFAT pathway by targeting KPNB1 and DYRK1B.

  8. NKX3.1 and DYRK1B were shown to interact via the DYRK1B kinase domain. In vitro kinase assay showed that DYRK1B phosphorylated NKX3.1 at serine 185, a residue critical for NKX3.1 steady-state turnover.

  9. Upregulation of Mirk mRNA expression is mediated by CREB binding to two sites in the Mirk promoter upstream of the transcription start site and one site within exon 4.

  10. A founder mutation was identified in DYRK1B, substituting cysteine for arginine at position 102 in 3 families with metabolic syndrome.

  11. DYRK1B is a novel Thr(286)-CCND1 kinase that acts independently of GSK3beta to promote CCND1 degradation.

  12. Mirk/Dyrk1B plays an important role in ovarian cancer cell survival through modulating FoxO translocation.

  13. In line with a redirection of autocrine toward paracrine HH signaling by a KRAS-DYRK1B network, we find high levels of GLI1 expression restricted to the stromal compartment and not to SHH-expressing tumor cells in pancreatic adenocarcinoma.

  14. the kinase Mirk is essential for the growth and survival of osteosarcoma cells.

  15. activation by MKK2 and role as transcriptional activator of HNF1alpha

  16. p38 MAP Kinase suppresses the function of Mirk as a transcriptional activator only when cells are proliferating

  17. Mirk is anti-apoptotic in myoblasts

  18. Mirk is a survival factor for pancreatic ductal adenocarcinoma. Because knockout of Mirk does not cause embryonic lethality, Mirk is not essential for normal cell growth.

  19. This review summarizes the known regulators and functions of Mirk kinase and outlines opportunities for future studies of Mirk in the fields of muscle and tumor biology.

  20. GSK-3beta but also DYRK1B modulates cyclin D1 subcellular localization by the phosphorylation of Thr(288). These results suggest that DIF-3 induces degradation of cyclin D1 through the GSK-3beta- and DYRK1B-mediated threonine phosphorylation in HeLa cells

Mouse (Murine) Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) interaction partners

  1. we demonstrated that Anxa1, Anxa2, and Dyrk1b are upregulated at both the transcriptional and translational levels by the overexpression of GAS1

  2. Through the activation of DYRK1B, Hedgehog signaling facilitates microtubule-dependent processes such as intracellular mitochondrial transport, mesenchymal cell polarization or directed cell migration.

  3. results suggest that functional interactions between BM88/Cend1, RanBPM and Dyrk1B affect the balance between cellular proliferation and differentiation in Neuro 2a cells

  4. Cirp functions to fine-tune the proliferation of undifferentiated spermatogonia by interacting with Dyrk1b.

  5. p38 MAP Kinase suppresses the function of Mirk as a transcriptional activator only when cells are proliferating

  6. dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation

  7. p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase

  8. Mirk may function together with GSK3beta to assist cell arrest by destabilizing cyclin D1.

  9. Mirk is induced within the initial 24 h of myogenic differentiation and enables MEF2 to transcribe the myogenin gene by decreasing the nuclear accumulation of class II HDACs

  10. Mirk is anti-apoptotic in myoblasts

  11. BCL2 and BCL-xL facilitation of G0 quiescence requires BAX, BAK, and p27 phosphorylation by Mirk

DYRK1B Antigen Profile

Protein Summary

DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.

Gene names and symbols associated with DYRK1B

  • dual specificity tyrosine phosphorylation regulated kinase 1B (DYRK1B) antibody
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b) antibody
  • dual specificity tyrosine phosphorylation regulated kinase 1B (Dyrk1b) antibody
  • DYRK1A antibody
  • DYRK1B antibody
  • Mirk antibody

Protein level used designations for DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B , dual specificity tyrosine-phosphorylation-regulated kinase 1B-like , dual specificity tyrosine-phosphorylation-regulated kinase 1B , minibrain-related kinase , mirk protein kinase , dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

GENE ID SPECIES
456030 Pan troglodytes
100012195 Monodelphis domestica
100344122 Oryctolagus cuniculus
100439443 Pongo abelii
100469690 Ailuropoda melanoleuca
9149 Homo sapiens
13549 Mus musculus
308468 Rattus norvegicus
484506 Canis lupus familiaris
100625631 Sus scrofa
507571 Bos taurus
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