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DYRK1B antibody (AA 35-130)

DYRK1B Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN716501
  • Target See all DYRK1B Antibodies
    DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))
    Binding Specificity
    • 15
    • 14
    • 13
    • 10
    • 9
    • 9
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-130
    Reactivity
    • 70
    • 40
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 82
    • 4
    Rabbit
    Clonality
    • 85
    • 1
    Polyclonal
    Conjugate
    • 32
    • 8
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DYRK1B antibody is un-conjugated
    Application
    • 67
    • 51
    • 18
    • 12
    • 12
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MIRK/Dyrk1B
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))
    Alternative Name
    Dyrk1b (DYRK1B Products)
    Synonyms
    DYRK1B antibody, MIRK antibody, Mirk antibody, DYRK1A antibody, dual specificity tyrosine phosphorylation regulated kinase 1B antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b antibody, DYRK1B antibody, Dyrk1b antibody
    Background

    Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).

    Subcellular location: Nucleus

    Synonyms: MIRK, AOMS3, Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Minibrain-related kinase, Mirk protein kinase, DYRK1B

    Gene ID
    9149
    UniProt
    Q9Y463
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