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DTNB encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). Additionally we are shipping Dystrobrevin beta Proteins (8) and Dystrobrevin beta Kits (5) and many more products for this protein.
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Data provide new insights into the role of beta-dystrobrevin in the molecular mechanisms underlying neuronal differentiation that could be relevant in the establishment of the cognitive impairment in Duchene muscular dystrophy.
beta-dystrobrevin interacts with the HMG20 proteins iBRAF and BRAF35
results suggest that dysbindin assembled into BLOC-1 is not a physiological binding partner of the dystrobrevins, likely due to engagement of its dystrobrevin-binding region in interactions with other subunits
Dystrobrevin family gene expression in zebrafish is reported.
a novel function for dystrobrevin as a motor protein receptor that might play a major role in the transport of components of the dystrophin-associated protein complex to specific sites in the cell
kinetics of the dystrobrevin-Kif5A interaction showed a lower affinity of alpha compared to that of beta-dystrobrevin for binding to kinesin
AlphaDB, betaDB, & dystrophin are concentrated at a discrete subset of inhibitory synapses on the somata & dendrites of cerebellar Purkinje cells. Sensorimotor behaviors reflecting cerebellar function are perturbed in mice lacking any of these proteins.
biglycan is important for the maintenance of muscle cell integrity and plays a direct role in regulating the expression and sarcolemmal localization of the intracellular signaling proteins dystrobrevin-1 and -2, alpha- and beta1-syntrophin and nNOS
This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
, dystrobrevin beta
, dystrobrevin, beta
, dystrobrevin, gamma
, dystrobrevin beta-like
, LOW QUALITY PROTEIN: dystrobrevin beta