anti-E2F Transcription Factor 6 (E2F6) Antibodies

E2F6 encodes a member of the E2F transcription factor protein family. Additionally we are shipping E2F6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
E2F6 1876 O75461
E2F6 50496 O54917
E2F6 313978  
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Top anti-E2F6 Antibodies at

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-E2F6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: E2f6 Sample Type: Rat Thymus lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated ChIP, IHC, WB ChIP analysis of Mouse ES cell nuclear lysate, incubated for 16 hours at 4°C. Cross-linking (X-ChIP) using formaldehyde for 10 minutes. Positive control: Tuba3. Negative Control: Beta-Actin. Detection step: Real-time PCR. Immunohistochemical analysis of E2F6 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to E2F6 on HeLa cell (antibody concentration 10 µg/mL). E2F6 monoclonal antibody (M02), clone 1F7-A9. Western Blot analysis of E2F6 expression in HepG2. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, using E2F6 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using E2F6 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ChIP, IF, IHC, IP, WB 100 μL Log in to see 16 Days
Dog Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
Dog Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 7 to 9 Days
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days

E2F6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) ,

Rat (Rattus) ,

Top referenced anti-E2F6 Antibodies

  1. Human Polyclonal E2F6 Primary Antibody for ELISA, WB - ABIN4306784 : McLaughlin-Drubin, Huh, Münger: Human papillomavirus type 16 E7 oncoprotein associates with E2F6. in Journal of virology 2008 (PubMed)

  2. Cow (Bovine) Polyclonal E2F6 Primary Antibody for IHC, WB - ABIN2779510 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against E2F6 Interaction Partners

Human E2F Transcription Factor 6 (E2F6) interaction partners

  1. E2F1 (show E2F1 Antibodies) forms a protein complex with EBNA3C and E2F6, and EBNA3C competes with E2F1 (show E2F1 Antibodies) for E2F6 binding. E2F6 is also recruited by EBNA3C to the E2F1 (show E2F1 Antibodies) promoter, which is critical for EBNA3C-mediated cell proliferation.

  2. miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer.

  3. Analysis data from a panel of cell cycle transcription factors (E2F1, E2F4, E2F6, and GABPA) finds that a set of core cell cycle genes regulated in both U2OS and HeLa cells are bound by multiple cell cycle transcription factors.

  4. After replication stress, the checkpoint kinase (show ATR Antibodies) Chk1 (show CHEK1 Antibodies) phosphorylates E2F6, leading to its dissociation from promoters. This promotes E2F (show E2F1 Antibodies)-dependent transcription, which mediates cell survival by preventing DNA damage and cell death

  5. findings indicate an inhibitory role of E2F6 in the regulation of IL-13 (show IL13 Antibodies) and allergy

  6. E2F6 may recruit BRG1 (show SMARCA4 Antibodies) in transcriptional regulation of genes important for G1/S phase transition of the cell cycle.

  7. data suggest that E2F (show E2F1 Antibodies)- and Myc (show MYC Antibodies)-responsive genes are coregulated by E2F6 complex in quiescent cells

  8. results suggest that E2F6 represses transcription of the brca1, ctip (show RBBP8 Antibodies), art27 (show UXT Antibodies), hp1alpha (show CBX5 Antibodies), and the rbap48 (show RBBP4 Antibodies) genes and depletion of E2F6 resulted in the recruitment of E2F1 (show E2F1 Antibodies) to the target promoters

  9. contains nine exons distributed along 20.4kbp of genomic DNA on chromosome 2 leading to the transcription of six alternatively spliced E2F6 mRNAs that encode four different E2F6 proteins

  10. E2F6 does not contain the domains required for modulation of squamous differentiation

Mouse (Murine) E2F Transcription Factor 6 (E2F6) interaction partners

  1. These data reveal a novel interplay between the E2F pathway, beta2-adrenergic/PKA/PDE4D, and ERK/c-Src axis in fine tuning the pathological hypertrophic growth response.

  2. E2f6 was similarly bound to the proximal promoter regions both in embryonic stem cells (ESCs (show NR2E3 Antibodies)) and epiblast stem cells (EpiSCs)

  3. Data suggest that during development, E2F6 participates in the recruitment of polycomb (show CBX2 Antibodies) proteins to specific target promoters.

  4. The 5' untranslated regions of E2F6 and E2F6b are unusually long, and they contain several upstream AUG codons followed by short reading frames. Our results suggest that translation of E2F6b is initiated by internal ribosome entry.

  5. E2F6 is essential for the long-term somatic silencing of certain male-germ-cell-specific genes, but it is dispensable for cell-cycle regulation.

  6. E2F6 silences SMC1beta (show SMC1B Antibodies) and STAG3 (show STAG3 Antibodies) in somatic cells

  7. This analysis shows that E2f6 and Bmi1 cooperate in the regulation of Hox genes, and consequently axial skeleton development, but not in the repression of the Ink4a-Arf locus.

E2F6 Antigen Profile

Protein Summary

This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms.

Gene names and symbols associated with E2F6

  • E2F transcription factor 6 (E2F6) antibody
  • E2F transcription factor 6 (E2f6) antibody
  • AI462434 antibody
  • E2F-6 antibody
  • E2F6b antibody
  • EMA antibody

Protein level used designations for E2F6

E2F transcription factor 6 , transcription factor E2F6 , E2F-6 , E2F-binding site-modulating activity protein , transcriptional repressor E2F6

100230762 Taeniopygia guttata
100347358 Oryctolagus cuniculus
1876 Homo sapiens
609996 Canis lupus familiaris
514085 Bos taurus
50496 Mus musculus
313978 Rattus norvegicus
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