EGF-Like-Domain, Multiple 7 (EGFL7) ELISA Kits

EGFL7 encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. Additionally we are shipping EGFL7 Antibodies (75) and EGFL7 Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EGFL7 353156 Q9QXT5
EGFL7 51162 Q9UHF1
EGFL7 245963 Q6AZ60
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Top EGFL7 ELISA Kits at

Showing 4 out of 21 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 13.1 pg/mL 31.25 pg/mL - 2000 pg/mL 96 Tests Log in to see 13 to 16 Days
Mouse 0.062 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
Rat 1.56 ng/mL n/a   96 Tests Log in to see 15 to 18 Days
Human 14.8 pg/mL 31.2 pg/mL - 2000 pg/mL   96 Tests Log in to see 15 to 17 Days

Top referenced EGFL7 ELISA Kits

  1. Human EGFL7 ELISA Kit for Sandwich ELISA - ABIN1874436 : Hansen, Andersen, Olsen, Sørensen, Jakobsen: Prognostic importance of circulating epidermal growth factor-like domain 7 in patients with metastatic colorectal cancer treated with chemotherapy and bevacizumab. in Scientific reports 2017 (PubMed)

More ELISA Kits for EGFL7 Interaction Partners

Xenopus laevis EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. we demonstrate for the first time the mechanisms by which lumens are generated within the major vessels in Xenopus and implicate EGFL7 in modulating cell shape and cell-cell junctions to drive proper lumen morphogenesis.

  2. CASZ1/Egfl7/RhoA (show RHOA ELISA Kits) pathway is necessary for promoting endothelial cell behaviors associated with proper vascular assembly.

Zebrafish EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. Under up-regulation of TIE2 (show TEK ELISA Kits)-R849W, egfl7 could be considered a potential reason for venous defects. Moreover, the wnt (show WNT2 ELISA Kits) pathway may perform an important role as a key trigger for head multi-malformations.

  2. These data suggest that Egfl7 provides endothelial cells (EC) with a cue for their extension into the vascular area and in establishing EC cell polarity.

  3. EGFL7 provides a proper microenvironment for endothelial cell migration, thereby enabling accurate patterning.

Mouse (Murine) EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. EGFL7 reduces CNS inflammation in the experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.

  2. Egfl7 is crucial for placental vascularization and embryonic growth.

  3. the angiogenic factor (show VEGFA ELISA Kits) Egfl7 activates the Flt3/Flt3 (show FLT3 ELISA Kits) ligand (show FLT3LG ELISA Kits) pathway and is a key molecular driver enforcing thymus progenitor generation and thereby directly links endothelial cell biology to the production of T cell-based adaptive immunity

  4. EGFL7 is required for VEGF (show VEGFA ELISA Kits) upregulation of the Akt (show AKT1 ELISA Kits)/Erk (1 (show MAPK3 ELISA Kits)/2) pathway during angiogenesis.

  5. EGFL7 enhances EGFR (show EGFR ELISA Kits)-AKT (show AKT1 ELISA Kits) signaling, epithelial-mesenchymal transition, and metastasis of gastric cancer cells.

  6. Egfl7 could be a HIF-1alpha (show HIF1A ELISA Kits) responsive gene regulated by oxygen tension.

  7. Using the BPH (show GLI3 ELISA Kits)/5 model of pre-eclampsia (PE), we show that the downregulation of Egfl7 in compromised placentas occurs prior to the onset of characteristic maternal signs of PE.

  8. egfl7 is initially expressed in all endothelial cells and then is progressively restricted to veins and to their neighbouring capillaries.

  9. EGFL7 is expressed in the bone microenvironment and has a role in promoting endothelial cell migration and tube-like structure formation through integrin-mediated pathways.

  10. Expression of Egfl7 in breast and lung carcinoma cells accelerates tumor growth and metastasis in immunocompetent mice but not in immunodeficient mice.

Human EGF-Like-Domain, Multiple 7 (EGFL7) interaction partners

  1. EGFL7 was found to be a potential predictor for HCC survival and metastasis state.

  2. Levels of both EGFL7 mRNA and EGFL7 protein are increased in blasts of patients with acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)) compared with normal bone marrow cells. High EGFL7 mRNA expression associates with lower complete remission rates, and shorter event-free and overall survival in older (age >/=60 y) and younger (age <60 y) patients with cytogenetically normal AML (show RUNX1 ELISA Kits).

  3. In conclusion, miR (show MLXIP ELISA Kits)-126 could inhibit tumor proliferation and angiogenesis of hepatocellular carcinoma by down-regulating EGFL7 expression

  4. This phase II trial evaluated the efficacy of parsatuzumab (also known as MEGF0444A), a humanized anti-EGFL7 IgG1 monoclonal antibody, in combination with modified FOLFOX6 (mFOLFOX6) (folinic acid, 5-fluorouracil, and oxaliplatin) bevacizumab in patients with previously untreated metastatic colorectal cancer

  5. Oncogenic activation of EGFRwt in GBM is likely maintained by a continuous EGFL7 autocrine flow line.

  6. our results indicated epidermal growth factor-like domain multiple 7 protein participates in growth hormone-secreting pituitary adenoma proliferation and invasion regulation via Notch2/DLL3 signaling pathway. These findings raised the possibility that epidermal growth factor-like domain multiple 7 protein might serve as a useful biomarker to assess growth hormone-secreting pituitary adenoma invasion and prognosis

  7. Egfl7 is thus an endogenous and constitutive repressor of blood vessel endothelial cell activation in normal and inflammatory conditions and participates in a loop of regulation of activation of these cells by pro-inflammatory cytokines.

  8. Up-regulated MALAT1 promoted the invasion and metastasis of GC, and the increase of EGFL7 expression was a potential mechanism via altering its H3 histone (show HIST1H3B ELISA Kits) acetylation level

  9. These findings suggest that the stimulating effect of EGFL7-ESCs on fibroblast proliferation and migration may provide a useful strategy for wound healing.

  10. A gene expression study was conducted to investigate the levels of Egfl7 and miRNA126-5p in human carotid artery atherosclerotic plaques

EGFL7 Antigen Profile

Antigen Summary

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with EGFL7

  • EGF like domain multiple 7 S homeolog (egfl7.S) antibody
  • EGF like domain multiple 7 (EGFL7) antibody
  • EGF-like-domain, multiple 7 (egfl7) antibody
  • EGF like domain multiple 7 (egfl7) antibody
  • EGF-like domain 7 (Egfl7) antibody
  • EGF-like-domain, multiple 7 (Egfl7) antibody
  • EGFL7 antibody
  • MGC53105 antibody
  • MGC147423 antibody
  • NEU1 antibody
  • RP11-251M1.2 antibody
  • VE-STATIN antibody
  • xegfl7 antibody
  • zgc:136669 antibody
  • zgc:152804 antibody
  • ZNEU1 antibody

Protein level used designations for EGFL7

EGF-like-domain, multiple 7 , epidermal growth factor-like protein 7 , rp11-251m1.2 , EGF-like protein 7 , NEU1 protein , NOTCH4-like protein , multiple EGF-like domains protein 7 , multiple epidermal growth factor-like domains protein 7 , vascular endothelial statin , vascular endothelial-statin , EGF-like domain 7 , EGF-like domain-containing protein 7 , Estrogen-regulated protein CBL20 20.4kD , Estrogen-regulated protein CBL20, 20.4kD , multiple EGF-like domain protein 7 , multiple epidermal growth factor-like domain protein 7

379835 Xenopus laevis
417137 Gallus gallus
464868 Pan troglodytes
491250 Canis lupus familiaris
613671 Bos taurus
678640 Danio rerio
780371 Xenopus (Silurana) tropicalis
100226311 Taeniopygia guttata
353156 Mus musculus
51162 Homo sapiens
245963 Rattus norvegicus
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