ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) ELISA Kits

The protein encoded by ELAVL2 is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. Additionally we are shipping ELAVL2 Antibodies (100) and ELAVL2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ELAVL2 1993 Q12926
ELAVL2 15569 Q60899
ELAVL2 286973  
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Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human
  96 Tests 2 to 3 Days
$380.00
Details

More ELISA Kits for ELAVL2 Interaction Partners

Human ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism

  2. The 17 proteins that interact with 10 or more other proteins (P < 0.05, FDR < 0.05) were identified as the hub proteins.

  3. Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 and ELAVL2 among European mothers

  4. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA

  5. increased level of mRNA transcripts detected in Small Cell Lung Cancer patients

Mouse (Murine) ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. we demonstrated HuD downregulation and HuB upregulation in DRG sensory neurons induced by diabetes, which might be correlated with altered post-transcriptional control of RNAs involved in the regulation of thermal hypoalgesia condition caused by the advanced diabetic neuropathy.

  2. ELAVL2 has an ambivalent role in oocytes: it functions as a pleiotropic translational repressor in efficient production of grown oocytes, while its disposal during the NSN/SN transition contributes to the acquisition of full developmental competence.

  3. The predominant expression of REST4, HuB/C/D and nPTB in post-mitotic fiber cells, together with miR-124 expression in vertebrate lenses, was shown.

  4. HuB is expressed in the nucleus of preadipocytes redistributes to the cytosol and to the dense polysomes upon differentiation

  5. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA

Xenopus laevis ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. elrB expression was not detected in Xenopus retina ganglion cell layer until stage 32.

  2. direct correlation between ElrB binding and translational repression by the Vg1 3'-UTR

  3. Data show that, while ElrA and ElrB are 69% identical and both exhibit RNA binding in the nM range, recombinant ElrB, but not ElrA, is able to oligomerise.

  4. Report on the identification of Xenopus ElrA/B proteins and show that Elr-type proteins are part of one RNP complex together with other localization proteins from Xenopus oocytes.

Zebrafish ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) (ELAVL2) interaction partners

  1. that DAZL specifically binds the HuB 3'UTR and protects the message from degradation and/or enhances HuB translation, leading to the germ cell specific expression of HuB protein.

  2. Data show that hub RNA is a target of global miRNA-mediated repression, while the RNA-binding protein Dead end (Dnd) contributes to maintenance of the expression in the primordial germ cells (PGCs).

ELAVL2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with ELAVL2

  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (ELAVL2) antibody
  • ELAV like RNA binding protein 2 (ELAVL2) antibody
  • ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (Elavl2) antibody
  • ELAV like RNA binding protein 2 (Elavl2) antibody
  • ELAV like neuron-specific RNA binding protein 2 L homeolog (elavl2.L) antibody
  • ELAV like neuron-specific RNA binding protein 2 (elavl2) antibody
  • el-1 antibody
  • Elav2 antibody
  • elavl2 antibody
  • elrB antibody
  • hel-n1 antibody
  • heln1 antibody
  • hub antibody
  • mel-N1 antibody
  • p45 antibody
  • Xel-1 antibody
  • zgc:91918 antibody

Protein level used designations for ELAVL2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) , ELAV-like neuronal protein 1 , ELAV-like protein 2 , hu-antigen B , nervous system-specific RNA-binding protein Hel-N1 , ELAV-like 2 , HU-antigen B , nervous system-specific RNA-binding protein Mel-N1 , RNA binding protein HuB , embryonic lethal, abnormal vision-like 2 , Elav like-1 , Protein ElrB

GENE ID SPECIES
100286845 Bos taurus
1993 Homo sapiens
15569 Mus musculus
286973 Rattus norvegicus
100174484 Pongo abelii
394342 Xenopus laevis
100718550 Cavia porcellus
431719 Danio rerio
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