anti-Early Growth Response 2 (EGR2) Antibodies

The protein encoded by EGR2 is a transcription factor with three tandem C2H2-type zinc fingers.

list all antibodies Gene Name GeneID UniProt
Anti-Human EGR2 EGR2 1959 P11161
Anti-Mouse EGR2 EGR2 13654 P08152
Anti-Rat EGR2 EGR2 114090 P51774
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Top anti-EGR2 Antibodies at antibodies-online.com

Showing 10 out of 124 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-EGR2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Lung Human Intestine 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN334389 (0.03µg/ml) staining of HepG2 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Cow Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN461949 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN461949 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Human Adrenal (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN462263 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2 antibody ABIN462263 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$727.83
Details
Human Rabbit Un-conjugated IHC (fro), WB WB Image Western Blot analysis of EGR2 expression in transfected 293T cell line by EGR2 polyclonal antibody. A: Non-transfected lysate. B: EGR2 transfected lysate. 12% SDS PAGE antibody diluted at 1:500 IHC-Fr Image Immunohistochemical analysis of mouse brain tissue (paraformaldehyde-fixed frozen sections), using EGR2, antibody at 1:500 dilution. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, WB Detection of EGR2 in human fetal lung tissue using ABIN258617. Immunocytochemistry/Immunofluorescence: EGR2 Antibody [ABIN2586173] - EGR2 antibody was tested in Hela cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Log in to see 34 Days
$415.44
Details
Human Mouse Un-conjugated IF, WB 100 μL Log in to see 7 to 9 Days
$507.83
Details
Dog Goat Un-conjugated EIA, IHC (p), WB Human Colon (formalin-fixed, paraffin-embedded) stained with EGR2at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with EGR2at 3.75 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 7 to 9 Days
$522.50
Details
Human Rabbit Un-conjugated WB Anti-EGR2 antibody, Western blotting Lane 1: NIH3T3 Cell Lysate Lane 2: MCF-7 Cell Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details

Top referenced anti-EGR2 Antibodies

  1. Cow (Bovine) Polyclonal EGR2 Primary Antibody for IHC, WB - ABIN2792631 : Yoo, Lee: Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal EGR2 Primary Antibody for IHC (p), IHC - ABIN261100 : LeBlanc, Ward, Svaren: Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. in Molecular and cellular biology 2007 (PubMed)

  3. Polyclonal EGR2 Primary Antibody for WB - ABIN540733 : Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal EGR2 Primary Antibody for ICC, IF - ABIN258617 : Hinze, Mayer, Harst, von Kügelgen: Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes. in Journal of molecular and cellular cardiology 2012 (PubMed)

More Antibodies against EGR2 Interaction Partners

Human Early Growth Response 2 (EGR2) interaction partners

  1. Low EGR2 expression is associated with hepatocellular carcinoma.

  2. The study suggests that acetylation of EGR2 is regulated independently of nucleosome remodeling and deacetylase.

  3. Egr2-driven cell surface proteins LAG-3 (show LAG3 Antibodies) and 4-1BB (show TNFRSF9 Antibodies) can identify dysfunctional tumor antigen-specific CD8 (show CD8A Antibodies)(+) TIL (show TLR1 Antibodies).

  4. Egr2 and Egr3 (show EGR3 Antibodies) have emerged as regulatory molecules that suppress excessive immune responses. Mice deficient for Egr2 and Egr3 (show EGR3 Antibodies) develop a lupus-like disease with dysregulated activation of effector T cells. Egr2 and Egr3 (show EGR3 Antibodies) confer suppressive activity to CD4 (show CD4 Antibodies)(+) T cells and regulate the production of inhibitory cytokines such as IL-10 (show IL10 Antibodies) and TGF-beta1 (show TGFB1 Antibodies).

  5. Analysis of consensus EGR (show EGR1 Antibodies)-binding elements (EBEs) showed that the immediate early response 3 (show IER3 Antibodies) gene (IER3 (show IER3 Antibodies)) is a novel transcriptional target gene of EGR2 as confirmed by the luciferase assay, electrophoretic mobility-shift assay (EMSA), chromatin immunoprecipitation (ChIP), and western blot analysis.

  6. In the PPI network, genes may be involved in Down syndrome (DS) by interacting with others, including nuclear receptor subfamily 4 group A member 2 (NR4A2 (show NR4A2 Antibodies))early growth response (EGR)2 and NR4A2EGR3. Therefore, RUNX1 (show RUNX1 Antibodies), NR4A2 (show NR4A2 Antibodies), EGR2, EGR3 (show EGR3 Antibodies) and ID4 (show ID4 Antibodies) may be key genes associated with the pathogenesis of DS.

  7. EGR2 mutation presents as an axonal Charcot-Marie-Tooth phenotype with variable severity.

  8. MicroRNA20a promotes the proliferation and cell cycle of human osteosarcoma cells by suppressing EGR2 expression.

  9. These results suggested that EGR2 overexpression has a pivotal role in the downregulation of cytokines implicated in the pathophysiology of Guillain-Barre syndrome

  10. A recurrent mutation was identified in EGR2 which appears to be associated with the pathogenesis of schizophrenia.

Mouse (Murine) Early Growth Response 2 (EGR2) interaction partners

  1. Egr2 and Egr3 (show EGR3 Antibodies) expressed in T cells cooperatively prevent humoral immune responses by supporting TGF-beta3 (show TGFB3 Antibodies) secretion.

  2. study revealed GCN5 (show KAT2A Antibodies)-mediated EGR2 acetylation as a molecular mechanism that regulates iNKT development.

  3. findings demonstrate a crucial role for Krox20 in arterial valve development and reveal that an excess of neural crest cells may be associated with bicuspid aortic valve.

  4. these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 and YY1 (show YY1 Antibodies) in NIH3T3 cells

  5. Prss56 (show PRSS56 Antibodies) expression was regulated by Egr2 during mouse decidualization.

  6. Egr2 and 3 are upstream regulators of effector CD4 (show CD4 Antibodies) and CD8 (show CD8A Antibodies) T cells that are essential for optimal responses with limited immunopathology.

  7. Egr2 and 3 are antagonists of T-bet function in effector T cells and are important for the control of inflammatory responses of T cells.

  8. We discovered that Tead1 (show TEAD1 Antibodies) and co-activators Yap (show YAP1 Antibodies) and Taz (show TAZ Antibodies) are required for Pmp22 (show PMP22 Antibodies) expression, as well as for the expression of Egr2 Tead1 (show TEAD1 Antibodies) directly binds Pmp22 (show PMP22 Antibodies) and Egr2 enhancers early in development and Tead1 (show TEAD1 Antibodies) binding is induced during myelination, correlating with Pmp22 (show PMP22 Antibodies) expression. The data identify Tead1 (show TEAD1 Antibodies) as a novel regulator of Pmp22 (show PMP22 Antibodies) expression during development in concert with Sox10 (show SOX10 Antibodies) and Egr2

  9. endogenous KLF4 (show KLF4 Antibodies) and Krox20 are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma (show PPARG Antibodies)) is essential.

  10. Decreased expression of Krox20 in mice causes degeneration of the aortic leaflets and disorganization of the extracellular matrix, causing valvular dysfunction.

Zebrafish Early Growth Response 2 (EGR2) interaction partners

  1. A direct, positive autoregulatory loop amplifies and maintains the expression of Krox20, a transcription factor governing vertebrate hindbrain segmentation.

  2. Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4.

  3. Data show that Irx7 and Irx1b are required for the proper formation and specification of rhombomeres 1 to 4, and that Irx7 functionally interacts with Meis1.1 (show MEIS1 Antibodies) to activate the expression of anterior hindbrain markers, such as krox20.

EGR2 Antigen Profile

Protein Summary

The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with EGR2

  • early growth response 2 (EGR2) antibody
  • early growth response 2 (Egr2) antibody
  • early growth response 2b (egr2b) antibody
  • AT591 antibody
  • cb427 antibody
  • CMT1D antibody
  • CMT4E antibody
  • Egr-2 antibody
  • egr2 antibody
  • id:ibd5073 antibody
  • Krox-20 antibody
  • krox20 antibody
  • KRX-20 antibody
  • krx20 antibody
  • NGF1-B antibody
  • wu:fb71h10 antibody
  • Zfp-6 antibody
  • Zfp-25 antibody
  • zgc:92210 antibody

Protein level used designations for EGR2

E3 SUMO-protein ligase EGR2 , KROX-20, Drosophila, homolog (early growth response-2) , early growth response protein 2 , zinc finger protein Krox-20 , early growth response 2 (Krox-20 homolog, Drosophila) , EGR-2 , EGR-2b , early growth response protein 2b , krox-20 , protein krx-20

GENE ID SPECIES
1959 Homo sapiens
479219 Canis lupus familiaris
100038004 Sus scrofa
13654 Mus musculus
114090 Rattus norvegicus
100721167 Cavia porcellus
100297981 Bos taurus
101122407 Ovis aries
30190 Danio rerio
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