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EGR2 antibody (C-Term)

EGR2 Reactivity: Human, Mouse, Rat, Pig, Dog, Horse, Cow, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2792631
  • Target See all EGR2 Antibodies
    EGR2 (Early Growth Response 2 (EGR2))
    Binding Specificity
    • 15
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 61
    • 42
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Pig, Dog, Horse, Cow, Rabbit
    Host
    • 59
    • 5
    • 1
    Rabbit
    Clonality
    • 52
    • 13
    Polyclonal
    Conjugate
    • 32
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This EGR2 antibody is un-conjugated
    Application
    • 48
    • 20
    • 13
    • 13
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    PFACDYCGRK FARSDERKRH TKIHLRQKER KSSAPSASVP APSTASCSGG
    Cross-Reactivity
    Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
    Predicted Reactivity
    Cow: 100%, Dog: 92%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 92%, Rat: 92%
    Characteristics
    This is a rabbit polyclonal antibody against EGR2. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human EGR2
    Top Product
    Discover our top product EGR2 Primary Antibody
  • Application Notes
    WB Suggested Anti-EGR2 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:312500
    Positive Control: Human Lung.
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 476 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Damm, Mylonas, Cosson, Yoshida, Della Valle, Mouly, Diop, Scourzic, Shiraishi, Chiba, Tanaka, Miyano, Kikushige, Davi, Lambert, Gautheret, Merle-Béral, Sutton, Dessen, Solary, Akashi, Vainchenker et al.: "Acquired initiating mutations in early hematopoietic cells of CLL patients. ..." in: Cancer discovery, Vol. 4, Issue 9, pp. 1088-101, (2014) (PubMed).

    Lagrange, Martin, Droin, Aucagne, Paggetti, Largeot, Itzykson, Solary, Delva, Bastie: "A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages." in: Biochimica et biophysica acta, Vol. 1833, Issue 8, pp. 1936-46, (2013) (PubMed).

    Latasa, Ituero, Moran-Gonzalez, Aranda, Cosgaya: "Retinoic acid regulates myelin formation in the peripheral nervous system." in: Glia, Vol. 58, Issue 12, pp. 1451-64, (2010) (PubMed).

  • Target
    EGR2 (Early Growth Response 2 (EGR2))
    Alternative Name
    EGR2 (EGR2 Products)
    Synonyms
    AT591 antibody, CMT1D antibody, CMT4E antibody, KROX20 antibody, Egr-2 antibody, Krox-20 antibody, Krox20 antibody, NGF1-B antibody, Zfp-25 antibody, Zfp-6 antibody, KRX-20 antibody, cb427 antibody, egr2 antibody, id:ibd5073 antibody, krox20 antibody, krx20 antibody, wu:fb71h10 antibody, zgc:92210 antibody, frb35 antibody, early growth response 2 antibody, early growth response 2b antibody, early growth response 2a antibody, EGR2 antibody, Egr2 antibody, egr2b antibody, egr2a antibody
    Background
    The early growth response protein 2 (EGR2) is a transcription factor with three tandem C2H2-type zinc fingers. Mutations in this gene are associated with the autosomal dominant Charcot-Marie-Tooth disease, type 1.The early growth response protein 2 is a transcription factor with three tandem C2H2-type zinc fingers. Mutations in this gene are associated with the autosomal dominant Charcot-Marie-Tooth disease, type 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CMT1D, CMT4E, DKFZp686J1957, FLJ14547, KROX20, AT591
    Protein Interaction Partner: RPL7L1, HN1L, RIMKLB, RBM15B, NDUFS2, BPGM, SRA1, DTX1, WWP2, UBC, UBE2I, NAB2, SOX8, MED31, SOX10, HCFC1, ACP5, NFATC1, FASLG,
    Protein Size: 476
    Molecular Weight
    50 kDa
    Gene ID
    1959
    NCBI Accession
    NM_000399, NP_000390
    UniProt
    P11161
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