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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Additionally we are shipping Elastase, Neutrophil Expressed Kits (106) and Elastase, Neutrophil Expressed Proteins (15) and many more products for this protein.
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Dog (Canine) Polyclonal ELANE Primary Antibody for FACS, IF (p) - ABIN1386058
Jeffery, Kimura, Gray, Lueth, Bellaire, LeVine: Dogs cast NETs too: Canine neutrophil extracellular traps in health and immune-mediated hemolytic anemia. in Veterinary immunology and immunopathology 2015
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Human Polyclonal ELANE Primary Antibody for IA - ABIN2192191
Dentener, Francot, Hiemstra, Tool, Verhoeven, Vandenabeele, Buurman: Bactericidal/permeability-increasing protein release in whole blood ex vivo: strong induction by lipopolysaccharide and tumor necrosis factor-alpha. in The Journal of infectious diseases 1997
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Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.
, bone marrow serine protease
, elastase 2, neutrophil
, granulocyte-derived elastase
, human leukocyte elastase
, leukocyte elastase
, neutrophil elastase
, polymorphonuclear elastase
, serine protease
, elastase, neutrophil expressed
, LOW QUALITY PROTEIN: neutrophil elastase