anti-Elastase, Neutrophil Expressed Antibodies

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin.

Data Quality
  • 2
  • 26
Type
  • 142
    Primary antibodies
Antigen
  • 142
Reactivity
  • 122
  • 26
  • 23
  • 20
  • 1
Application
  • 79
  • 62
  • 25
  • 18
  • 16
Detection Method
  • 3
Host
  • 82
  • 47
  • 9
  • 4
Clonality
  • 89
  • 53
Clone
  • 3
  • 3
  • 3
  • 3
  • 2
Binding Specificity
  • 15
  • 15
  • 12
  • 8
  • 8
Conjugate
  • 90
  • 8
  • 6
  • 5
  • 4
Isotype
  • 61
  • 12
  • 11
  • 4
  • 3
Format
  • 93
  • 9
Suggested next Filters
142 Products
ReactivityHuman, Monkey
Application ELISA, FACS, IHC, WB
Order details Cat. No. ABIN5611333
$430.10
0.1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityHuman, Rat (Rattus)
Application ELISA, FACS, WB
Order details Cat. No. ABIN5611332
$430.10
0.1 mg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days
ReactivityMouse (Murine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN4886568
$280.00
100 μg
Plus shipping costs $45.00
Delivery in 4 to 6 Business Days
ReactivityDog (Canine), Human, Mouse (Murine), Rat (Rattus)
Application FACS, IF (p), IHC (p), WB
Order details Cat. No. ABIN1386058
$339.90
100 μL
Plus shipping costs $45.00
Delivery in 3 to 7 Business Days
ReactivityHuman
Application IA
Order details Cat. No. ABIN2192191
Pubmed
$716.45
100 μg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application IF, ELISA, WB
Order details Cat. No. ABIN1327510
$364.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityMouse (Murine), Rat (Rattus)
Application IHC (p), WB
Order details Cat. No. ABIN5647773
$452.38
100 μg
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN3030798
$452.38
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application RIA, ELISA, WB
Order details Cat. No. ABIN109822
$304.92
Plus shipping costs $45.00
Delivery in 5 to 6 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6140110
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityHuman
Application IA, WB
Order details Cat. No. ABIN2192035
$648.22
100 μg
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN1858706
$221.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityMouse (Murine)
Application ICC, IHC (fro), IHC (p), ELISA, WB
Order details Cat. No. ABIN1867729
$226.00
100 μL
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN560723
$238.67
50 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Mouse (Murine)
Application WB
Order details Cat. No. ABIN6292897
$309.73
50 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
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Elastase, Neutrophil Expressed (ELANE) Antigen Profile

Protein Summary

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.

Gene names and symbols associated with ELANE

  • elastase, neutrophil expressed (ELANE) antibody
  • elastase, neutrophil expressed (Elane) antibody
  • proteinase 3 (prtn3) antibody
  • ela2 antibody
  • ELANE antibody
  • F430011M15Rik antibody
  • GE antibody
  • HLE antibody
  • HNE antibody
  • NE antibody
  • PMN-E antibody
  • SCN1 antibody

Protein level used designations for ELANE

PMN elastase , bone marrow serine protease , elastase 2, neutrophil , elastase-2 , granulocyte-derived elastase , human leukocyte elastase , leukocyte elastase , medullasin , neutrophil elastase , polymorphonuclear elastase , serine protease , elastase, neutrophil expressed , LOW QUALITY PROTEIN: neutrophil elastase

GENE ID SPECIES
1991 Homo sapiens
50701 Mus musculus
299606 Rattus norvegicus
442980 Canis lupus familiaris
448597 Xenopus (Silurana) tropicalis
721134 Macaca mulatta
749897 Pan troglodytes
100126050 Bos taurus
100301482 Felis catus
100724414 Cavia porcellus
100522182 Sus scrofa
102173292 Capra hircus
101110841 Ovis aries musimon
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