anti-Empty Spiracles Homeobox 2 (EMX2) Antibodies

EMX2 encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Additionally we are shipping EMX2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EMX2 2018 Q04743
EMX2 13797 Q04744
EMX2 499380  
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Top anti-EMX2 Antibodies at

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-EMX2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate Rabbit Anti-EMX2 Antibody  Paraffin Embedded Tissue: Human Muscle Cellular Data: Skeletal muscle cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EMX2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, IHC (p) Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.05 mg Log in to see 11 to 14 Days
Human Rabbit Un-conjugated FACS, WB EMX2 Antibody (Center) (ABIN651733) western blot analysis in HL-60 cell line lysates (15 µg/lane). This demonstrates the EMX2 antibody detected the EMX2 protein (arrow). EMX2 Antibody (Center) (ABIN651733) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of EMX2 using K562 whole cell lysates 100 μL Log in to see 11 to 12 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: EMX2 Antibody [NBP2-39052] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: RT-4 Immunohistochemistry: EMX2 Antibody [NBP2-39052] - Staining of human uterus shows moderate nuclear positivity in uterus. 0.1 mL Log in to see 10 to 13 Days
Human Mouse Un-conjugated ELISA, IHC, IHC (p) Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skeletal muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 11 to 14 Days
Human Rabbit Un-conjugated EIA, IHC (p)   0.1 mg Log in to see 4 to 8 Days
Human Rabbit Un-conjugated IHC (p) Formalin-Fixed, Paraffin-Embedded Human Brain, Cortex stained with EMX2 antibody at 5 µg/ml after heat-induced antigen retrieval. Formalin-Fixed, Paraffin-Embedded Human Prostate: stained with EMX2 antibody at 5 µg/ml after heat-induced antigen retrieval. 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, IHC, WB Immunohistochemical analysis of EMX2 in human lung tissue with EMX2 polyclonal antibody  at 2.5 ug/mL. Western blot analysis of EMX2 in human lung tissue with EMX2 polyclonal antibody  at (lane 1) 1 and (lane 2) 2 ug/mL. 100 μg Log in to see 11 to 12 Days

Top referenced anti-EMX2 Antibodies

  1. Human Monoclonal EMX2 Primary Antibody for IHC (p), ELISA - ABIN515282 : Falcone, Filippis, Granzotto, Mallamaci: Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. in Glia 2015 (PubMed)

More Antibodies against EMX2 Interaction Partners

Human Empty Spiracles Homeobox 2 (EMX2) interaction partners

  1. In the three variants of papillary thyroid cancer (PTC), EMX2 was significantly downregulated in classical PTC, while EMX2OS was significantly downregulated in follicular and classical PTC, compared with adjacent normal tissues. Kaplan-Meier survival curves showed that EMX2 and EMX2OS expression was not related to relapse-free survival in follicular PTC.

  2. EMX2 is frequently down-regulated in human colorectal cancer, and down-regulation of EMX2 is a prognostic marker for disease-free and overall survival.

  3. Emx2 is a novel promising tool for therapy of glioblastoma and prevention of its recurrences.

  4. EMX2 inhibits proliferation and tumorigenesis through inactivation of the Wnt/beta-catenin pathway in CRC cells.

  5. EMX2 expression was down-regulated in lung SCC tissue compared to matched adjacent normal tissue. EMX2 expression was associated with improved overall survival. Knockdown promoted chemo-resistance and cell migration.

  6. Although it is uncommon (0.19%), EMX2 is the first gene identified that if perturbed may cause isolated incomplete mullerian fusion.

  7. Deletions of EMX2 have been associated with a wide range of DSD.

  8. EMX2 expression is downregulated in advanced cases of malignant pleural mesothelioma and may serve as an important prognostic and predictive molecular biomarker of progression-free survival.

  9. downregulation of empty spiracles homeobox 2 (EMX2) was associated with tumor progression and may be a critical factor in the carcinogenesis and progression of endometrial cancer

  10. EMX2 expression led to inhibition of cell proliferation and Wnt signaling pathway both in vitro and in a gastric cancer xenograft model in vivo.

  11. Study analyzed mutations of EMX2 gene in 45 prostate carcinomas, 51 non-small cell lung cancers, 43 gastric carcinomas, 44 colorectal carcinomas, and 43 breast carcinomas by polymerase chain reaction and single-strand conformation polymorphism assay.

  12. Downregulation of EMX2 is associated with clinical outcomes in lung adenocarcinoma.

  13. Data show that human teneurin-1 is directly regulated by EMX2 at a conserved promoter region upstream of the transcription start site, and identify and characterize the EMX2 dependent promoter element of human teneurin-1.

  14. promoter. Restoration of EMX2 expression in lung cancer cells lacking endogenous EMX2 expression suppressed cell proliferation and invasive phenotypes

  15. EMX2 gene has been reported in schezencephaly (cleft brain) including epilepsy in some patients.

  16. In these studies we identify and characterize the regulation of EMX2 by HOXA10.

  17. Endometrial EMX2 expression is aberrant in women with endometriosis and is mediated by altered HOXA10 expression.

  18. EMX2 levels in cortical progenitors of EMX2 transgenic mice disproportionately specify sizes and positions of primary cortical areas.

  19. It is unlikely that the EMX2 or PTEN gene variants investigated contribute to risk for initiation and/or development of endometriosis.

  20. provide results of EMX2 sequencing in 39 new schizencephaly patients, detecting no pathogenic mutations

Mouse (Murine) Empty Spiracles Homeobox 2 (EMX2) interaction partners

  1. This initial screen isolated two potential Emx2-binding partner proteins, Cnot6l and QkI-7. These novel Emx2-binding proteins are involved in multiple levels of mRNA metabolism that including splicing, mRNA export, translation, and destruction

  2. We found that expression of Emx2 and Lhx2 initiated between neuronal progenitor and neuronal precursor stages. As far as the sensory neurons of the vomeronasal organ are concerned, Meis1 and Meis2 were only expressed in the apical layer, together with Gnai2, but not in the basal layer.

  3. Results showed that Emx2 overexpression in cortico-cerebral stem cells inhibits astrogenesis, largely in a cell-autonomous way

  4. Emx2 expression led to inhibition of cell proliferation and Wnt signaling pathway both in vitro and in a gastric cancer xenograft model in vivo.

  5. A high incidence of urinary tract anomalies in Pax2;Emx2 were found in compound heterozygous mice that are not found in single heterozygous mice.

  6. Pbx genes share overlapping functions and Pbx1 and Emx2 genetically interact in pelvic formation.

  7. These results strongly suggest that Emx2 is required for regulation of tight junction assembly and allowing migration of the gonadal epithelia to the mesenchyme, which are possibly mediated by suppression of Egfr expression.

  8. detailed picture of Emx2 and Foxg1 activities in cortico-cerebral histogenesis resulted from this study

  9. Emx2 expression was greatly reduced, but persisted in the telencephalon of the enhancer mutant, indicating that there exists another enhancer for Emx2 expression unique to mammalian telencephalon.

  10. Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1

  11. Emx2 and early hair cell development in the mouse inner ear are reported.

  12. activation of Emx2 by a short antisense transcript may be a prototype of a method for overexpressing single specific genes, without introducing additional copies of them into the genome

  13. Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system.

  14. Emx2 is a direct transcriptional target of Wnt and Bmp signalling and provide insights into a genetic hierarchy involving Gli3, Emx2 and Bmp and Wnt genes in the control of dorsal telencephalic development.

  15. Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double knockout mice

  16. High expression of one functional allele of either of the homeobox genes Emx2 or Pax6 in the dorsal telencephalon is necessary and sufficient to activate morphogenesis of cerebral cortex

  17. early targeting abnormality is associated with Emx2 altered expression pattern in the cortex

  18. Emx2 is essential for the terminal differentiation of granular cells and the correct formation of extrinsic and intrinsic hippocampal connections

  19. By using Northern analysis and in situ hybridization, we found that EMX2 is expressed in the adult urogenital tract in an inverse temporal pattern from HOXA10, suggestive of a negative regulatory relationship.

  20. The more severe phenotypes in Emx double mutants suggest that Emx1 and Emx2 cooperate to regulate multiple features of cortical development.

EMX2 Antigen Profile

Protein Summary

This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Gene names and symbols associated with EMX2

  • empty spiracles homeobox 2 (EMX2) antibody
  • empty spiracles homeobox 2 (Emx2) antibody
  • Pdo antibody
  • RGD1564797 antibody

Protein level used designations for EMX2

empty spiracles homolog 2 , empty spiracles-like protein 2 , homeobox protein EMX2

2018 Homo sapiens
13797 Mus musculus
523601 Bos taurus
423923 Gallus gallus
610697 Canis lupus familiaris
499380 Rattus norvegicus
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