Endoglin Proteins (ENG)

ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Additionally we are shipping Endoglin Antibodies (797) and Endoglin Kits (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENG 2022 P17813
ENG 13805 Q63961
ENG 497010  
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Top Endoglin Proteins at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
Human Cells Human Fc Tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
$547.80
Details
Human Cells Human His tag 50 μg Log in to see 20 to 21 Days
$382.80
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Insect cells (Sf9) Mouse His tag   100 μg Log in to see 2 to 3 Days
$1,149.50
Details
Escherichia coli (E. coli) Human His tag,TRX tag   50 μg Log in to see 4 Days
$385.00
Details
Escherichia coli (E. coli) Human TRX tag,His tag   10 μg Log in to see 15 to 16 Days
$225.00
Details

ENG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , , , , ,
Mouse (Murine) , , , ,
,
Rat (Rattus)

Top referenced Endoglin Proteins

  1. Human ENG Protein expressed in Wheat germ - ABIN1352793 : Banerjee, Dhara, Bacanamwo: Endoglin is a novel endothelial cell specification gene. in Stem cell research 2011 (PubMed)

More Proteins for Endoglin (ENG) Interaction Partners

Human Endoglin (ENG) interaction partners

  1. Dendritic-cells loaded with lysates derived from CD105+ human renal cell carcinoma (show MOK Proteins) cancer stem cells (CSCs) induced more functionally specific active T cells and specific antibodies against CSCs, and clearly depressed the tumor growth in mice.

  2. Report no relationship between serum endoglin levels and ovarian cancer microvessel density and tumor endoglin expression.

  3. TGF-beta (show TGFB1 Proteins) type I, II, and III receptors were all identified in pregnant serum; all were substantially elevated in early-onset but not late-onset PE. Endoglin was increased in both subtypes.

  4. Study described present a series of pulmonary arterial hypertension patients with mutations in the ENG gene, some of them not previously described, exhibiting clinical and hemodynamic alterations. These results suggest the presence of these mutations may be associated with the severity of the disease.

  5. Several germline variants in Hamartomatous Polyposis Syndrome genes were detected, among them three in ENG, two in BMPR1A (show BMPR1A Proteins), one in PTEN, and one in SMAD4 (show SMAD4 Proteins). Although some of the detected variants have been reported previously none could be definitely pathogenic or likely pathogenic.

  6. 9q33.3q34.11 microdeletion including ENG gene identified in four patients with intellectual disability, epilepsy, nail (show CD244 Proteins) dysplasia and bone malformations.

  7. Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.

  8. Soluble endoglin did not vary over the pregnancy course or between gestational hypertension, preeclampsia, and control groups.

  9. Serum and placental LXR-alpha (show NR1H3 Proteins) and endoglin levels were significantly higher in patients with preeclampsia than those in control group (P<0.05, each).

  10. Our findings suggest a stronger chondrogenic potential of CD105(+) SMSCs in comparison to that of CD105(-) SMSCs and that CD105 enhances chondrogenesis of SMSCs by regulating TGF-beta (show TGFB1 Proteins)/Smad2 (show SMAD2 Proteins) signaling pathway, but not Smad1 (show GARS Proteins)/5. Our study provides a better understanding of CD105 with respect to chondrogenic differentiation.

Mouse (Murine) Endoglin (ENG) interaction partners

  1. Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.

  2. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 (show KDR Proteins) signalling.

  3. Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

  4. Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.

  5. the TGFbeta1 (show TGFB1 Proteins) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload

  6. Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.

  7. Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.

  8. The changes in CD90 (show THY1 Proteins) and CD105 expression in the testis and ovary of mice are reported.

  9. the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patients.

  10. These results demonstrate a requirement for endoglin in descendants of Pax3 (show PAX3 Proteins)-expressing vascular cell precursors.

Endoglin (ENG) Protein Profile

Protein Summary

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Endoglin Proteins (ENG)

  • endoglin (ENG)
  • endoglin (Eng)
  • AI528660 protein
  • AI662476 protein
  • CD105 protein
  • DKFZp469D0419 protein
  • END protein
  • ENG protein
  • HHT1 protein
  • MGC137842 protein
  • ORW1 protein
  • S-endoglin protein

Protein level used designations for Endoglin Proteins (ENG)

endoglin (Osler-Rendu-Weber syndrome 1) , endoglin , endoglin-like , CD105 antigen , cell surface MJ7/18 antigen , transmembrane glycoprotein

GENE ID SPECIES
609166 Canis lupus familiaris
615844 Bos taurus
741046 Pan troglodytes
771557 Gallus gallus
100173392 Pongo abelii
100226246 Taeniopygia guttata
100357448 Oryctolagus cuniculus
100387791 Callithrix jacchus
397096 Sus scrofa
2022 Homo sapiens
13805 Mus musculus
497010 Rattus norvegicus
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