anti-Engrailed Homeobox 2 (EN2) Antibodies

Homeobox-containing genes are thought to have a role in controlling development. Additionally we are shipping EN2 Kits (14) and EN2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EN2 13799 P09066
EN2 2020 P19622
EN2 499964  
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Top anti-EN2 Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-EN2 Antibody Titration: 0.05ug/mlELISA Titer: 1:2500Positive Control: Human cerebellum Host:  Rabbit  Target Name:  EN2  Sample Tissue:  Human Jurkat  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$319.00
Details
Mouse Goat Un-conjugated ELISA, WB EB07120 (0.1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$429.62
Details
Guinea Pig Rabbit Un-conjugated IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with EN2 antibody ABIN462164 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-EN2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms ... 50 μg Log in to see 11 to 14 Days
$727.83
Details
Hamster Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of EN2 antibody (C-term) (ABIN391665) in 293 cell line lysates and mouse stomach and lung tissue lysates (35 µg/lane). EN2 (arrow) was detected using the purified polyclonal antibody. Anti-EN2Antibody(C-term)at 1:1000 dilution + Neuro-2a whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 34 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:1000 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of EN2 antibody (C-term-2) (ABIN391666) in NCI-H460 cell line lysates (35 µg/lane). EN2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain with EN2 Antibody (C-term-2), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of EN2 Antibody (C-term) (ABIN652344) in mouse cerebellum, brain tissue lysates (35 µg/lane). EN2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with EN2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated EIA, WB   0.4 mL Log in to see 8 to 11 Days
$517.00
Details
Rat Goat Un-conjugated ELISA, WB ABIN251271 (0.5?g/ml) staining of Mouse Brain lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: engrailed homeobox 2 Antibody [ABIN251271] - (0.1ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated IP, WB Western Blot: EN2 Antibody [NBP2-14947] - Sample (30 ug of whole cell lysate) A: MCF-7 12% SDS PAGE; antibody diluted at 1:10000. Immunoprecipitation: engrailed homeobox 2 Antibody  - HeLa whole cell lysate/extract A. 40 ug HeLa whole cell lysate/extract B. Control with 2 ug of preimmune rabbit IgG C. Immunoprecipitation of EN2 protein by 2 ug of EN2 antibody 12% SDS-PAGE The immunoprecipitated EN2 protein was detected by EN2 antibody diluted at 1:1000. EasyBlot anti-rabbit IgG was used as a secondary reagent. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details

Top referenced anti-EN2 Antibodies

  1. Human Polyclonal EN2 Primary Antibody for IHC (p), WB - ABIN1391947 : De Paoli, Gogalic, Sauer, Preininger, Pandha, Simpson, Horvath, Marquette: Multiplatform Biomarker Discovery for Bladder Cancer Recurrence Diagnosis. in Disease markers 2016 (PubMed)

  2. Rat (Rattus) Polyclonal EN2 Primary Antibody for ELISA, WB - ABIN251271 : Benayed, Gharani, Rossman, Mancuso, Lazar, Kamdar, Bruse, Tischfield, Smith, Zimmerman, Dicicco-Bloom, Brzustowicz, Millonig: Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus. in American journal of human genetics 2005 (PubMed)

  3. Dog (Canine) Polyclonal EN2 Primary Antibody for IHC, WB - ABIN2777264 : Zhong, Serajee, Nabi, Huq: No association between the EN2 gene and autistic disorder. in Journal of medical genetics 2003 (PubMed)

More Antibodies against EN2 Interaction Partners

Mouse (Murine) Engrailed Homeobox 2 (EN2) interaction partners

  1. This study demonstrated that Ketogenic diet exposure during the juvenile period increases social behaviors and forebrain neural activation in adult Engrailed 2 null mice.

  2. Study showed that BDNF (show BDNF Antibodies) signaling through its low-affinity receptor p75 (show NGFR Antibodies) is compromised in the forebrain of En2-/- mice; BDNF (show BDNF Antibodies) signaling deficits might be involved in the neurodevelopmental alterations observed in the En2-/- forebrain

  3. En2 deletion reduces monoamine innervation of target forebrain structures, affecting forebrain structural growth, postnatal neurogenesis and related behavior.

  4. confirm the early neurotransmitter deficit with a late compensatory recovery in En2 KO-mice further suggesting that this experimental animal may be considered a good predictive model for the human disease

  5. The homeoprotein Engrailed is not only a survival factor for mesencephalic dopaminergic (mDA) neurons during development, but continues to exert neuroprotective and physiological functions in adult mDA neurons. [Review]

  6. En2-/- hippocampus, neurofibromin (show NF1 Antibodies)-dependent pathways converging on SynI (show SYN1 Antibodies) phosphorylation might underlie hippocampal-dependent learning deficits observed in En2-/- mice.

  7. This study demonistrated that engrailed 2 knock-out mice show impaired spatial learning with hippocampal dysreulation.

  8. EN2 levels are increased in affected individuals with an A-C/G-T genotype, supporting EN2 as an autism spectrum disorder susceptibility gene.

  9. This study showed that the Engrailed proteins are present in postnatal GABAergic neurons of the mouse hippocampus and cerebral cortex, and adult En2(-/-) mice show reduced expression of GABAergic marker mRNAs in these areas.

  10. En1 (show EN1 Antibodies) is the predominant functional En paralog in maturing 5-HT (show DDC Antibodies) neurons, although a small contribution from En2 was reproducibly detected

Human Engrailed Homeobox 2 (EN2) interaction partners

  1. we confirmed that engrailed-2 is the target of hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-27b in human cytomegalovirus-infected glioma cells

  2. The critical role of miR212 in inhibiting prostate tumor growth was verified in xenograft models of prostate cancer. These findings highlighted the role of miR212 in PCa (show FLVCR1 Antibodies) progression. More importantly, we speculate that EN-2 is a direct target gene of miR212.

  3. We identified a novel heterozygous missense variant (c.425C>G, p.Pro142Arg) in the Engrailed 2 (EN2) gene in two patients. The G variant has never been reported in public databases and was absent in 100 Thai patients with ASD (show ARSD Antibodies) and 435 Thai controls. A case-control study showed that the G allele of c.425C>G was significantly associated with ASD (show ARSD Antibodies)

  4. EN2 is negatively regulated by miR (show MLXIP Antibodies)-605, and down-regulation of miR (show MLXIP Antibodies)-605 promotes the proliferation and invasion of prostate cancer (PCa (show FLVCR1 Antibodies)) cells by up-regulating EN2, which leads to PCa (show FLVCR1 Antibodies) development and progression

  5. Our data suggest that the functional interaction of miR (show MLXIP Antibodies)-33a and EN-2 is involved in tumorigenesis of prostate cancer

  6. the results demonstrated that EN2 might play an anti-oncogenic role in oncogenesis and development of CCRCC, thereby maintaining the normal growth of human renal tubular epithelial cells.

  7. EN2 may be a candidate oncogene in bladder cancer by activating the PI3K/Akt pathway and inhibiting PTEN.

  8. Engrailed-2 (EN-2) is a developmentally regulated homeobox (show Lbx1 Antibodies) gene that is essential for Purkinje cell maturation and normal cerebellar development and patterning.

  9. The mean EN2 levels in prostate cancer patients were 3.76-fold higher than those in non-prostate patients after prostate massage.

  10. The exact role of EN2 expression in renal carcinoma (show TSC2 Antibodies) carcinogenesis requires further investigation.

EN2 Antigen Profile

Protein Summary

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Gene names and symbols associated with EN2

  • engrailed homeobox 2 (EN2) antibody
  • engrailed homeobox (en) antibody
  • engrailed 2 (En2) antibody
  • engrailed homeobox 2 (En2) antibody
  • BB131122 antibody
  • en antibody
  • En-2 antibody
  • en2 antibody
  • Gg-En-2 antibody
  • RGD1561842 antibody

Protein level used designations for EN2

engrailed homeobox 2 , engrailed 2 , engrailed homolog 2 , engrailed homeobox , homeobox protein en-2 , homeobox protein engrailed-2 , mo-En-2 , engrailed-2 , hu-En-2

GENE ID SPECIES
280783 Bos taurus
716307 Macaca mulatta
742707 Pan troglodytes
100303466 Saccoglossus kowalevskii
13799 Mus musculus
2020 Homo sapiens
499964 Rattus norvegicus
100859435 Gallus gallus
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