Eosinophil Cationic Protein Proteins (ECP)

Cytotoxin and helminthotoxin with ribonuclease activity.

list all proteins Gene Name GeneID UniProt
Rat ECP ECP 192264 P70709
Mouse ECP ECP 13587 P97425
Human ECP ECP 6037 P12724
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Top Eosinophil Cationic Protein Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$656.00
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Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$701.00
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Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$749.00
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Escherichia coli (E. coli) General His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$560.00
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Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$400.00
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,267.83
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Yeast Macaca nemestrina His tag   1 mg Log in to see 60 to 71 Days
$2,277.00
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Yeast Arabidopsis thaliana His tag   1 mg Log in to see 60 to 71 Days
$2,495.17
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HEK-293 Cells Human His tag   10 μg Log in to see 8 to 11 Days
$297.00
Details

More Proteins for Eosinophil Cationic Protein (ECP) Interaction Partners

Mouse (Murine) Eosinophil Cationic Protein (ECP) interaction partners

  1. Testing spatial memory and hippocampal long-term potentiation revealed an impairment in APP (show APP Proteins)/PS1 (show PSEN1 Proteins) Ear2 (show NR2F6 Proteins)(-/-) mice, whereas APP (show APP Proteins)/PS1 (show PSEN1 Proteins) or Ear2 (show NR2F6 Proteins)(-/-) mice showed only minor changes.

  2. this suggests that ECP can activate a canonical Wnt/b-catenin signaling pathway by enhancing the stabilization of b-catenin during cardiomyocyte differentiation.

  3. Ear2 (show NR2F6 Proteins) ligand binding domain is required for Rasd1 (show RASD1 Proteins) to alleviate Ear2 (show NR2F6 Proteins)-mediated repression of renin (show REN Proteins) transcription.

  4. was selectively chemotactic for dendritic cells; induced the activation of p42 (show EPB42 Proteins)/44 MAPK (show MAPK1 Proteins) in DCs

  5. decreased expression of total mEar2 mRNA and protein in lung tissue and a corresponding fivefold drop in ribonuclease activity in BALF in pneumovirus infection of mice

  6. EDN can activate myeloid DCs by triggering the Toll-like receptor (TLR)2-myeloid differentiation factor 88 signaling pathway

Human Eosinophil Cationic Protein (ECP) interaction partners

  1. measuring serum ECP levels is helpful for assessing the efficacy of inhaled corticosteroids therapy in bronchial asthma children.

  2. Data suggest that radioactive I(131) therapy leads to down-regulation of secretion of ECP from Th2 cells (helper-inducer T-lymphocytes) in post-thyroidectomy patients treated for differentiated thyroid cancer; in this study, ECP levels in serum were analyzed before, 3 days after, and 7 days after radiotherapy with I(131).

  3. our data add new insights into the pathophysiology of AD, suggesting that BDNF (show BDNF Proteins) which correlates with disease severity and ECP levels contributes to the regulation of inflammation in an eosinophil-, but not Th2-dependent manner.

  4. High circulating levels of eosinophil cationic protein are associated with increased incidence of ischemic stroke.

  5. Studies mapped the structural determinants required for the eosinophil cationic protein (ECP)-bacterial lipopolysaccharide (LPS (show IRF6 Proteins)) interaction by nuclear magnetic resonance.

  6. Increased MRP8/14 levels suggest the instability of the atherosclerotic plaque. ECP reflects the severity of coronary arteries stenosis, predicting atherosclerosis burden. They may become the new biomarkers of CAD.

  7. Children in the acute-phase group showed higher ECP mRNA expression level than those in the stable-phase and healthy control groups, while the level in the stable-phase was markedly higher than that in the healthy control group.

  8. drug eluting stent polymers increase eosinophil cationic protein levels following percutaneous coronary intervention independently of C-reactive protein (show CRP Proteins)

  9. Around half of all variance in serum ECP is explained by genetic factors. Serum ECP is influenced by sex, BMI, and airway responsiveness. Serum ECP and airway responsiveness seem not to share genetic variance.

  10. eosinophil cationic protein levels can be used to diagnosis atopic dermatitis but cannot distinguish between intrinsic and extrinsic disease.

Eosinophil Cationic Protein (ECP) Protein Profile

Protein Summary

Cytotoxin and helminthotoxin with ribonuclease activity. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.

Gene names and symbols associated with ECP

  • eosinophil-associated, ribonuclease A family, member 11 (Ear11)
  • eosinophil-associated, ribonuclease A family, member 2 (Ear2)
  • ribonuclease 3 (RNS3)
  • ribonuclease A family member 3 (RNASE3)
  • ribonuclease A family member 2 (RNASE2)
  • 2 protein
  • EAR protein
  • EAR-2 protein
  • EAR-13 protein
  • ECP protein
  • ECP 2 protein
  • R1 protein
  • R7 protein
  • ribonuclease 3 protein
  • RNASE2 protein
  • Rnase3 protein
  • RNS3 protein
  • T24P13.23 protein

Protein level used designations for ECP

EAR-11 , RNase 3 , eosinophil cationic protein , eosinophil secondary granule ribonuclease 11 , eosinophil-associated ribonuclease , ribonuclease 1 , ribonuclease 3 , ribonuclease 7 , RNase 3-2 , eosinophil cationic protein 2 , eosinophil secondary granule ribonuclease 2 , eosinophil-associated ribonuclease 13 , eosinophil-associated ribonuclease 2 , eosinophil-derived neurotoxin, liver , ribonuclease 3-2 , cytotoxic ribonuclease , ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)

GENE ID SPECIES
192264 Rattus norvegicus
13587 Mus musculus
839225 Arabidopsis thaliana
6037 Homo sapiens
100125948 Bos taurus
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