anti-Ets Variant 2 (ETV2) Antibodies

Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (By similarity).. Additionally we are shipping ETV2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ETV2 2116 O00321
ETV2 361544  
ETV2 14008 P41163
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Top anti-ETV2 Antibodies at

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-Etv2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Mouse Brain 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-ETV2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  721_B cell lysate 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-Etv2 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Mouse Lung 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ETV2 using K562 whole cell lysates 100 μL Log in to see 11 to 12 Days
Human Rabbit Un-conjugated WB Western blot analysis in K562 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA   100 μg Log in to see 11 to 14 Days

Top referenced anti-ETV2 Antibodies

  1. Human Polyclonal ETV2 Primary Antibody for ELISA - ABIN548183 : Knebel, De Haro, Janknecht: Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71. in Journal of cellular biochemistry 2006 (PubMed)

More Antibodies against ETV2 Interaction Partners

Xenopus laevis Ets Variant 2 (ETV2) interaction partners

  1. Data have identified the Xenopus ortholog of er71 and could show that er71 function in Xenopus is required for vasculogenesis, but not for the development of hematopoietic cells.

  2. An essential role for ETV2 in endothelial development.

Zebrafish Ets Variant 2 (ETV2) interaction partners

  1. These results demonstrate the requirement for Etv2 and Fli1b in tumor angiogenesis.

  2. low levels of Vegf signaling promote overall vascular endothelial differentiation and cell survival by upregulating etv2 expression, while high levels of Vegf signaling promote arterial and inhibit venous specification.

  3. results suggest that the LSD1-dependent shutdown of Etv2 gene expression may be a significant event required for hemangioblasts to initiate hematopoietic differentiation

  4. Etv2 alone is required for early vasculogenesis, whereas Etv2 and Fli1b function redundantly during late vasculogenesis and early embryonic angiogenesis.

  5. The results identify an etv2 cis-regulatory mechanism controlling cardiovascular fate choice implying that etv2 participates in a transcriptional network mediating developmental plasticity of endothelial progenitor cells during embryonic development.

  6. etv2 has a critical cell autonomous requirement during neutropoiesis in the anterior lateral plate mesoderm.

  7. etv2 acts during early development to specify endothelial lineages and is then down-regulated, in part through post-transcriptional repression by microRNAs, to allow normal vascular development.

  8. Expression of Etv2 alone is sufficient to transdifferentiate fast skeletal muscle into functional endothelial cells in vivo.

  9. substantially increased number of candidate genes regulated by etsrp in vascular cells

  10. Identify mesodermal foxc1a/b as a direct upstream regulator of etsrp in angioblasts. This establishes a new molecular link in the process of mesoderm specification into angioblast.

  11. These results argue that Etsrp initiates endothelial and endocardial, and inhibits myocardial, differentiation by two distinct mechanisms.

  12. Fli+ etsrp+ hemato-vascular progenitor cells proliferate at the lateral plate mesoderm during vasculogenesis in zebrafish.

  13. Etsrp function is needed for cranial artery & vein formation, despite low expression in cranial arteries. Cranial arterial & venous vasculature originates in the same midbrain- & rostral-organizing-center clusters affected by etsrp knockdown.

  14. Ets1-related protein plays a critical role in the initiation of definitive hematopoiesis by controlling the expression of 2 stem cell leukemia (scl) isoforms (scl-alpha and scl-beta) in angioblasts.

  15. etsrp embryonic expression is only restricted to vascular endothelial cells and their earliest precursors. Morpholino knockdown of Etsrp protein function resulted in the complete absence of circulation in zebrafish embryos.

  16. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp; choice of endothelial versus myeloid fate depends on a combinatorial effect of etsrp, scl, and alk8 genes

  17. fli1, and etsrp, demonstrated that erg and fli1 act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin

  18. identify a group of genes downstream of etsrp likely to be critical for vascular and/or myeloid development.

  19. Identification of vasculature-specific genes by microarray analysis of Etsrp/Etv2 overexpressing zebrafish embryos.

Human Ets Variant 2 (ETV2) interaction partners

  1. ETS transcription factor Etv2, a critical factor for haematopoietic and vascular development, is also required for haematopoietic regeneration. Etv2, which is silent in homeostatic HSCs, was transiently activated in regenerating HSPCs and was required for the HSC expansion and regeneration following bone marrow transplantation or haematopoietic injury.

  2. REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration.

  3. Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs.

  4. ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells.

  5. ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells.

  6. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp

Mouse (Murine) Ets Variant 2 (ETV2) interaction partners

  1. HIF1alpha activation of Etv2 in embryonic stem cells followed by NOTCH1 signaling is required for the generation arterial endothelial cells that are capable of arteriogenesis and revascularization of ischemic tissue.

  2. This study aimed to evaluate the effects of the E-twenty six (ETS) factor Ets variant 2 (ETV2) gene expression in angiogenesis and the effect of ETV2 gene therapy in a mouse model of hindlimb ischemia.

  3. Foxh1 regulated FLK1+ mesoderm formation in mouse embryonic stem cells, which in turn specifies hemangiogenic fate via Etv2.

  4. findings demonstrate a critical role for Etv2-miR-130a-Jarid2 in vascular patterning both in vitro and in vivo

  5. These findings demonstrate that Etv2 is an important regulator of hematopoietic regeneration.

  6. Study discuss the functional significance of ETV2 in embryonic vessel development, postnatal angiogenesis and direct cell reprogramming. [review]

  7. Etv2 transactivates miR-130a in the endothelial progenitors.

  8. Endothelial ETV2 is required for postnatal vascular repair and regeneration.

  9. studies define upstream and downstream networks that serve as a transcriptional rheostat to regulate Etv2 gene expression

  10. These findings highlight the critical role that transient ETV2 expression plays in the regulation of hematopoietic and endothelial cell lineage specification and stability.

  11. Data indicate that transcription factor Mesp1 interacts physically with cAMP-responsive element binding protein 1 (Creb1) and transcriptionally regulates Ets variant 2 (Etv2) gene expression.

  12. ETV2 directly regulates Sox7, and ETV2 governs endothelial development by regulating transcriptional networks which include Sox7.

  13. We show that ER71 directly interacts with OVOL2 and that such interaction is critical for FLK1(+) cell generation and their differentiation into downstream cell lineages.

  14. Fli1 acts downstream of Etv2 to govern cell survival and vascular homeostasis via positive autoregulation in vasculogenesis.

  15. Gata2 functions as a cofactor of Etv2 in the transcriptional regulation of mesodermal progenitors during embryogenesis.

  16. study demonstrated using the embryonic stem cell/embryoid body system that Etv2 could rescue the Flk1 mutant phenotype, but Flk1 could not rescue the Etv2 mutant phenotype, further supporting the notion that the Flk1-Etv2 cascade is operational during hemato-endothelial development

  17. study to show the critical timeframe of Etv2 requirement and help to know if Etv2 has any function around E9.5 when most endothelial cells(EC) have completed differentiation; also tried to examine if Etv2 expression can define a distinct intermediate step of EC differentiation from Flk-1+/VECAD- mesoderm to VECAD+ differentiated ECs

  18. VEGF activates Etv2 by signaling through Flk1, which activates Creb through the p38 MAPK signaling cascade.

  19. Studies demonstrate that Etv2 is expressed during and required for yolk sac hematoendothelial development, and that Lmo2 is one of the downstream targets of Etv2.

  20. ETV2 marks hemogenic endothelium in gastrulating embryos and is absolutely required for the formation of this precursor at the onset of hematopoiesis.

ETV2 Antigen Profile

Protein Summary

Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA-3' (By similarity).

Gene names and symbols associated with anti-Ets Variant 2 (ETV2) Antibodies

  • ETS variant 2 (ETV2) antibody
  • ets variant 2 L homeolog (etv2.L) antibody
  • ets variant 2 (etv2) antibody
  • ets variant 2 (Etv2) antibody
  • ER71 antibody
  • ets1b antibody
  • etsrp antibody
  • Etsrp71 antibody
  • ETV2 antibody
  • MGC115679 antibody
  • wu:fc49b07 antibody
  • zgc:153819 antibody

Protein level used designations for anti-Ets Variant 2 (ETV2) Antibodies

ETS translocation variant 2 , ets variant 2 , ets variant gene 2 , Ets1-related protein , er71 , v-ets erythroblastosis virus E26 oncogene homolog 1b , ets-related protein 71 , ets related protein 71

514231 Bos taurus
612646 Canis lupus familiaris
734657 Xenopus laevis
555766 Danio rerio
2116 Homo sapiens
361544 Rattus norvegicus
14008 Mus musculus
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