anti-Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) Antibodies

EEF1A1 encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. Additionally we are shipping eEF1A1 Proteins (21) and eEF1A1 Kits (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EEF1A1 1915 P68104
EEF1A1 13627 P10126
EEF1A1 171361 P62630
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Top anti-eEF1A1 Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EEF1A1 Antibody Titration:  2.5ug/ml  Positive Control:  HepG2 cell lysate EEF1A1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Host:  Mouse  Target Name:  EEF1A1  Sample Tissue:  Mouse Pancreas  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of EEF1A1 Antibody (N-term) (ABIN390520) in Y79, T47D cell line lysates (35 µg/lane). EEF1A1 (arrow) was detected using the purified polyclonal antibody. (LEFT)Formalin-fixed and paraffin-embedded human brain with EEF1A1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (RIGHT)Flow cytometric analysis of NCI-H292 cells using EEF1A1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of EEF1A (AcK146) expression in H9C2 PMA-treated (A) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$575.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of EEF1A1 Antibody (C-term) (ABIN390521) in MCF-7 cell line lysates (35 µg/lane). EEF1A1 (arrow) was detected using the purified polyclonal antibody. Flow cytometric analysis of NCI-H292 cells using EEF1A1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB WB Image Sample(30 μg of whole cell lysate) A:293T 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed frozen sections of mouse hippocampus labeled with Anti-EF1 Alpha Polyclonal Antibody, Unconjugated (ABIN741210) followed by conjugation to the secondary antibody Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-EF1a Polyclonal Antibody, Unconjugated (ABIN741210) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of EF-Tu using LOVO whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details

Top referenced anti-eEF1A1 Antibodies

  1. Human Polyclonal eEF1A1 Primary Antibody for FACS, IHC (p) - ABIN390520 : Byun, Han, Lee, Kim, Ko, Yoon, Lee, Hong, Lee: Cathepsin D and eukaryotic translation elongation factor 1 as promising markers of cellular senescence. in Cancer research 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal eEF1A1 Primary Antibody for IHC - ABIN966029 : Woriax, Burkhart, Spremulli: Cloning, sequence analysis and expression of mammalian mitochondrial protein synthesis elongation factor Tu. in Biochimica et biophysica acta 1996 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal eEF1A1 Primary Antibody for ELISA, WB - ABIN546223 : Scaggiante, Dapas, Bonin, Grassi, Zennaro, Farra, Cristiano, Siracusano, Zanconati, Giansante, Grassi: Dissecting the expression of EEF1A1/2 genes in human prostate cancer cells: the potential of EEF1A2 as a hallmark for prostate transformation and progression. in British journal of cancer 2012 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal eEF1A1 Primary Antibody for WB - ABIN2783254 : Zhang, Zhang, Hou, Liang, Li, Wang: The novel gene AngRem104 downregulates glucocorticoid receptor expression and activates NF-kappaB in human mesangial cells. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal eEF1A1 Primary Antibody for ELISA, WB - ABIN1327605 : Zhang, Guo, Mi, Gao, Bhattacharya, Li, Kuo: EF1A1-actin interactions alter mRNA stability to determine differential osteopontin expression in HepG2 and Hep3B cells. in Experimental cell research 2008 (PubMed)

More Antibodies against eEF1A1 Interaction Partners

Human Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. The functional studies of specific methylation sites found them to have distinct effects, notably on Eukaryotic elongation factor 1A (eEF1A)-related processes of translation and tRNA aminoacylation.

  2. A strong correlation was found between the dysregulation of eEF1A synthesis and Alzheimer's Disease-associated synaptic failure.

  3. the different kinases that recognize the Ser and Thr residues of the eEF1A1 and eEF1A2 isoforms and regulate their involvement in different cellular processes like cell survival and apoptosis.

  4. Taken together, these findings enabled us to identify a novel mechanism by which eEF1A1 regulates the cell cycle's G1 phase to promote tumor proliferation by regulating cyclin D1 expression through STAT1 signaling in HCC.

  5. Methylation of lysine (K36) in eukaryotic elongation factor alpha (eEF1A) proteins is dependent on EEF1A lysine methyltransferase 4 (eEF1A-KMT4) in vivo.

  6. The present study identifies METTL21B as the enzyme responsible for methylation of eEF1A on Lys-165 and shows that this modification is dynamic, inducible and likely of regulatory importance.

  7. EEF1A1 is somatically mutated in 9% of follicular lymphoma tumors.

  8. we show how FAT10 stabilizes the translation elongation factor eEF1A1, which contributes to cancer cell proliferation

  9. The expression of RPL13A and EEF1A1 was not affected by differentiation, thus being these genes the most stable candidates as reference genes for RT-PCR.

  10. Study demonstrated that PAK4 interacted with eEF1A1 to promote migration and invasion of gastric cancer cells, thereby providing new insights into the function of PAK4 and eEF1A1 in the progression of gastric cancer.

  11. this study demonstrates that eEF1A1 regulates the subcellular location of expanded poly(A) proteins and is therefore a potential therapeutic target for combating the pathogenesis of poly(A) diseases.

  12. analysis of eEF1A1 oligomerization reveals that specific cysteine residues are required for this oligomerization activity

  13. Data (including data from studies using purified proteins/hepatocyte lysates) suggest eEF1A1/Sgt1a interact as multimer; D2/D3 domains of eEF1A1 and TPR domain of Sgt1 are involved in multimer formation; Sgt1 competes with viral RNA to bind to eEF1A.

  14. Data indicate that the methylation of lysine (Lys) in elongation factor 1A (eEF1A) by methyltransferase is conserved from yeast to human.

  15. ROCK phosphorylated eEF1A1 is a novel substrate for TIMAP-PP1 underlining the complex regulatory role of TIMAP in the endothelium.

  16. Study found reduced levels of hippocampal eEF1A protein in Alzheimer's disease

  17. Our results provide novel information on the intracellular distribution and interaction of eEF1A isoforms.

  18. These results suggest that the antitumor effects of paclitaxel in breast cancer are mediated by activation of the AMPK/EF1alpha/FOXO3a signaling pathway.

  19. These results suggest that miR-33a-5p is downregulated during Japanese encephalitis virus infection, which contributes to viral replication by increasing the intracellular level of EEF1A1, an interaction partner of the viral NS3 and NS5 proteins.

  20. Low expression of eEF1A1 was associated with cervical squamous cell carcinoma.

Mouse (Murine) Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. Hepatic eEF1A-1 was increased in ob/ob mice maintained on AIN-76A diet. Liver eEF1A-1 is induced during severe hepatic steatosis and the onset of hepatic ER stress.

  2. Data show that translation elongation factor eEF1A1 coordinates the heat shock response by adjusting transcriptional yield to translational needs.

  3. Then expression level of EF1alpha remains constant during osteogenic differentiation of mouse bone marrow-derived mesenchymal stem cells.

  4. Identified are several GBX2 candidate target genes including ROBO1, PLXNA4, SLIT3, NRP1, PCDH15, USH2A, NOTCH2, and EEF1A1 that are likely to contribute many of the developmental defects observed in Gbx2 mutant organisms.

  5. Under some stressful stimulations IFIT1 may participate in cell death pathways by interaction with eEF1A.

  6. both eEF1A and MYPT1 have roles in EGCG signaling for cancer prevention through 67LR

  7. The cell death was associated with downregulation of eukaryotic translation elongation factor-1 alpha 1 (eEF1A1/EF-1alpha) expression in conjunction with accumulation of its mRNA in processing bodies (P bodies).

Pig (Porcine) Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. Genomic organization, polymorphism, chromosomal assignment and spatial and temporal expressions of EEF1A1 gene was presented.

  2. Collectively, these results suggest that eEF1A interacts with viral NS5A and negatively regulates the growth of classical swine fever virus.

  3. Promoter analysis revealed porcine TEF1 was regulated, in a TATA-independent manner, by a specific intact initiator element, and numerous binding motifs of multiple transcription factors, including SP1, CREB/ATF and AREB6.

Rabbit Eukaryotic Translation Elongation Factor 1 alpha 1 (EEF1A1) interaction partners

  1. Data (including data from studies using purified proteins/hepatocyte lysates) suggest eEF1A1/Sgt1a interact as multimer; D2/D3 domains of eEF1A1 and TPR domain of Sgt1 are involved in multimer formation; Sgt1 competes with viral RNA to bind to eEF1A.

  2. The A,A( *),A' helices region did not interact with actin; however, its removal eliminates the actin bundling activity of eEF1A, probably due to the destruction of a dimeric structure of eEF1A.

eEF1A1 (EEF1A1) Antigen Profile

Protein Summary

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.

Gene names and symbols associated with EEF1A1

  • eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) antibody
  • eukaryotic translation elongation factor 1 alpha 1 (Eef1a1) antibody
  • eukaryotic translation elongation factor 1 alpha 1b (eef1a1b) antibody
  • eukaryotic translation elongation factor 1 alpha 1 L homeolog (eef1a1.L) antibody
  • elongation factor 1-alpha (tufA) antibody
  • eukaryotic translation elongation factor 1 alpha 1a (eef1a1a) antibody
  • CCS-3 antibody
  • CCS3 antibody
  • EE1A1 antibody
  • EEF-1 antibody
  • EEF1A antibody
  • eEF1A-1 antibody
  • eef1a-s antibody
  • EEF1A1 antibody
  • EEF1A2 antibody
  • Eef1a2l1 antibody
  • eef1as antibody
  • EF-1-ALPHA-S antibody
  • EF-1A antibody
  • EF-Tu antibody
  • EF1A antibody
  • EF1A1 antibody
  • fj64c02 antibody
  • GRAF-1EF antibody
  • HNGC:16303 antibody
  • LENG7 antibody
  • PTI1 antibody
  • RABEFLA2 antibody
  • SI antibody
  • wu:fj34g08 antibody
  • wu:fj64c02 antibody
  • zgc:73138 antibody
  • zgc:110335 antibody

Protein level used designations for EEF1A1

CTCL tumor antigen , EF-1-alpha-1 , EF1a-like protein , cervical cancer suppressor 3 , elongation factor 1 alpha subunit , elongation factor 1-alpha 1 , elongation factor Tu , eukaryotic elongation factor 1 A-1 , eukaryotic translation elongation factor 1 alpha 1-like 14 , glucocorticoid receptor AF-1 specific elongation factor , leukocyte receptor cluster (LRC) member 7 , leukocyte receptor cluster member 7 , prostate tumor-inducing protein 1 , translation elongation factor 1 alpha 1-like 14 , EF-Tu , eEF1A-1 , elongation factor 1 A-1 , EF-1 alpha2 , eukaryotic translation elongation factor 1 alpha 2 like 1 , elongation factor 1 alpha , eukaryotic translation elongation factor 1 alpha 2 , eukaryotic translation elongation factor 1 alpha 1 , Elongation factor 1-alpha 1-like protein , elongation factor 1a , EF-1 alpha , elongation factor 1-alpha, somatic form , elongation factor-1 alpha , eukaryotic translation elongation factor 1 alpha, somatic form , Elongation factor Tu , Eukaryotic elongation factor 1 A-1 , elongation factor EF-1 alpha , eukaryotic translation elongation factor 1 alpha 1-like

GENE ID SPECIES
1915 Homo sapiens
13627 Mus musculus
171361 Rattus norvegicus
373963 Gallus gallus
403506 Canis lupus familiaris
574059 Sus scrofa
716010 Macaca mulatta
100004503 Danio rerio
100303511 Saccoglossus kowalevskii
282220 Bos taurus
100009189 Oryctolagus cuniculus
493922 Felis catus
100009682 Equus caballus
386604 Xenopus laevis
801571 Cyanophora paradoxa
100689276 Cricetulus griseus
100720380 Cavia porcellus
336334 Danio rerio
101925273 Macaca fascicularis
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