anti-Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) Antibodies

EIF4A3 encodes a member of the DEAD box protein family. Additionally we are shipping Eukaryotic Translation Initiation Factor 4A3 Proteins (18) and Eukaryotic Translation Initiation Factor 4A3 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF4A3 9775 P38919
EIF4A3 192170 Q91VC3
EIF4A3 688288 Q3B8Q2
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Top anti-Eukaryotic Translation Initiation Factor 4A3 Antibodies at antibodies-online.com

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EIF4A3 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  OVCAR-3 cell lysate EIF4A3 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DDX48 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate EIF4A3 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$493.17
Details
Chicken Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB ABIN6272915 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of A549 cells, using EIF4A3 antibody. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IF, IHC, IP, WB Western blot analysis of extracts of various cell lines, using EIF4A3 antibody (ABIN1872497) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western blot analysis in MCF-7 cell line lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Chicken Rabbit Un-conjugated IF, IHC, IHC (p), IP, WB Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
$639.83
Details
Cow Rabbit Un-conjugated IF, IHC, IHC (p), IP Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
$639.83
Details
Caenorhabditis elegans Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$446.88
Details

More Antibodies against Eukaryotic Translation Initiation Factor 4A3 Interaction Partners

Human Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) interaction partners

  1. EIF4A3-induced circMMP9 is an important underlying mechanism in GBM cell proliferation.

  2. FAL1 may work as a ceRNA to modulate AKT1 expression via competitively binding to miR-637 in HSCR.

  3. we firstly report that the lncRNA H19 recruits eIF4A3 and promotes the colorectal cancer cell proliferation

  4. High EIF4A expression is associated with malignant peripheral nerve sheath tumors and vestibular schwannomas.

  5. MYC, DUX4, and EIF4A3 might contribute to facioscapulohumeral dystrophy pathophysiology

  6. Host eIF4AIII RNA helicase is required for efficient human cytomegalovirus replication.

  7. EIF4A3 is a gene involved in RNA metabolism, plays a role in mandible, laryngeal, and limb morphogenesis. Richieri-Costa-Pereira syndrome is caused by mutations in EIF4A3.

  8. The binding mode of CWC22 to eIF4AIII reveals a facet of how MIF4G domains use their versatile structural frameworks to activate or inhibit DEAD-box proteins.

  9. CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

  10. demonstrate direct physical interactions between yeast Sgd1p and Fal1p, and between their human orthologs (NOM1 and eIF4AIII) in vitro and in vivo, identifying human NOM1 as a missing eIF4G-like interacting partner of eIF4AIII

  11. identification of eIF4AIII and Barentsz as components of a conserved protein complex that is essential for mRNA localization in flies and nonsense-mediated mRNA decay in mammals

  12. eIF4AIII represents a new functional class of DExH/D box proteins that act as RNA clamps or 'place holders' for the sequence-independent attachment of additional factors to RNAs.

  13. detection of autoantibodies to DDX48 may have clinical utility for the improved diagnosis of pancreatic cancer

  14. The stable association of multiprotein exon junction complex core with RNA is maintained by inhibition of eIF4AIII ATPase activity by MAGOH-Y14.

  15. crystal structure of a tetrameric exon junction core complex containing the DEAD-box adenosine triphosphatase eukaryotic initiation factor 4AIII bound to an ATP analog, MAGOH, Y14, a fragment of MLN51, and a polyuracil mRNA mimic

  16. Although it is dispensable for pre-mRNA splicing in vitro, eIF4A3 is required for splicing-dependent loading of the Y14-Magoh core heterodimer onto mRNA.

  17. Data show that eIF4AIII, a core exon junction complex (EJC) component loaded onto mRNAs by pre-mRNA splicing, is associated with neuronal mRNA granules and dendritic mRNAs.

  18. The nonsense-mediated-decay mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers.

  19. NMP 265, a common part of the nuclear matrix, is located in the nucleus via an N-terminal amino acid sequence.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) interaction partners

  1. we first show that Eif4a3 haploinsufficiency phenocopies aberrant neurogenesis and microcephaly of Magoh and Rbm8a mutant mice.we show that genetic ablation of one downstream pathway, p53, significantly rescues microcephaly of all 3 EJC mutant

  2. The knockdown of PRPF19 or EIF4A3 decreased splicing of Lhb, or of both beta subunit transcripts, respectively.

Xenopus laevis Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) interaction partners

  1. Eif4a3 is required for accurate splicing of the Xenopus laevis ryanodine receptor pre-mRNA

  2. Knockdown of the EJC component Eukaryotic initiation factor 4a3 (Eif4a3) in embryos of the frog Xenopus laevis results in full-body paralysis, with defects in sensory neuron, pigment cell, and cardiac development.

Eukaryotic Translation Initiation Factor 4A3 (EIF4A3) Antigen Profile

Protein Summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Gene names and symbols associated with EIF4A3

  • eukaryotic translation initiation factor 4A3 (EIF4A3) antibody
  • eukaryotic translation initiation factor 4A3 (Eif4a3) antibody
  • eukaryotic translation initiation factor 4A3 (eif4a3) antibody
  • eukaryotic initiation factor 4A-III (LOC100185906) antibody
  • eukaryotic translation initiation factor 4A3 S homeolog (eif4a3.S) antibody
  • Eukaryotic initiation factor 4A-III (if4a3) antibody
  • 2400003O03Rik antibody
  • ddx48 antibody
  • eIF4A-III antibody
  • eif4a3 antibody
  • eif4a3-B antibody
  • eif4aiii antibody
  • mKIAA0111 antibody
  • nmp265 antibody
  • nuk34 antibody
  • XeIF-4AIII antibody
  • zgc:56139 antibody

Protein level used designations for EIF4A3

ATP-dependent RNA helicase DDX48 , ATP-dependent RNA helicase eIF4A-3 , DEAD (Asp-Glu-Ala-Asp) box polypeptide 48 , DEAD box protein 48 , NMP 265 , eIF-4A-III , eIF4A-III , eukaryotic initiation factor 4A-III , eukaryotic initiation factor 4A-like NUK-34 , eukaryotic translation initiation factor 4A , hNMP 265 , nuclear matrix protein 265 , Eukaryotic translation initiation factor 4A , putative DEAD box polypeptide 48 , probable ATP-dependent RNA helicase DDX48 , eukaryotic translation initiation factor 4A3 , eukaryotic translation initiation factor 4A-like , eukaryotic initiation factor 4AIII , ATP-dependent RNA helicase DDX48-B , ATP-dependent RNA helicase eIF4A-3-B , DEAD box protein 48-B , eIF-4A-III-B , eIF4A-III-B , eukaryotic initiation factor 4A-III-B , eukaryotic translation initiation factor 4A isoform 3-B , eukaryotic translation initiation factor XeIF-4AIII

GENE ID SPECIES
9775 Homo sapiens
192170 Mus musculus
515145 Bos taurus
100101926 Sus scrofa
100135173 Xenopus (Silurana) tropicalis
100190303 Taeniopygia guttata
454941 Pan troglodytes
475922 Canis lupus familiaris
100026301 Monodelphis domestica
100056586 Equus caballus
100185906 Ciona intestinalis
100376751 Saccoglossus kowalevskii
100541698 Meleagris gallopavo
100584471 Nomascus leucogenys
394053 Danio rerio
399362 Xenopus laevis
416704 Gallus gallus
688288 Rattus norvegicus
100195929 Salmo salar
100728310 Cavia porcellus
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