anti-Eukaryotic Translation Initiation Factor 5B (EIF5B) Antibodies

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. Additionally we are shipping EIF5B Proteins (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF5B 9669 O60841
EIF5B 226982 Q05D44
EIF5B 308306 B2GUV7
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Top anti-EIF5B Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-EIF5B AntibodyTitration: 1.0 µg/mL Positive Control: Jurkat Whole Cell EIF5B is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, IHC, WB Immunohistochemical analysis of EIF5B staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of EIF5B expression in A549 (A), Jurkat (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat/HepG2/A549 cells, using EIF5B Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, WB Western blot analysis of EIF5B expression in various lysates ABIN6275123 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 to 12 Days
$390.77
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of EIF5B expression in transfected 293T cell line by EIF5B MaxPab polyclonal antibody.Lane 1: EIF5B transfected lysate(134.2 KDa).Lane 2: Non-transfected lysate. EIF5B MaxPab polyclonal antibody. Western Blot analysis of EIF5B expression in human placenta. 50 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry (IHC) analyzes of eIF5B antibody in paraffin-embedded human breast carcinoma tissue. Western blot (WB) analysis of eIF5B antibody in extracts from Jurkat cells. 0.1 mg 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Available
$363.46
Details
Human Rabbit Un-conjugated IF/ICC Immunofluorescence analysis of A549 cells using EIF5B antibody (ABIN5973490). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IF Immunofluorescence analysis of A549 cells using EIF5B antibody. 200 μL 12 to 14 Days
$438.90
Details

Top referenced anti-EIF5B Antibodies

  1. Human Polyclonal EIF5B Primary Antibody for ELISA, WB - ABIN564178 : de Breyne, Bonderoff, Chumakov, Lloyd, Hellen: Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases. in Virology 2008 (PubMed)

More Antibodies against EIF5B Interaction Partners

Human Eukaryotic Translation Initiation Factor 5B (EIF5B) interaction partners

  1. results indicate that in humans, eIF5B displacing eIF2 from Met-tRNAi upon subunit joining may be coupled to eIF1A displacing eIF5 from eIF5B, allowing the eIF5:eIF2-GDP complex to leave the ribosome.

  2. aerobic eukarya retained eIF5B/IF2 to remodel anaerobic pathways during episodes of oxygen deficiency.

  3. eIF5B promoted hepatocellular carcinoma cell proliferation and migration in vitro and in vivo partly through increasing ASAP1 expression.

  4. eIF5B silencing provides a negative feedback to deactivate MAPK signaling

  5. results indicate that the interactions between eIF1A and eIF5B are being continuously rearranged during translation initiation; presentation of a model how the dynamic eIF1A/eIF5B interaction network can promote remodeling of the translation initiation complexes, and the roles in the process played by intrinsically disordered protein segments

  6. eIF5B overexpression promotes maturation of G0-like immature oocytes and causes cell death, an alternative to G0, in serum-starved THP1 cells.

  7. The authors show that the cleavage of initiation factor eIF5B during enteroviral infection, along with the viral internal ribosome entry site, plays a role in mediating viral translation under conditions that are nonpermissive for host cell translation.

  8. determination of binding site on eukaryotic initiation factor 1A

  9. Transfected nuclear factor 2 trans activates the IF2 promoter in a cell line.

  10. binding of eIF5B might induce conformational changes in both subunits, with ribosomal segments wrapping around the factor

  11. 3Cpro-mediated cleavage of eIF5B may thus play an accessory role in the shutoff of translation that occurs in enterovirus-infected cells.

Mouse (Murine) Eukaryotic Translation Initiation Factor 5B (EIF5B) interaction partners

  1. eIF5B overexpression promotes maturation of G0-like immature oocytes and causes cell death, an alternative to G0, in serum-starved THP1 cells.

  2. eIF5B, the homologue of bacterial IF2, is a GTPase implicated in joining the ribosomal subunits.

EIF5B Antigen Profile

Protein Summary

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Gene names and symbols associated with EIF5B

  • eukaryotic translation initiation factor 5B (EIF5B) antibody
  • eukaryotic translation initiation factor 5B (eif5b) antibody
  • eukaryotic translation initiation factor 5B (EDI_190850) antibody
  • eukaryotic translation initiation factor 5B (AOR_1_1690154) antibody
  • eukaryotic translation initiation factor 5B (CMU_007690) antibody
  • eukaryotic translation initiation factor 5B (POSPLDRAFT_134975) antibody
  • eukaryotic translation initiation factor 5B (POSPLDRAFT_134953) antibody
  • eukaryotic translation initiation factor 5B (eIF5b) antibody
  • eukaryotic translation initiation factor 5B (MCYG_03474) antibody
  • eukaryotic translation initiation factor 5B (PITG_20386) antibody
  • eukaryotic translation initiation factor 5B (eif5B) antibody
  • eukaryotic translation initiation factor 5B (MGYG_03082) antibody
  • translation initiation factor IF-2 (PGTG_13938) antibody
  • eukaryotic translation initiation factor 5B (Eif5b) antibody
  • A030003E17Rik antibody
  • AO090003000953 antibody
  • BC018347 antibody
  • CIF2 antibody
  • DDBDRAFT_0206214 antibody
  • DDBDRAFT_0234259 antibody
  • DDB_0206214 antibody
  • DDB_0234259 antibody
  • EIF5B antibody
  • IF2 antibody
  • im:6912504 antibody
  • MGC134193 antibody
  • si:ch211-254d18.3 antibody

Protein level used designations for EIF5B

initiation of translation factor 2 , eukaryotic translation initiation factor 5B , eIF-5B , translation initiation factor IF-2 , translation initiation factor IF2 , annexin V-binding protein ABP-7

GENE ID SPECIES
395514 Gallus gallus
474556 Canis lupus familiaris
532850 Bos taurus
561194 Danio rerio
5878760 Entamoeba dispar SAW760
5992052 Aspergillus oryzae RIB40
6995718 Cryptosporidium muris RN66
8141778 Postia placenta Mad-698-R
8146744 Postia placenta Mad-698-R
8621716 Dictyostelium discoideum AX4
9229290 Arthroderma otae CBS 113480
9480518 Phytophthora infestans T30-4
9621563 Volvox carteri f. nagariensis
10030865 Arthroderma gypseum CBS 118893
10538627 Puccinia graminis f. sp. tritici CRL 75-36-700-3
9669 Homo sapiens
226982 Mus musculus
308306 Rattus norvegicus
100460833 Pongo abelii
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